Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid × 1 water × 2 | 与蛋白数一致 |
| 2 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid × 1 water × 2 | 与蛋白数一致 |
| UniProt名称 | PPARG_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 5–286； UniProt 223–504 作者链 B； PDB构建体 5–286； UniProt 223–504 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 3b3k |
| 沉积日期 deposition_date | 2007-10-22 |
| 结构标题 title | Crystal structure of the complex between PPARgamma and the full agonist LT175 |
| 关键词 keywords | ;bundle of alpha-helices, small four-strnded beta-sheet, Activator, Alternative splicing, Diabetes mellitus, Disease mutation, DNA-binding, Metal-binding, Nucleus, Obesity, Phosphorylation, Polymorphism, Receptor, Transcription, Transcription regulation, Zinc, Zinc-finger ;; TRANSCRIPTION |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 26.87 Å |
| Rg（电子密度） | 25.82 Å |
| 总 Rg | 26.77 Å |
| 原子数 | 4356 |
| 残基数 | 540 |
| 排除体积 | 79028 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d3b3ka_ |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.123 — Nuclear receptor ligand-binding domain |
| 超家族 Superfamily superfamily | a.123.1 — Nuclear receptor ligand-binding domain |
| 家族 Family family | a.123.1.1 — Nuclear receptor ligand-binding domain |
| 结构域编号 domain_id | d3b3kb_ |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.123 — Nuclear receptor ligand-binding domain |
| 超家族 Superfamily superfamily | a.123.1 — Nuclear receptor ligand-binding domain |
| 家族 Family family | a.123.1.1 — Nuclear receptor ligand-binding domain |
| 结构域编号 domain_id | 3b3kA00 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 565 — Retinoid X Receptor |
| 同源超家族 H-superfamily homologous superfamily | 10 — Retinoid X Receptor |
| 结构域编号 domain_id | 3b3kB00 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 565 — Retinoid X Receptor |
| 同源超家族 H-superfamily homologous superfamily | 10 — Retinoid X Receptor |