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2mjw

Structural Insights into Calcium Bound S100P - V Domain of the receptor for advanced glycation end products (RAGE) Complex

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Advanced glycosylation end product-specific receptor

Homo sapiens

UniProt Q15109

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Protein S100-P × 2 （P25815） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2e5e 2ens 2lmb 2mov 3cjj 4lp4 4lp4 4lp5 4lp5 4of5 4of5 4ofv

17 assemblies; showing the first 12

Homodimer
7lml 7lmw

2 assemblies

Homotetramer
6xq1 6xq3 6xq5 6xq6 6xq7 6xq8

6 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
2l7u 2le9 2m1k 2mjw 3o3u 4oi7 4oi8 4p2y 4p2y 4p2y 4ybh 5d7f

14 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name RAGE_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 3–101； UniProt 23–121 Author chain C； PDBConstruct 3–101； UniProt 23–121

Protein S100-P

Homo sapiens

UniProt P25815

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Advanced glycosylation end product-specific receptor × 2 （Q15109） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1j55 1ozo

2 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2mjw 7nmi

2 assemblies

View Construct and Data Evidence
UniProt name S100P_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–94； UniProt 1–94 Author chain D； PDBConstruct 1–94； UniProt 1–94

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2mjw
Deposition date deposition_date2014-01-19
Structure title titleStructural Insights into Calcium Bound S100P - V Domain of the receptor for advanced glycation end products (RAGE) Complex
Keywords keywordsS100P V Domain of RAGE, SIGNALING PROTEIN-METAL BINDING PROTEIN complex; SIGNALING PROTEIN/METAL BINDING PROTEIN
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2mjw__assembly_1__model_8

Assembly 1 · Model 8 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2mjw__assembly_1__model_8 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2mjw__assembly_1__model_8 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）24.20 Å
Rg (electron density)23.26 Å
Total Rg24.24 Å
Atom count6072
Residues390
Excluded volume53998 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2mjw__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 2mjw__assembly_1__model_2 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 2mjw__assembly_1__model_3 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 2mjw__assembly_1__model_4 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 2mjw__assembly_1__model_5 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 2mjw__assembly_1__model_6 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 2mjw__assembly_1__model_7 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 2mjw__assembly_1__model_8 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 2mjw__assembly_1__model_9 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 2mjw__assembly_1__model_10 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd2mjwb_
Class classa — All alpha proteins
Fold Fold folda.39 — EF Hand-like
Superfamily Superfamily superfamilya.39.1 — EF-hand
Family Family familya.39.1.2 — S100 proteins
Domain ID domain_idd2mjwd_
Class classa — All alpha proteins
Fold Fold folda.39 — EF Hand-like
Superfamily Superfamily superfamilya.39.1 — EF-hand
Family Family familya.39.1.2 — S100 proteins

CATH v4.4 (4 domains)

Domain ID domain_id2mjwA00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
Domain ID domain_id2mjwB00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology238 — Recoverin; domain 1
Homologous superfamily homologous superfamily10 — EF-hand
Domain ID domain_id2mjwC00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
Domain ID domain_id2mjwD00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology238 — Recoverin; domain 1
Homologous superfamily homologous superfamily10 — EF-hand
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7. Citations (1)