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2xxt

Crystal structure of the GluK2 (GluR6) wild-type LBD dimer in complex with kainate

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2

RATTUS NORVEGICUS

UniProt P42260

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE × 2 SODIUM ION × 2 CHLORIDE ION × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1s50 2i0b

2 assemblies

Homodimer
1s7y 1tt1 2i0b 2i0c 2xxr 2xxt 2xxu 2xxv 2xxw 2xxx 2xxx 2xxy

35 assemblies; showing the first 12

Homotetramer
1s9t 1sd3 4uqq 5kuf 5kuh 9b35 9c5y 9c5z 9c60 9caz 9dxt 9mzr

12 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
3qlu 3qlu 3qlv 3qlv 3qlv 3qlv 3qlv 3qlv 3qlv 3qlv 5cmm 7f56

58 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name GRIK2_RAT
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–117； UniProt 429–544 Author chain A； PDBConstruct 120–259； UniProt 667–806 Author chain B； PDBConstruct 2–117； UniProt 429–544 Author chain B； PDBConstruct 120–259； UniProt 667–806

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2xxt
Deposition date deposition_date2010-11-12
Structure title titleCrystal structure of the GluK2 (GluR6) wild-type LBD dimer in complex with kainate
Keywords keywordsTRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2xxt__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2xxt__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2xxt__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）24.95 Å
Rg (electron density)23.66 Å
Total Rg24.57 Å
Atom count3997
Residues496
Excluded volume71980 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2xxt__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd2xxta_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.94 — Periplasmic binding protein-like II
Superfamily Superfamily superfamilyc.94.1 — Periplasmic binding protein-like II
Family Family familyc.94.1.0 — automated matches
Domain ID domain_idd2xxtb_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.94 — Periplasmic binding protein-like II
Superfamily Superfamily superfamilyc.94.1 — Periplasmic binding protein-like II
Family Family familyc.94.1.0 — automated matches

CATH v4.4 (4 domains)

Domain ID domain_id2xxtA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology190 — D-Maltodextrin-Binding Protein; domain 2
Homologous superfamily homologous superfamily10 — Periplasmic binding protein-like II
Domain ID domain_id2xxtA02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology190 — D-Maltodextrin-Binding Protein; domain 2
Homologous superfamily homologous superfamily10 — Periplasmic binding protein-like II
Domain ID domain_id2xxtB01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology190 — D-Maltodextrin-Binding Protein; domain 2
Homologous superfamily homologous superfamily10 — Periplasmic binding protein-like II
Domain ID domain_id2xxtB02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology190 — D-Maltodextrin-Binding Protein; domain 2
Homologous superfamily homologous superfamily10 — Periplasmic binding protein-like II
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7. Citations (1)