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2le9

RAGEC2-S100A13 tetrameric complex

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Advanced glycosylation end product-specific receptor

Homo sapiens

UniProt Q15109

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Protein S100-A13 × 2 （Q99584） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2e5e 2ens 2lmb 2mov 3cjj 4lp4 4lp4 4lp5 4lp5 4of5 4of5 4ofv

17 assemblies; showing the first 12

Homodimer
7lml 7lmw

2 assemblies

Homotetramer
6xq1 6xq3 6xq5 6xq6 6xq7 6xq8

6 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
2l7u 2le9 2m1k 2mjw 3o3u 4oi7 4oi8 4p2y 4p2y 4p2y 4ybh 5d7f

14 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name RAGE_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–93； UniProt 235–327 Author chain D； PDBConstruct 1–93； UniProt 235–327

Protein S100-A13

Homo sapiens

UniProt Q99584

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Advanced glycosylation end product-specific receptor × 2 （Q15109） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1yur 1yus 1yut 1yuu 2egd 2h2k 2kot

7 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2k8m 2ki4 2ki6 2l5x 2le9

5 assemblies

View Construct and Data Evidence
UniProt name S10AD_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–97； UniProt 2–98 Author chain C； PDBConstruct 1–97； UniProt 2–98

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2le9
Deposition date deposition_date2011-06-14
Structure title titleRAGEC2-S100A13 tetrameric complex
Keywords keywordsReceptor for Advanced Glycation End products, S100A13, tetrameric complex, MEMBRANE PROTEIN-METAL BINDING PROTEIN complex; MEMBRANE PROTEIN/METAL BINDING PROTEIN
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2le9__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2le9__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2le9__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）26.98 Å
Rg (electron density)26.28 Å
Total Rg26.97 Å
Atom count5932
Residues380
Excluded volume52772 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2le9__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd2le9b_
Class classa — All alpha proteins
Fold Fold folda.39 — EF Hand-like
Superfamily Superfamily superfamilya.39.1 — EF-hand
Family Family familya.39.1.0 — automated matches
Domain ID domain_idd2le9c_
Class classa — All alpha proteins
Fold Fold folda.39 — EF Hand-like
Superfamily Superfamily superfamilya.39.1 — EF-hand
Family Family familya.39.1.0 — automated matches

CATH v4.4 (4 domains)

Domain ID domain_id2le9A00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
Domain ID domain_id2le9B00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology238 — Recoverin; domain 1
Homologous superfamily homologous superfamily10 — EF-hand
Domain ID domain_id2le9C00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology238 — Recoverin; domain 1
Homologous superfamily homologous superfamily10 — EF-hand
Domain ID domain_id2le9D00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
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7. Citations (1)