2y0s

Crystal structure of Sulfolobus shibatae RNA polymerase in P21 space group

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA-DIRECTED RNA POLYMERASE

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB53_SULSH
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–880； UniProt 1–880 Author chain W； PDBConstruct 1–880； UniProt 1–880

DNA-DIRECTED RNA POLYMERASE

OrganismNot specified

UniProt B8YB55

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB55_SULSH
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 1–1131； UniProt 1–1131 Author chain R； PDBConstruct 1–1131； UniProt 1–1131

;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ;

OrganismNot specified

UniProt B8YB54

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB54_SULSH
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain C； PDBConstruct 1–395； UniProt 1–395 Author chain Y； PDBConstruct 1–395； UniProt 1–395

DNA-DIRECTED RNA POLYMERASE SUBUNIT D

OrganismNot specified

UniProt B8YB56

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB56_SULSH
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain D； PDBConstruct 1–265； UniProt 1–265 Author chain S； PDBConstruct 1–265； UniProt 1–265

RNA POLYMERASE SUBUNIT 4

OrganismNot specified

UniProt B8YB57

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB57_SULSH
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain E； PDBConstruct 1–180； UniProt 1–180 Author chain T； PDBConstruct 1–180； UniProt 1–180

RNA POLYMERASE SUBUNIT 7

OrganismNot specified

UniProt B8YB58

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB58_SULSH
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain F； PDBConstruct 1–113； UniProt 1–113 Author chain U； PDBConstruct 1–113； UniProt 1–113

RNA POLYMERASE SUBUNIT 8

OrganismNot specified

UniProt B8YB59

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB59_SULSH
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain G； PDBConstruct 1–132； UniProt 1–132 Author chain V； PDBConstruct 1–132； UniProt 1–132

DNA-DIRECTED RNA POLYMERASE SUBUNIT H

OrganismNot specified

UniProt B8YB60

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB60_SULSH
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain H； PDBConstruct 1–84； UniProt 1–84 Author chain Z； PDBConstruct 1–84； UniProt 1–84

DNA-DIRECTED RNA POLYMERASE SUBUNIT K

OrganismNot specified

UniProt B8YB61

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB61_SULSH
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain I； PDBConstruct 1–95； UniProt 1–95 Author chain K； PDBConstruct 1–95； UniProt 1–95

RNA POLYMERASE SUBUNIT 13

OrganismNot specified

UniProt B8YB65

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB65_SULSH
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain J； PDBConstruct 1–104； UniProt 1–104 Author chain Q； PDBConstruct 1–104； UniProt 1–104

DNA-DIRECTED RNA POLYMERASE SUBUNIT L

OrganismNot specified

UniProt B8YB62

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB62_SULSH
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain L； PDBConstruct 1–92； UniProt 1–92 Author chain M； PDBConstruct 1–92； UniProt 1–92

DNA-DIRECTED RNA POLYMERASE SUBUNIT N

OrganismNot specified

UniProt B8YB63

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） RNA POLYMERASE SUBUNIT 12 × 1 （B8YB64） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB63_SULSH
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain N； PDBConstruct 1–66； UniProt 1–66 Author chain O； PDBConstruct 1–66； UniProt 1–66

RNA POLYMERASE SUBUNIT 12

OrganismNot specified

UniProt B8YB64

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 13	DNA-DIRECTED RNA POLYMERASE × 1 （B8YB53） DNA-DIRECTED RNA POLYMERASE × 1 （B8YB55） ;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ; × 1 （B8YB54） DNA-DIRECTED RNA POLYMERASE SUBUNIT D × 1 （B8YB56） RNA POLYMERASE SUBUNIT 4 × 1 （B8YB57） RNA POLYMERASE SUBUNIT 7 × 1 （B8YB58） RNA POLYMERASE SUBUNIT 8 × 1 （B8YB59） DNA-DIRECTED RNA POLYMERASE SUBUNIT H × 1 （B8YB60） DNA-DIRECTED RNA POLYMERASE SUBUNIT K × 1 （B8YB61） RNA POLYMERASE SUBUNIT 13 × 1 （B8YB65） DNA-DIRECTED RNA POLYMERASE SUBUNIT L × 1 （B8YB62） DNA-DIRECTED RNA POLYMERASE SUBUNIT N × 1 （B8YB63） ZINC ION × 7 MAGNESIUM ION × 1 FE3-S4 CLUSTER × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B8YB64_SULSH
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain P； PDBConstruct 1–48； UniProt 1–48 Author chain X； PDBConstruct 1–48； UniProt 1–48

