3d54

Structure of PurLQS from Thermotoga maritima

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Phosphoribosylformylglycinamidine synthase II

Thermotoga maritima

UniProt Q9X0X3

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 4 Formylglycinamide ribonucleotide amidotransferase × 2 (Q9X0X1) Phosphoribosylformylglycinamidine synthase 1 × 1 (Q9X0X2) SODIUM ION × 1 ADENOSINE-5'-DIPHOSPHATE × 1 与蛋白数一致
2 蛋白异源复合物 异源复合物 蛋白 4 Formylglycinamide ribonucleotide amidotransferase × 2 (Q9X0X1) Phosphoribosylformylglycinamidine synthase 1 × 1 (Q9X0X2) SODIUM ION × 1 ADENOSINE-5'-DIPHOSPHATE × 1 与蛋白数一致
3 蛋白异源复合物 异源复合物 蛋白 4 Formylglycinamide ribonucleotide amidotransferase × 2 (Q9X0X1) Phosphoribosylformylglycinamidine synthase 1 × 1 (Q9X0X2) SODIUM ION × 1 ADENOSINE-5'-DIPHOSPHATE × 1 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PURL_THEMA
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 27–629; UniProt 1–603 作者链 E; PDB构建体 27–629; UniProt 1–603 作者链 I; PDB构建体 27–629; UniProt 1–603

Formylglycinamide ribonucleotide amidotransferase

Thermotoga maritima

UniProt Q9X0X1

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 4 Phosphoribosylformylglycinamidine synthase II × 1 (Q9X0X3) Phosphoribosylformylglycinamidine synthase 1 × 1 (Q9X0X2) SODIUM ION × 1 ADENOSINE-5'-DIPHOSPHATE × 1 与蛋白数一致
2 蛋白异源复合物 异源复合物 蛋白 4 Phosphoribosylformylglycinamidine synthase II × 1 (Q9X0X3) Phosphoribosylformylglycinamidine synthase 1 × 1 (Q9X0X2) SODIUM ION × 1 ADENOSINE-5'-DIPHOSPHATE × 1 与蛋白数一致
3 蛋白异源复合物 异源复合物 蛋白 4 Phosphoribosylformylglycinamidine synthase II × 1 (Q9X0X3) Phosphoribosylformylglycinamidine synthase 1 × 1 (Q9X0X2) SODIUM ION × 1 ADENOSINE-5'-DIPHOSPHATE × 1 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 Q9X0X1_THEMA
Isoform —
PDB实体 2
链与序列区间 作者链 B; PDB构建体 1–82; UniProt 1–82 作者链 C; PDB构建体 1–82; UniProt 1–82 作者链 F; PDB构建体 1–82; UniProt 1–82 作者链 G; PDB构建体 1–82; UniProt 1–82 作者链 J; PDB构建体 1–82; UniProt 1–82 作者链 K; PDB构建体 1–82; UniProt 1–82

Phosphoribosylformylglycinamidine synthase 1

Thermotoga maritima

UniProt Q9X0X2

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 4 Phosphoribosylformylglycinamidine synthase II × 1 (Q9X0X3) Formylglycinamide ribonucleotide amidotransferase × 2 (Q9X0X1) SODIUM ION × 1 ADENOSINE-5'-DIPHOSPHATE × 1 与蛋白数一致
2 蛋白异源复合物 异源复合物 蛋白 4 Phosphoribosylformylglycinamidine synthase II × 1 (Q9X0X3) Formylglycinamide ribonucleotide amidotransferase × 2 (Q9X0X1) SODIUM ION × 1 ADENOSINE-5'-DIPHOSPHATE × 1 与蛋白数一致
3 蛋白异源复合物 异源复合物 蛋白 4 Phosphoribosylformylglycinamidine synthase II × 1 (Q9X0X3) Formylglycinamide ribonucleotide amidotransferase × 2 (Q9X0X1) SODIUM ION × 1 ADENOSINE-5'-DIPHOSPHATE × 1 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PURQ_THEMA
Isoform —
PDB实体 3
链与序列区间 作者链 D; PDB构建体 1–213; UniProt 1–213 作者链 H; PDB构建体 1–213; UniProt 1–213 作者链 L; PDB构建体 1–213; UniProt 1–213

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id3d54
沉积日期 deposition_date2008-05-15
结构标题 titleStructure of PurLQS from Thermotoga maritima
关键词 keywords;alpha-beta structure, ATP-binding, Ligase, Nucleotide-binding, Purine biosynthesis, Glutamine amidotransferase, LIGASE-UNKNOWN FUNCTION COMPLEX ;; LIGASE
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

3d54__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

3d54__assembly_2__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

3d54__assembly_2__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)29.93 Å
Rg(电子密度)29.09 Å
总 Rg29.95 Å
原子数7528
残基数958
排除体积134830 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 3d54__assembly_1__model_1 tetrameric (4) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 3d54__assembly_2__model_1 tetrameric (4) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 3d54__assembly_3__model_1 tetrameric (4) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (5)

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6. 折叠分类 (SCOP + CATH) 33 domains

SCOP 2.08 (12 domains)

