Mus musculus
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | PROTOPORPHYRIN IX CONTAINING FE × 1 2-{(2R)-4-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-1-ISOBUTYRYLPIPERAZIN-2-YL}-N-[2-(4-METHOXYPHENYL)ETHYL]ACETAMIDE × 1 water × 1 | 与蛋白数一致 |
| UniProt名称 | NOS2_MOUSE |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–385； UniProt 114–498 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 2orp |
| 沉积日期 deposition_date | 2007-02-04 |
| 结构标题 title | Murine inducible nitric oxide synthase oxygenase domain (delta 114) 2-[4-(2-Imidazol-1-yl-6-methyl-pyrimidin-4-yl)-1-isobutyryl-piperazin-2-yl]-N-[2-(4-methoxy-phenyl)-ethyl]-acetamide complex |
| 关键词 keywords | NITRIC OXIDE; L-ARGININE MONOOXYGENASE; HEME; DIMERIZATION; INHIBITOR; NOS, OXIDOREDUCTASE; OXIDOREDUCTASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 21.44 Å |
| Rg（电子密度） | 20.40 Å |
| 总 Rg | 21.43 Å |
| 原子数 | 2556 |
| 残基数 | 304 |
| 排除体积 | 45507 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d2orpa1 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.174 — Nitric oxide (NO) synthase oxygenase domain |
| 超家族 Superfamily superfamily | d.174.1 — Nitric oxide (NO) synthase oxygenase domain |
| 家族 Family family | d.174.1.1 — Nitric oxide (NO) synthase oxygenase domain |
| 结构域编号 domain_id | d2orpa2 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | 2orpA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 340 — Nitric Oxide Synthase; Chain A, domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Nitric Oxide Synthase; Chain A, domain 1 |
| 结构域编号 domain_id | 2orpA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 440 — Nitric Oxide Synthase;Heme Domain; Chain A, domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Nitric Oxide Synthase;Heme Domain;Chain A domain 2 |
| 结构域编号 domain_id | 2orpA03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 1230 — Bovine Endothelial Nitric Oxide Synthase Heme Domain; Chain: A,domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Nitric Oxide Synthase; Chain A, domain 3 |