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2ku2

Dynamic Regulation of Archaeal Proteasome Gate Opening as Studied by TROSY-NMR

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Proteasome subunit alpha

Thermoplasma acidophilum

UniProt P25156

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 7 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers
2ku1 2ku2

2 assemblies

Heteromeric or nucleic-acid complex
1pma 1ya7 1yar 1yau 3c91 3c92 3ipm 3j9i 3jrm 3jse 3jtl 5vy3

23 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PSMA_THEAC
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 5–237； UniProt 1–233 Author chain B； PDBConstruct 5–237； UniProt 1–233 Author chain C； PDBConstruct 5–237； UniProt 1–233 Author chain D； PDBConstruct 5–237； UniProt 1–233 Author chain E； PDBConstruct 5–237； UniProt 1–233 Author chain F； PDBConstruct 5–237； UniProt 1–233 Author chain G； PDBConstruct 5–237； UniProt 1–233

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2ku2
Deposition date deposition_date2010-02-11
Structure title titleDynamic Regulation of Archaeal Proteasome Gate Opening as Studied by TROSY-NMR
Keywords keywordsproteasome, proteolysis, gating residues, Cytoplasm, Hydrolase, Protease, Threonine protease; HYDROLASE
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2ku2__assembly_1__model_16

Assembly 1 · Model 16 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2ku2__assembly_1__model_16 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2ku2__assembly_1__model_16 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）39.99 Å
Rg (electron density)39.93 Å
Total Rg40.31 Å
Atom count25802
Residues1659
Excluded volume228820 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2ku2__assembly_1__model_1 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 2ku2__assembly_1__model_2 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 2ku2__assembly_1__model_3 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 2ku2__assembly_1__model_4 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 2ku2__assembly_1__model_5 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 2ku2__assembly_1__model_6 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 2ku2__assembly_1__model_7 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 2ku2__assembly_1__model_8 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 2ku2__assembly_1__model_9 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 2ku2__assembly_1__model_10 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 2ku2__assembly_1__model_11 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 2ku2__assembly_1__model_12 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 2ku2__assembly_1__model_13 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 2ku2__assembly_1__model_14 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 2ku2__assembly_1__model_15 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 2ku2__assembly_1__model_16 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 2ku2__assembly_1__model_17 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 2ku2__assembly_1__model_18 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 2ku2__assembly_1__model_19 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 2ku2__assembly_1__model_20 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 21 2ku2__assembly_1__model_21 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 22 2ku2__assembly_1__model_22 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 23 2ku2__assembly_1__model_23 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 24 2ku2__assembly_1__model_24 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 25 2ku2__assembly_1__model_25 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 26 2ku2__assembly_1__model_26 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 27 2ku2__assembly_1__model_27 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 28 2ku2__assembly_1__model_28 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 29 2ku2__assembly_1__model_29 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 30 2ku2__assembly_1__model_30 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 31 2ku2__assembly_1__model_31 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 32 2ku2__assembly_1__model_32 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 33 2ku2__assembly_1__model_33 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 34 2ku2__assembly_1__model_34 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 35 2ku2__assembly_1__model_35 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 36 2ku2__assembly_1__model_36 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 37 2ku2__assembly_1__model_37 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 38 2ku2__assembly_1__model_38 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 39 2ku2__assembly_1__model_39 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 40 2ku2__assembly_1__model_40 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 41 2ku2__assembly_1__model_41 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 42 2ku2__assembly_1__model_42 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 43 2ku2__assembly_1__model_43 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 44 2ku2__assembly_1__model_44 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 45 2ku2__assembly_1__model_45 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 46 2ku2__assembly_1__model_46 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 47 2ku2__assembly_1__model_47 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 48 2ku2__assembly_1__model_48 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 49 2ku2__assembly_1__model_49 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
1 50 2ku2__assembly_1__model_50 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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6. Fold Classification (SCOP + CATH) 21 domains

SCOP 2.08 (14 domains)

Domain ID domain_idd2ku2a1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.153 — Ntn hydrolase-like
Superfamily Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family Family familyd.153.1.4 — Proteasome subunits
Domain ID domain_idd2ku2a2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd2ku2b1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.153 — Ntn hydrolase-like
Superfamily Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family Family familyd.153.1.4 — Proteasome subunits
Domain ID domain_idd2ku2b2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd2ku2c1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.153 — Ntn hydrolase-like
Superfamily Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family Family familyd.153.1.4 — Proteasome subunits
Domain ID domain_idd2ku2c2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd2ku2d1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.153 — Ntn hydrolase-like
Superfamily Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family Family familyd.153.1.4 — Proteasome subunits
Domain ID domain_idd2ku2d2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd2ku2e1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.153 — Ntn hydrolase-like
Superfamily Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family Family familyd.153.1.4 — Proteasome subunits
Domain ID domain_idd2ku2e2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd2ku2f1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.153 — Ntn hydrolase-like
Superfamily Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family Family familyd.153.1.4 — Proteasome subunits
Domain ID domain_idd2ku2f2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd2ku2g1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.153 — Ntn hydrolase-like
Superfamily Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family Family familyd.153.1.4 — Proteasome subunits
Domain ID domain_idd2ku2g2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags

CATH v4.4 (7 domains)

Domain ID domain_id2ku2A00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id2ku2B00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id2ku2C00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id2ku2D01
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id2ku2E01
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id2ku2F01
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id2ku2G01
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
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7. Citations (1)