← Back to search
3ipm

Crystal Structure of Archaeal 20S Proteasome in Complex with the C-terminus of PAN

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Proteasome subunit alpha

Thermoplasma acidophilum

UniProt P25156

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 42 Proteasome subunit beta × 14 （P28061） Proteasome activator PA26, Proteasome-activating nucleotidase fusion protein × 14 （Q38BM8,Q58576） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers
2ku1 2ku2

2 assemblies

Heteromeric or nucleic-acid complex
1pma 1ya7 1yar 1yau 3c91 3c92 3ipm 3j9i 3jrm 3jse 3jtl 5vy3

23 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PSA_THEAC
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–233； UniProt 1–233 Author chain B； PDBConstruct 1–233； UniProt 1–233 Author chain C； PDBConstruct 1–233； UniProt 1–233 Author chain D； PDBConstruct 1–233； UniProt 1–233 Author chain E； PDBConstruct 1–233； UniProt 1–233 Author chain F； PDBConstruct 1–233； UniProt 1–233 Author chain G； PDBConstruct 1–233； UniProt 1–233

Proteasome subunit beta

Thermoplasma acidophilum

UniProt P28061

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 42 Proteasome subunit alpha × 14 （P25156） Proteasome activator PA26, Proteasome-activating nucleotidase fusion protein × 14 （Q38BM8,Q58576） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1pma 1ya7 1yar 1yau 3c91 3c92 3ipm 3j9i 3jrm 3jse 3jtl 5vy3

23 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PSB_THEAC
Isoform —
PDB entities 2
Chains and sequence ranges Author chain H； PDBConstruct 1–211； UniProt 1–211 Author chain I； PDBConstruct 1–211； UniProt 1–211 Author chain J； PDBConstruct 1–211； UniProt 1–211 Author chain K； PDBConstruct 1–211； UniProt 1–211 Author chain L； PDBConstruct 1–211； UniProt 1–211 Author chain M； PDBConstruct 1–211； UniProt 1–211 Author chain N； PDBConstruct 1–211； UniProt 1–211

Proteasome activator PA26, Proteasome-activating nucleotidase fusion protein

Methanocaldococcus jannaschii

UniProt Q38BM8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 42 Proteasome subunit alpha × 14 （P25156） Proteasome subunit beta × 14 （P28061） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3ipm 6uth 6utj

3 assemblies

View Construct and Data Evidence
UniProt name Q38BM8_TRYB2
Isoform —
PDB entities 3
Chains and sequence ranges Author chain O； PDBConstruct 9–230； UniProt 2–223 Author chain P； PDBConstruct 9–230； UniProt 2–223 Author chain Q； PDBConstruct 9–230； UniProt 2–223 Author chain R； PDBConstruct 9–230； UniProt 2–223 Author chain S； PDBConstruct 9–230； UniProt 2–223 Author chain T； PDBConstruct 9–230； UniProt 2–223 Author chain U； PDBConstruct 9–230； UniProt 2–223

Proteasome activator PA26, Proteasome-activating nucleotidase fusion protein

Methanocaldococcus jannaschii

UniProt Q58576

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 42 Proteasome subunit alpha × 14 （P25156） Proteasome subunit beta × 14 （P28061） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
3h4m 3h4m 3h4m

3 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
3h43 3h43 3h43

3 assemblies

Heteromeric or nucleic-acid complex
3ipm

1 assemblies

View Construct and Data Evidence
UniProt name PAN_METJA
Isoform —
PDB entities 3
Chains and sequence ranges Author chain O； PDBConstruct 233–239； UniProt 424–430 Author chain P； PDBConstruct 233–239； UniProt 424–430 Author chain Q； PDBConstruct 233–239； UniProt 424–430 Author chain R； PDBConstruct 233–239； UniProt 424–430 Author chain S； PDBConstruct 233–239； UniProt 424–430 Author chain T； PDBConstruct 233–239； UniProt 424–430 Author chain U； PDBConstruct 233–239； UniProt 424–430

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id3ipm
Deposition date deposition_date2009-08-17
Structure title titleCrystal Structure of Archaeal 20S Proteasome in Complex with the C-terminus of PAN
Keywords keywords;Proteasome, proteasomal ATPase, protein degradation, AAA ATPase, electron cryomicroscopy, Hydrolase, Protease, Threonine protease, HYDROLASE-HYDROLASE ACTIVATOR COMPLEX ;; HYDROLASE/HYDROLASE ACTIVATOR
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3ipm__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3ipm__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3ipm__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）80.31 Å
Rg (electron density)80.80 Å
Total Rg80.63 Å
Atom count70266
Residues9086
Excluded volume1260200 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3ipm__assembly_1__model_1 42-meric （42） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (3)

▼

6. Fold Classification (SCOP + CATH) 21 domains

CATH v4.4 (21 domains)

Domain ID domain_id3ipmA00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmB00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmC00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmD00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmE00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmF00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmG00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmH00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmI00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmJ00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmK00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmL00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmM00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmN00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Homologous superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
Domain ID domain_id3ipmO01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily180 — Proteasome activator pa28, C-terminal domain
Domain ID domain_id3ipmP01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily180 — Proteasome activator pa28, C-terminal domain
Domain ID domain_id3ipmQ01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily180 — Proteasome activator pa28, C-terminal domain
Domain ID domain_id3ipmR01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily180 — Proteasome activator pa28, C-terminal domain
Domain ID domain_id3ipmS01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily180 — Proteasome activator pa28, C-terminal domain
Domain ID domain_id3ipmT01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily180 — Proteasome activator pa28, C-terminal domain
Domain ID domain_id3ipmU01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily180 — Proteasome activator pa28, C-terminal domain
▶

7. Citations (1)