3cmt

Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures

Method: X-RAY DIFFRACTION

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Protein recA

Escherichia coli

UniProt P0A7G6

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 单体 蛋白 1 DNA 2 ;DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DCP*DTP*DTP*DTP*DT)-3') ; × 1 ;DNA (5'-D(P*DGP*DGP*DTP*DGP*DGP*DG)-3') ; × 1 MAGNESIUM ION × 5 TETRAFLUOROALUMINATE ION × 5 ADENOSINE-5'-DIPHOSPHATE × 5 与全部聚合物一致
2 蛋白–DNA 单体 蛋白 1 DNA 2 ;DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DCP*DTP*DTP*DTP*DT)-3') ; × 1 ;DNA (5'-D(P*DGP*DGP*DTP*DGP*DGP*DG)-3') ; × 1 MAGNESIUM ION × 5 TETRAFLUOROALUMINATE ION × 5 ADENOSINE-5'-DIPHOSPHATE × 5 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 RECA_ECOLI
Isoform
PDB实体 3
链与序列区间 作者链 A; PDB构建体 5–309; UniProt 31–335 作者链 A; PDB构建体 325–658; UniProt 2–335 作者链 A; PDB构建体 674–1007; UniProt 2–335 作者链 A; PDB构建体 1024–1357; UniProt 2–335 作者链 A; PDB构建体 1373–1706; UniProt 2–335 作者链 D; PDB构建体 5–309; UniProt 31–335 作者链 D; PDB构建体 325–658; UniProt 2–335 作者链 D; PDB构建体 674–1007; UniProt 2–335 作者链 D; PDB构建体 1024–1357; UniProt 2–335 作者链 D; PDB构建体 1373–1706; UniProt 2–335

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

2. 结构基本信息 2. Structure Basics

条目编号 entry_id3cmt
沉积日期 deposition_date2008-03-24
结构标题 titleMechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
关键词 keywords;homologous recombination, ATP-binding, Cytoplasm, DNA damage, DNA recombination, DNA repair, DNA-binding, Nucleotide-binding, SOS response, Stress response, recombination-DNA COMPLEX ;; recombination/DNA
实验方法 methodX-RAY DIFFRACTION

3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

3cmt__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

3cmt__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

3cmt__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)41.18 Å
Rg(电子密度)41.49 Å
总 Rg41.47 Å
原子数12656
残基数1627
排除体积225100 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 3cmt__assembly_1__model_1 trimeric (3) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 3cmt__assembly_2__model_1 trimeric (3) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合物信息 Entities & Polymers (6)

6. 折叠分类 (SCOP + CATH) 20 domains

CATH v4.4 (20 domains)

结构域编号 domain_id3cmtA01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cmtA02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology250 — Rec A Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — RecA protein, C-terminal domain
结构域编号 domain_id3cmtA03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cmtA04
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology250 — Rec A Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — RecA protein, C-terminal domain
结构域编号 domain_id3cmtA05
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cmtA06
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology250 — Rec A Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — RecA protein, C-terminal domain
结构域编号 domain_id3cmtA07
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cmtA08
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology250 — Rec A Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — RecA protein, C-terminal domain
结构域编号 domain_id3cmtA09
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cmtA10
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology250 — Rec A Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — RecA protein, C-terminal domain
结构域编号 domain_id3cmtD01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cmtD02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology250 — Rec A Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — RecA protein, C-terminal domain
结构域编号 domain_id3cmtD03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cmtD04
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology250 — Rec A Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — RecA protein, C-terminal domain
结构域编号 domain_id3cmtD05
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cmtD06
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology250 — Rec A Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — RecA protein, C-terminal domain
结构域编号 domain_id3cmtD07
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cmtD08
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology250 — Rec A Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — RecA protein, C-terminal domain
结构域编号 domain_id3cmtD09
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cmtD10
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology250 — Rec A Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — RecA protein, C-terminal domain

7. 引用文献 (1)