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	2y0s
Deposition date deposition_date	2010-12-07
Structure title title	Crystal structure of Sulfolobus shibatae RNA polymerase in P21 space group
Keywords keywords	TRANSFERASE, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, METAL-BINDING; TRANSFERASE
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2y0s__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2y0s__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

2y0s__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	50.99 Å
Rg (electron density)	50.89 Å
Total Rg	51.19 Å
Atom count	26236
Residues	3305
Excluded volume	471560 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2y0s__assembly_1__model_1`	tridecameric （13）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`2y0s__assembly_2__model_1`	tridecameric （13）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (16)

Entity 1 Entity 1 polymer

Description description	DNA-DIRECTED RNA POLYMERASE
Molecular weight formula_weight	99766.5 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,W
Atom count atom_count	52472

MSEKNIKGIKFGILSPDEIRKMSVTAIITPDVYDEDGTPIEGSVMDPRLGVIEPGQKCPTCGNTLGNCPGHFGHIELVRPVIHVGFVKHVYEFLKATCRRCGRVKISEDEIEKYSRIYNAIKKRWPSAARRLTEYVKKTAMKAQVCPHCGEKQFKIKLEKPYNFYEERKEGVAKLTPSDIRERLEKVPESDVEILGYDPTTSRPEWMILTVLPVPPITIRPSIMIESGIRAEDDLTHKLVDIVRINERLKESIDAGAPQLIIEDLWDLLQYHVATYFDNEIPGLPPSKHRSGRPLRTLAQRLKGKEGRFRGNLSGKRVDFSSRTVISPDPNISIDEVGVPEIIARTLTVPERITPWNIEKLRQFVINGPDKWPGANYVIRPDGRRIDLRYVKDRKELASTLAPGYVVERHLTDGDVVLFNRQPSLHRISMMAHRVRVLKGLTFRLNLLVCPPYNADFDGDEMNLHVPQSEEAIAEAKEIMLVHKNIITPRYGGPIIGAAQDYISGAYLLTVKTTLLTKEEAQQILGVADVKIDLGEPAILAPREYYTGKQVVSAFLPKDFNFHGQANVSSGPRLCKNEDCPHDSYVVIKNGILLEGVFDKKAIGNQQPESILHWLIKEYSDEYGKWLMDNLFRVFIRFVELQGFTMRLEDVSLGDDVKKEIYNEIDRAKVEVDNLIQKYKNGELEPIPGRTLEESLENYILDTLDKLRSTAGDIASKYLDPFNFAYVMARTGARGSVLNITQMAAMLGQQSVRGERIKRGYMTRTLPHFKPYDISPEARGFIYSSFRTGLKPTELFFHAAGGREGLVDTAVRTSQSGYMQRRLINALSDLRAEYDGTVRSLYGEVIQVAYGDDGVFPMYSAHGKTVDVNRIFERVVGWKT

Entity 2 Entity 2 polymer

Description description	DNA-DIRECTED RNA POLYMERASE
Molecular weight formula_weight	127582.0 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B,R

