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2v2t

X-ray structure of a NF-kB p50-RelB-DNA complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

TRANSCRIPTION FACTOR RELB

MUS MUSCULUS

UniProt Q04863

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 2 DNA 2 NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT × 1 （P25799） 5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*CP*CP*CP)-3' × 2 water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1zk9 1zka 3jss 3juz 3jv0 4jgm 4jhb

7 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2v2t 3jv4 3jv4 3jv4 3jv6 3jv6 3jv6

7 assemblies

View Construct and Data Evidence
UniProt name RELB_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–288； UniProt 91–378

NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT

MUS MUSCULUS

UniProt P25799

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 2 DNA 2 TRANSCRIPTION FACTOR RELB × 1 （Q04863） 5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*CP*CP*CP)-3' × 2 water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1bfs 1u36 1u3j 1u3y 1u3z 1u41 1u41 1u42

8 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1ikn 1le5 1le5 1le9 1le9 1lei 1nfk 1ooa 1ooa 1vkx 2i9t 2v2t

19 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name NFKB1_MOUSE
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–326； UniProt 38–363

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2v2t
Deposition date deposition_date2007-06-07
Structure title titleX-ray structure of a NF-kB p50-RelB-DNA complex
Keywords keywords;4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL, AQUIFEX AEOLICUS, NUCLEOTIDE-BINDING, ISOPRENE BIOSYNTHESIS, TRANSCRIPTION, KINASE, TRANSFERASE, ATP-BINDING, NON-MEVALONATE ;; TRANSCRIPTION
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2v2t__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2v2t__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2v2t__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）31.06 Å
Rg (electron density)31.43 Å
Total Rg31.70 Å
Atom count5100
Residues614
Excluded volume89064 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2v2t__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 8 domains

SCOP 2.08 (4 domains)

Domain ID domain_idd2v2ta1
Class classb — All beta proteins
Fold Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily Superfamily superfamilyb.2.5 — p53-like transcription factors
Family Family familyb.2.5.0 — automated matches
Domain ID domain_idd2v2ta2
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.18 — E set domains
Family Family familyb.1.18.0 — automated matches
Domain ID domain_idd2v2tb1
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.18 — E set domains
Family Family familyb.1.18.0 — automated matches
Domain ID domain_idd2v2tb2
Class classb — All beta proteins
Fold Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily Superfamily superfamilyb.2.5 — p53-like transcription factors
Family Family familyb.2.5.3 — Rel/Dorsal transcription factors, DNA-binding domain

CATH v4.4 (4 domains)

Domain ID domain_id2v2tA01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily340 — Rel homology domain (RHD), DNA-binding domain
Domain ID domain_id2v2tA02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
Domain ID domain_id2v2tB01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily340 — Rel homology domain (RHD), DNA-binding domain
Domain ID domain_id2v2tB02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
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7. Citations (1)