SAXSdb — 2pys

▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Cyanovirin-N

Nostoc ellipsosporum

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Homooligomer	Protein 2 其他Polymer 2	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose × 2 water × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	CVN_NOSEL
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–101； UniProt 1–101 Author chain B； PDBConstruct 1–101； UniProt 1–101

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id	2pys
Deposition date deposition_date	2007-05-16
Structure title title	Crystal Structure of a Five Site Mutated Cyanovirin-N with a Mannose Dimer Bound at 1.8 A Resolution
Keywords keywords	CYANOVIRIN-N, SUGAR BINDING PROTEIN, ANTI HIV; SUGAR BINDING PROTEIN
Experimental Method method	X-RAY DIFFRACTION

▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2pys__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2pys__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

2pys__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	18.54 Å
Rg (electron density)	17.40 Å
Total Rg	18.29 Å
Atom count	1585
Residues	204
Excluded volume	27704 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2pys__assembly_1__model_1`	tetrameric （4）	Success	4.1.3-1-20251215 (887e7ef)	View Download

▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Description description	Cyanovirin-N
Molecular weight formula_weight	11949.1 kDa
Mutation mutation	K3N, T7A, E23I, P51G, N93A
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B
Atom count atom_count	1769

LGNFSQACYNSAIQGSVLTSTCIRTNGGYNTSSIDLNSVIENVDGSLKWQGSNFIETCRNTQLAGSSELAAECKTRAQQFVSTKINLDDHIAAIDGTLKYELEHHHHHH

Source Source

Source organism organism	Nostoc ellipsosporum
NCBI taxonomy ID ncbi_taxonomy_id	45916
Host organism host_organism	Escherichia coli

Entity 2 Entity 2 branched

Description description	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
Molecular weight formula_weight	342.3 kDa
Source method src_method	man
Copy count entity_count	2

Entity 3 Entity 3 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	184

▼

6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (4 domains)

Domain ID domain_id	d2pysa1
Class class	b — All beta proteins
Fold Fold fold	b.89 — Cyanovirin-N
Superfamily Superfamily superfamily	b.89.1 — Cyanovirin-N
Family Family family	b.89.1.1 — Cyanovirin-N

Domain ID domain_id	d2pysa2
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d2pysb1
Class class	b — All beta proteins
Fold Fold fold	b.89 — Cyanovirin-N
Superfamily Superfamily superfamily	b.89.1 — Cyanovirin-N
Family Family family	b.89.1.1 — Cyanovirin-N

Domain ID domain_id	d2pysb2
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

CATH v4.4 (2 domains)

Domain ID domain_id	2pysA00
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	60 — HIV-inactivating Protein, Cyanovirin-n
Homologous superfamily homologous superfamily	10 — Cyanovirin-N

Domain ID domain_id	2pysB00
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	60 — HIV-inactivating Protein, Cyanovirin-n
Homologous superfamily homologous superfamily	10 — Cyanovirin-N

▶

Unit-cell length a length_a	49.226 Å
Unit-cell length b length_b	38.281 Å
Unit-cell length c length_c	55.794 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	99.69 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	4

Space group space_group	P 1 21 1
Space-group number int_tables_number	4
Crystal system crystal_system	—

Resolution resolution	1.800 Å
Low-resolution limit resolution_low	9.990 Å
R factor r_factor	0.1710
R_work r_work	0.1690
R_free r_free	0.2150

Crystal Structure of a Five Site Mutated Cyanovirin-N with a Mannose Dimer Bound at 1.8 A Resolution

1. Protein Identity and Related Structures Protein Identity & Related Structures

Cyanovirin-N

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2pys__assembly_1__model_1

2pys__assembly_1__model_1 | I(q)

2pys__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 branched

Entity 3 Entity 3 water

6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (4 domains)

CATH v4.4 (2 domains)

7. Citations (1)

Crystal Structure of a Five Site Mutated Cyanovirin-N with a Mannose Dimer Bound at 1.8 A Resolution

1. Protein Identity and Related Structures Protein Identity & Related Structures

Cyanovirin-N

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2pys__assembly_1__model_1

2pys__assembly_1__model_1 | I(q)

2pys__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 branched

Entity 3 Entity 3 water

6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (4 domains)

CATH v4.4 (2 domains)

7. Citations (1)