MNELSSNLSIDERWKVIEAYFKSKGLVRQHLDSYNDFVRNKLQEIIDEQGEIPTEIPGLKVRLGKIRIGKPRVRESDRGEREISPMEARLRNLTYAAPLWLTMIPVENNIEAEPEEVYIGDLPIMLKSAIDPISQYTLDKLIEIGEDPKDPGGYFIVNGSERVIVTQEDLAPNRVLVDTGKTGSNITHTAKIISSTAGYRVPVTIERLKDGTFHVSFPAVPGKIPFVILMRALGILTDRDIVYAVSLDPEIQNELFPSLEQASSIANVDDALDFIGSRVAIGQKRENRIEKAQQIIDKYFLPHLGTSADDRRKKAYYLAYAISKVIELYLGRREPDDKDHYANKRLRLAGDLFASLFRVAFKAFVKDLTYQLEKSKVRGRKLALKALVRPDIVTERIRHALATGNWVGGRTGVSQLLDRTNWLSMLSHLRRVISSLARGQPNFEARDLHGTQWGRMCPFETPEGPNSGLVKNLALMAQIAVGINEKIVEKTLYEMGVVPVEEVIRRVTEGGEDQNEYLKWSKVILNGRLVGYYRDGEELAKKIRERRRKGEISDEVNVGHIVTDFINEVHVNCDSGRVRRPLIIVSNGNPLVTREDIEKLDSGSITFDDLVRQGKIEYLDAEEEENAYVALEPSDLTPEHTHLEIWSPAILGITASIIPYPEHNQSPRNTYQSAMAKQALGLYAANYQLRTDTRAHLLHYPQRPLVQTRALDIIGYTNRPAGNNAILAVISFTGYNMEDSIIMNRSSVERGMYRSTFFRLYSTEEVKYPGGQEDKIVMPEPGVRGYKGKEYYRLLEDNGVVSPEVEVKGGDVLIGKVSPPRFLQEFKELSPEQAKRDTSIVTRHGEMGIVDLVLITETAEGNKLVKVRVRDLRIPSIGDKFASRHGQKGVIGMLIPQVDMPYTVKGVVPDVILNPHALPSRMTLGQIMEGIAGKYAALSGNIVDATPFYKTPIEQLQNEILKYGYLPDATEVTYDGRTGQKIKSRIYFGVVYYQKLHHMVADKIHARARGPVQILTRQPTEGRAREGGLRFGEMERDCLIGFGTAMLLKDRLLDNSDRTTIYVCDQCGYIGWYDKNKNKYVCPIHGDKSNLFPVTVSYAFKLLIQELMSMIISPRLILEDRVGLSGGKGNE

Entity 3 Entity 3 polymer

Description description	;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ;
Molecular weight formula_weight	43792.8 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C,Y

MENVIDEKDKSYLEEKVKQASNILPQKIVEDLKNLISNKEVLVTRDEIDKIFDLAIKEYSEGLIAPGEAIGIVAAQSVGEPGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTPMMTIYLTDEYKHDKEKALEVARKLEYTKIENVVSSTSIDIASMSIILQLDNEMLKDKGVTVDDVKKAINRLKLGEFVIDESEGNTLNISFANIDSIAALFKLRDKILNTKIKGIKGIKRAIVQKKGDEYIILTDGSNLSGVLSVKGVDIAKVETNNIREIEEVFGIEAAREIIIREISKVLAEQGLDVDMRHILLVADVMTRTGVVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAARGDVEEFKGVVENIIIGHPIKLGTGMVELTMRPILR

Entity 4 Entity 4 polymer

Description description	DNA-DIRECTED RNA POLYMERASE SUBUNIT D
Molecular weight formula_weight	30179.1 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D,S

MSINLLHKDDKRIDLVFEGYPLEFVNAIRRAAMLYVPVMSIDDVYFIENNSPLYDEILAHRLALIPFTSEEALDTYRWPEECIDCTENCEKCYTKIYIEAEALNEPKMLYSKDIKSEDPSIVPISGDIPIVLLGANQKISLEARLRLGYGKEHAKFIPVSLAIVRYYPKVEILGNCEKGATVCPEGVFELKDGKLSVKNELACTLCEECLRYCNGLIRISSVEDKYILELESVGSLKPERILLEAGKSIIRKIEELEKKLVEVIK

Entity 5 Entity 5 polymer

Description description	RNA POLYMERASE SUBUNIT 4
Molecular weight formula_weight	20328.7 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E,T

MYKLIKARSIVRIPPNEFGKPLNEIALNELRQQYQEKILKDLGLVLAILNVKTSEEGMLVFGDGATYHEVEFDMITYVPVVQEVVEGEVLQVDNYGVFVNLGPMDGLVHISQITDDTLKYDNVRGIIFGEKSKKVIQKGDKVRARVISVASTVTGRLPRIALTMRQPYLGKLEWITQAKK