结构域编号 domain_idd3d54a1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.79 — Bacillus chorismate mutase-like
超家族 Superfamily superfamilyd.79.4 — PurM N-terminal domain-like
家族 Family familyd.79.4.1 — PurM N-terminal domain-like
结构域编号 domain_idd3d54a2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.79 — Bacillus chorismate mutase-like
超家族 Superfamily superfamilyd.79.4 — PurM N-terminal domain-like
家族 Family familyd.79.4.1 — PurM N-terminal domain-like
结构域编号 domain_idd3d54a3
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.139 — PurM C-terminal domain-like
超家族 Superfamily superfamilyd.139.1 — PurM C-terminal domain-like
家族 Family familyd.139.1.1 — PurM C-terminal domain-like
结构域编号 domain_idd3d54a4
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.139 — PurM C-terminal domain-like
超家族 Superfamily superfamilyd.139.1 — PurM C-terminal domain-like
家族 Family familyd.139.1.1 — PurM C-terminal domain-like
结构域编号 domain_idd3d54e1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.79 — Bacillus chorismate mutase-like
超家族 Superfamily superfamilyd.79.4 — PurM N-terminal domain-like
家族 Family familyd.79.4.1 — PurM N-terminal domain-like
结构域编号 domain_idd3d54e2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.79 — Bacillus chorismate mutase-like
超家族 Superfamily superfamilyd.79.4 — PurM N-terminal domain-like
家族 Family familyd.79.4.1 — PurM N-terminal domain-like
结构域编号 domain_idd3d54e3
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.139 — PurM C-terminal domain-like
超家族 Superfamily superfamilyd.139.1 — PurM C-terminal domain-like
家族 Family familyd.139.1.1 — PurM C-terminal domain-like
结构域编号 domain_idd3d54e4
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.139 — PurM C-terminal domain-like
超家族 Superfamily superfamilyd.139.1 — PurM C-terminal domain-like
家族 Family familyd.139.1.1 — PurM C-terminal domain-like
结构域编号 domain_idd3d54i1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.79 — Bacillus chorismate mutase-like
超家族 Superfamily superfamilyd.79.4 — PurM N-terminal domain-like
家族 Family familyd.79.4.1 — PurM N-terminal domain-like
结构域编号 domain_idd3d54i2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.79 — Bacillus chorismate mutase-like
超家族 Superfamily superfamilyd.79.4 — PurM N-terminal domain-like
家族 Family familyd.79.4.1 — PurM N-terminal domain-like
结构域编号 domain_idd3d54i3
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.139 — PurM C-terminal domain-like
超家族 Superfamily superfamilyd.139.1 — PurM C-terminal domain-like
家族 Family familyd.139.1.1 — PurM C-terminal domain-like
结构域编号 domain_idd3d54i4
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.139 — PurM C-terminal domain-like
超家族 Superfamily superfamilyd.139.1 — PurM C-terminal domain-like
家族 Family familyd.139.1.1 — PurM C-terminal domain-like

CATH v4.4 (21 domains)

结构域编号 domain_id3d54A01
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology650 — Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2
同源超家族 H-superfamily homologous superfamily10 — PurM-like C-terminal domain
结构域编号 domain_id3d54A02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
同源超家族 H-superfamily homologous superfamily10 — PurM-like, N-terminal domain
结构域编号 domain_id3d54A03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
同源超家族 H-superfamily homologous superfamily10 — PurM-like, N-terminal domain
结构域编号 domain_id3d54A04
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily1670 — Formylglycinamide ribonucleotide amidotransferase, C-terminal domain
结构域编号 domain_id3d54B00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1280 — Mth169; Chain: A ,
同源超家族 H-superfamily homologous superfamily10 — Phosphoribosylformylglycinamidine synthase subunit PurS
结构域编号 domain_id3d54C00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1280 — Mth169; Chain: A ,
同源超家族 H-superfamily homologous superfamily10 — Phosphoribosylformylglycinamidine synthase subunit PurS
结构域编号 domain_id3d54D00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily880 — Class I glutamine amidotransferase (GATase) domain
结构域编号 domain_id3d54E01
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology650 — Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2
同源超家族 H-superfamily homologous superfamily10 — PurM-like C-terminal domain
结构域编号 domain_id3d54E02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
同源超家族 H-superfamily homologous superfamily10 — PurM-like, N-terminal domain
结构域编号 domain_id3d54E03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
同源超家族 H-superfamily homologous superfamily10 — PurM-like, N-terminal domain
结构域编号 domain_id3d54E04
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily1670 — Formylglycinamide ribonucleotide amidotransferase, C-terminal domain
结构域编号 domain_id3d54F00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1280 — Mth169; Chain: A ,
同源超家族 H-superfamily homologous superfamily10 — Phosphoribosylformylglycinamidine synthase subunit PurS
结构域编号 domain_id3d54G00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1280 — Mth169; Chain: A ,
同源超家族 H-superfamily homologous superfamily10 — Phosphoribosylformylglycinamidine synthase subunit PurS
结构域编号 domain_id3d54H00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily880 — Class I glutamine amidotransferase (GATase) domain
结构域编号 domain_id3d54I01
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology650 — Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2
同源超家族 H-superfamily homologous superfamily10 — PurM-like C-terminal domain
结构域编号 domain_id3d54I02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
同源超家族 H-superfamily homologous superfamily10 — PurM-like, N-terminal domain
结构域编号 domain_id3d54I03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
同源超家族 H-superfamily homologous superfamily10 — PurM-like, N-terminal domain
结构域编号 domain_id3d54I04
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily1670 — Formylglycinamide ribonucleotide amidotransferase, C-terminal domain
结构域编号 domain_id3d54J00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1280 — Mth169; Chain: A ,
同源超家族 H-superfamily homologous superfamily10 — Phosphoribosylformylglycinamidine synthase subunit PurS
结构域编号 domain_id3d54K00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1280 — Mth169; Chain: A ,
同源超家族 H-superfamily homologous superfamily10 — Phosphoribosylformylglycinamidine synthase subunit PurS
结构域编号 domain_id3d54L00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily880 — Class I glutamine amidotransferase (GATase) domain
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7. 引用文献 (1)