Entity 6 Entity 6 polymer

Description description	RNA POLYMERASE SUBUNIT 7
Molecular weight formula_weight	12822.6 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F,U

MSSVYIVEEHYIPYSVAKKLLSDVIKSGSSSNLLQRTYDYLNSVEKCDAESAQKVVEELSSIISREDVRAVLASICPITPDEVRSILIMDSNRTYTSEDIQKIIDIIRKYIKS

Entity 7 Entity 7 polymer

Description description	RNA POLYMERASE SUBUNIT 8
Molecular weight formula_weight	15139.5 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G,V

MMESKAQEIILSCEINSIERGSLKNLSIIHMSCNDFNISFDIIDSINIFSQKEKVKAFISKNRLSYTNDDFCGHGYIVTELKDSSSNNGNRYITIISLFGLLVKIISNKESFLKIHQLNVMDHIYFCVKKNT

Entity 8 Entity 8 polymer

Description description	DNA-DIRECTED RNA POLYMERASE SUBUNIT H
Molecular weight formula_weight	9688.3 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H,Z

MRGSSNRKIDPRIHYLVPKHEVLSIDEAYKILKELGIRPEQLPWIRASDPVARSINAKPGDIIRIIRKSQLYGEVVSYRYVISG

Entity 9 Entity 9 polymer

Description description	DNA-DIRECTED RNA POLYMERASE SUBUNIT K
Molecular weight formula_weight	10729.5 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I,K

MGLERDGILSQDLHFNEVFVSLWQNKLTRYEIARVISARALQLAMGAPALIDINNISSTDVISIAEEEFKRGVLPITIRRRLPNGKIILLSLRKS

Entity 10 Entity 10 polymer

Description description	RNA POLYMERASE SUBUNIT 13
Molecular weight formula_weight	12169.6 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J,Q

MVSGMSTEEEKEGTNDEEVSEEREVEETSEEEFPKLSIQNIELLMKNTEIWDNLLNGKISVDEAKRLFEDNYKDYEKRDSRRKAKKAASKKVKKTKKKEKSVEG

Entity 11 Entity 11 polymer

Description description	DNA-DIRECTED RNA POLYMERASE SUBUNIT L
Molecular weight formula_weight	10211.8 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L,M

MEIKILKSESNYLELEIEGEDHTLGNLIAGTLRKISGVSFASYYQPHPLTDKIIVKILTDGSIAPKDALLKAIETVRVMASHYIDEIKGLTK

Entity 12 Entity 12 polymer

Description description	DNA-DIRECTED RNA POLYMERASE SUBUNIT N
Molecular weight formula_weight	7617.1 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N,O

MMIPIRCFTCGSLIADKWQPFITRVNAGENPGKVLDDLGVKRYCCRRMLLSHIDIISEVIHYTRPI

Entity 13 Entity 13 polymer

Description description	RNA POLYMERASE SUBUNIT 12
Molecular weight formula_weight	5607.0 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	P,X

MAVYRCGKCWKTFTDEQLKVLPGVRCPYCGYKIIFMVRKPTIKIVKAI

Entity 14 Entity 14 non-polymer

Description description	ZINC ION
Molecular weight formula_weight	65.4 kDa
Source method src_method	syn
Copy count entity_count	14

Entity 15 Entity 15 non-polymer

Description description	MAGNESIUM ION
Molecular weight formula_weight	24.3 kDa
Source method src_method	syn
Copy count entity_count	2

Entity 16 Entity 16 non-polymer

Description description	FE3-S4 CLUSTER
Molecular weight formula_weight	295.8 kDa
Source method src_method	syn
Copy count entity_count	2

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6. Fold Classification (SCOP + CATH) 54 domains

CATH v4.4 (54 domains)

Domain ID domain_id	2y0sA02
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	40 — Barwin-like endoglucanases
Homologous superfamily homologous superfamily	20 —

Domain ID domain_id	2y0sA03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	180 — RNA polymerase ii

Domain ID domain_id	2y0sA04
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily	1950 —

Domain ID domain_id	2y0sA05
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	320 — Dihydrolipoamide Transferase
Homologous superfamily homologous superfamily	40 —

Domain ID domain_id	2y0sA06
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	40 — Immunoglobulin-like
Homologous superfamily homologous superfamily	2940 —

Domain ID domain_id	2y0sA07
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	132 — Topoisomerase I; Chain A, domain 4
Homologous superfamily homologous superfamily	30 — RNA polymerase Rpb1 funnel domain

Domain ID domain_id	2y0sA08
Class class	6 — Special
Architecture architecture	10 — Helix non-globular
Topology topology	250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	2940 —

Domain ID domain_id	2y0sA09
Class class	6 — Special
Architecture architecture	20 — Other non-globular
Topology topology	50 — N-terminal domain of TfIIb
Homologous superfamily homologous superfamily	80 —

Domain ID domain_id	2y0sB04
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1110 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3
Homologous superfamily homologous superfamily	10 — RNA polymerase Rpb2, domain 2

Domain ID domain_id	2y0sB05
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1070 — Hypothetical Protein Ta0175; Chain: A, domain 2
Homologous superfamily homologous superfamily	20 —

Domain ID domain_id	2y0sB06
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	270 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6
Homologous superfamily homologous superfamily	10 — DNA-directed RNA polymerase, subunit 2, domain 6

Domain ID domain_id	2y0sB07
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily	150 — RNA polymerase II, Rpb2 subunit, wall domain

Domain ID domain_id	2y0sB08
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1800 — DCoH-like
Homologous superfamily homologous superfamily	10 — RNA polymerase alpha subunit dimerisation domain

Domain ID domain_id	2y0sC02
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily	390 —

Domain ID domain_id	2y0sD01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily	10 — RNA polymerase, RBP11-like subunit

Domain ID domain_id	2y0sD02
Class class	2 — Mainly Beta
Architecture architecture	170 — Beta Complex
Topology topology	120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
Homologous superfamily homologous superfamily	12 — DNA-directed RNA polymerase, insert domain

Domain ID domain_id	2y0sD03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	20 —

Domain ID domain_id	2y0sE01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	120 — RNA polymerase Rpb7-like, N-terminal domain

Domain ID domain_id	2y0sE02
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily	140 — Nucleic acid-binding proteins

Domain ID domain_id	2y0sF01
Class class	6 — Special
Architecture architecture	10 — Helix non-globular
Topology topology	140 — Helix Hairpins
Homologous superfamily homologous superfamily	930 —

Domain ID domain_id	2y0sF02
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily	80 — HRDC domain

Domain ID domain_id	2y0sG00
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily	140 — Nucleic acid-binding proteins

Domain ID domain_id	2y0sH00
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	940 — Eukaryotic RPB6 RNA polymerase subunit
Homologous superfamily homologous superfamily	20 — RPB5-like RNA polymerase subunit

Domain ID domain_id	2y0sI00
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	940 — Eukaryotic RPB6 RNA polymerase subunit
Homologous superfamily homologous superfamily	10 — RNA polymerase subunit, RPB6/omega

Domain ID domain_id	2y0sK00
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	940 — Eukaryotic RPB6 RNA polymerase subunit
Homologous superfamily homologous superfamily	10 — RNA polymerase subunit, RPB6/omega

Domain ID domain_id	2y0sL00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily	10 — RNA polymerase, RBP11-like subunit

Domain ID domain_id	2y0sM00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily	10 — RNA polymerase, RBP11-like subunit

Domain ID domain_id	2y0sN00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily	60 — Homeodomain-like

Domain ID domain_id	2y0sO00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily	60 — Homeodomain-like

Domain ID domain_id	2y0sP00
Class class	2 — Mainly Beta
Architecture architecture	20 — Single Sheet
Topology topology	28 — Rubrerythrin, domain 2
Homologous superfamily homologous superfamily	30 — RNA polymerase ii, chain L

Domain ID domain_id	2y0sR04
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1110 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3
Homologous superfamily homologous superfamily	10 — RNA polymerase Rpb2, domain 2

Domain ID domain_id	2y0sR05
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1070 — Hypothetical Protein Ta0175; Chain: A, domain 2
Homologous superfamily homologous superfamily	20 —

Domain ID domain_id	2y0sR06
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	270 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6
Homologous superfamily homologous superfamily	10 — DNA-directed RNA polymerase, subunit 2, domain 6

Domain ID domain_id	2y0sR07
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily	150 — RNA polymerase II, Rpb2 subunit, wall domain

Domain ID domain_id	2y0sR08
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1800 — DCoH-like
Homologous superfamily homologous superfamily	10 — RNA polymerase alpha subunit dimerisation domain

Domain ID domain_id	2y0sS01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily	10 — RNA polymerase, RBP11-like subunit

Domain ID domain_id	2y0sS02
Class class	2 — Mainly Beta
Architecture architecture	170 — Beta Complex
Topology topology	120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
Homologous superfamily homologous superfamily	12 — DNA-directed RNA polymerase, insert domain

Domain ID domain_id	2y0sS03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	20 —

Domain ID domain_id	2y0sT01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	120 — RNA polymerase Rpb7-like, N-terminal domain

Domain ID domain_id	2y0sT02
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily	140 — Nucleic acid-binding proteins

Domain ID domain_id	2y0sU01
Class class	6 — Special
Architecture architecture	10 — Helix non-globular
Topology topology	140 — Helix Hairpins
Homologous superfamily homologous superfamily	930 —

Domain ID domain_id	2y0sU02
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily	80 — HRDC domain

Domain ID domain_id	2y0sV00
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily	140 — Nucleic acid-binding proteins

Domain ID domain_id	2y0sW02
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	40 — Barwin-like endoglucanases
Homologous superfamily homologous superfamily	20 —

Domain ID domain_id	2y0sW03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	180 — RNA polymerase ii

Domain ID domain_id	2y0sW04
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily	1950 —

Domain ID domain_id	2y0sW05
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	320 — Dihydrolipoamide Transferase
Homologous superfamily homologous superfamily	40 —

Domain ID domain_id	2y0sW06
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	40 — Immunoglobulin-like
Homologous superfamily homologous superfamily	2940 —

Domain ID domain_id	2y0sW07
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	132 — Topoisomerase I; Chain A, domain 4
Homologous superfamily homologous superfamily	30 — RNA polymerase Rpb1 funnel domain

Domain ID domain_id	2y0sW08
Class class	6 — Special
Architecture architecture	10 — Helix non-globular
Topology topology	250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	2940 —

Domain ID domain_id	2y0sW09
Class class	6 — Special
Architecture architecture	20 — Other non-globular
Topology topology	50 — N-terminal domain of TfIIb
Homologous superfamily homologous superfamily	80 —

Domain ID domain_id	2y0sX00
Class class	2 — Mainly Beta
Architecture architecture	20 — Single Sheet
Topology topology	28 — Rubrerythrin, domain 2
Homologous superfamily homologous superfamily	30 — RNA polymerase ii, chain L

Domain ID domain_id	2y0sY02
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily	390 —

Domain ID domain_id	2y0sZ00
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	940 — Eukaryotic RPB6 RNA polymerase subunit
Homologous superfamily homologous superfamily	20 — RPB5-like RNA polymerase subunit

▶

Unit-cell length a length_a	129.330 Å
Unit-cell length b length_b	195.909 Å
Unit-cell length c length_c	212.451 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	105.73 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	4

Space group space_group	P 1 21 1
Space-group number int_tables_number	4
Crystal system crystal_system	—

Resolution resolution	3.800 Å
Low-resolution limit resolution_low	29.858 Å
R factor r_factor	0.3024
R_work r_work	0.2997
R_free r_free	0.3539

Crystal structure of Sulfolobus shibatae RNA polymerase in P21 space group

1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA-DIRECTED RNA POLYMERASE

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASE

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

;DNA-DIRECTED RNA POLYMERASE SUBUNIT A'' ;

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASE SUBUNIT D

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

RNA POLYMERASE SUBUNIT 4

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

RNA POLYMERASE SUBUNIT 7

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

RNA POLYMERASE SUBUNIT 8

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASE SUBUNIT H

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASE SUBUNIT K

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

RNA POLYMERASE SUBUNIT 13

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer