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3dxj

Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA-directed RNA polymerase subunit alpha; CHAIN A, B, K, L

OrganismNot specified

UniProt Q5SHR6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M × 1 （Q8RQE9） BACTERIAL RNA POLYMERASE BETA-PRIME SUBUNIT; CHAIN D, N × 1 （Q8RQE8） BACTERIAL RNA POLYMERASE OMEGA SUBUNIT; CHAIN E, O × 1 （Q8RQE7） RNA polymerase pricipal sigma factor (RpoD); CHAIN F, P × 1 （Q5SKW1） PHOSPHATE ION × 2 MAGNESIUM ION × 2 (4S)-2-METHYL-2,4-PENTANEDIOL × 2 ZINC ION × 2 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate × 1 water × 5 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M × 1 （Q8RQE9） BACTERIAL RNA POLYMERASE BETA-PRIME SUBUNIT; CHAIN D, N × 1 （Q8RQE8） BACTERIAL RNA POLYMERASE OMEGA SUBUNIT; CHAIN E, O × 1 （Q8RQE7） RNA polymerase pricipal sigma factor (RpoD); CHAIN F, P × 1 （Q5SKW1） MAGNESIUM ION × 1 (4S)-2-METHYL-2,4-PENTANEDIOL × 1 ZINC ION × 2 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1zyr 1zyr 2a6e 2a6e 2a6h 2a6h 2cw0 2cw0 2o5i 2o5i 2o5j 2o5j

95 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name RPOA_THET8
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–315； UniProt 1–315 Author chain B； PDBConstruct 1–315； UniProt 1–315 Author chain K； PDBConstruct 1–315； UniProt 1–315 Author chain L； PDBConstruct 1–315； UniProt 1–315

BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M

OrganismNot specified

UniProt Q8RQE9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 DNA-directed RNA polymerase subunit alpha; CHAIN A, B, K, L × 2 （Q5SHR6） BACTERIAL RNA POLYMERASE BETA-PRIME SUBUNIT; CHAIN D, N × 1 （Q8RQE8） BACTERIAL RNA POLYMERASE OMEGA SUBUNIT; CHAIN E, O × 1 （Q8RQE7） RNA polymerase pricipal sigma factor (RpoD); CHAIN F, P × 1 （Q5SKW1） PHOSPHATE ION × 2 MAGNESIUM ION × 2 (4S)-2-METHYL-2,4-PENTANEDIOL × 2 ZINC ION × 2 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate × 1 water × 5 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 DNA-directed RNA polymerase subunit alpha; CHAIN A, B, K, L × 2 （Q5SHR6） BACTERIAL RNA POLYMERASE BETA-PRIME SUBUNIT; CHAIN D, N × 1 （Q8RQE8） BACTERIAL RNA POLYMERASE OMEGA SUBUNIT; CHAIN E, O × 1 （Q8RQE7） RNA polymerase pricipal sigma factor (RpoD); CHAIN F, P × 1 （Q5SKW1） MAGNESIUM ION × 1 (4S)-2-METHYL-2,4-PENTANEDIOL × 1 ZINC ION × 2 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1smy 1smy 1zyr 1zyr 2a68 2a68 2a69 2a69 2a6e 2a6e 2a6h 2a6h

147 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name RPOB_THET8
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C； PDBConstruct 1–1119； UniProt 1–1119 Author chain M； PDBConstruct 1–1119； UniProt 1–1119

BACTERIAL RNA POLYMERASE BETA-PRIME SUBUNIT; CHAIN D, N

OrganismNot specified

UniProt Q8RQE8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 DNA-directed RNA polymerase subunit alpha; CHAIN A, B, K, L × 2 （Q5SHR6） BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M × 1 （Q8RQE9） BACTERIAL RNA POLYMERASE OMEGA SUBUNIT; CHAIN E, O × 1 （Q8RQE7） RNA polymerase pricipal sigma factor (RpoD); CHAIN F, P × 1 （Q5SKW1） PHOSPHATE ION × 2 MAGNESIUM ION × 2 (4S)-2-METHYL-2,4-PENTANEDIOL × 2 ZINC ION × 2 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate × 1 water × 5 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 DNA-directed RNA polymerase subunit alpha; CHAIN A, B, K, L × 2 （Q5SHR6） BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M × 1 （Q8RQE9） BACTERIAL RNA POLYMERASE OMEGA SUBUNIT; CHAIN E, O × 1 （Q8RQE7） RNA polymerase pricipal sigma factor (RpoD); CHAIN F, P × 1 （Q5SKW1） MAGNESIUM ION × 1 (4S)-2-METHYL-2,4-PENTANEDIOL × 1 ZINC ION × 2 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1smy 1smy 1zyr 1zyr 2a68 2a68 2a69 2a69 2a6e 2a6e 2a6h 2a6h

133 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name RPOC_THET8
Isoform —
PDB entities 3
Chains and sequence ranges Author chain D； PDBConstruct 1–1524； UniProt 1–1524 Author chain N； PDBConstruct 1–1524； UniProt 1–1524

BACTERIAL RNA POLYMERASE OMEGA SUBUNIT; CHAIN E, O

OrganismNot specified

UniProt Q8RQE7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 DNA-directed RNA polymerase subunit alpha; CHAIN A, B, K, L × 2 （Q5SHR6） BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M × 1 （Q8RQE9） BACTERIAL RNA POLYMERASE BETA-PRIME SUBUNIT; CHAIN D, N × 1 （Q8RQE8） RNA polymerase pricipal sigma factor (RpoD); CHAIN F, P × 1 （Q5SKW1） PHOSPHATE ION × 2 MAGNESIUM ION × 2 (4S)-2-METHYL-2,4-PENTANEDIOL × 2 ZINC ION × 2 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate × 1 water × 5 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 DNA-directed RNA polymerase subunit alpha; CHAIN A, B, K, L × 2 （Q5SHR6） BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M × 1 （Q8RQE9） BACTERIAL RNA POLYMERASE BETA-PRIME SUBUNIT; CHAIN D, N × 1 （Q8RQE8） RNA polymerase pricipal sigma factor (RpoD); CHAIN F, P × 1 （Q5SKW1） MAGNESIUM ION × 1 (4S)-2-METHYL-2,4-PENTANEDIOL × 1 ZINC ION × 2 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1zyr 1zyr 2a6e 2a6e 2a6h 2a6h 2be5 2be5 2cw0 2cw0 2o5i 2o5i

113 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name RPOZ_THET8
Isoform —
PDB entities 4
Chains and sequence ranges Author chain E； PDBConstruct 1–99； UniProt 1–99 Author chain O； PDBConstruct 1–99； UniProt 1–99

RNA polymerase pricipal sigma factor (RpoD); CHAIN F, P

OrganismNot specified

UniProt Q5SKW1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 DNA-directed RNA polymerase subunit alpha; CHAIN A, B, K, L × 2 （Q5SHR6） BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M × 1 （Q8RQE9） BACTERIAL RNA POLYMERASE BETA-PRIME SUBUNIT; CHAIN D, N × 1 （Q8RQE8） BACTERIAL RNA POLYMERASE OMEGA SUBUNIT; CHAIN E, O × 1 （Q8RQE7） PHOSPHATE ION × 2 MAGNESIUM ION × 2 (4S)-2-METHYL-2,4-PENTANEDIOL × 2 ZINC ION × 2 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate × 1 water × 5 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 DNA-directed RNA polymerase subunit alpha; CHAIN A, B, K, L × 2 （Q5SHR6） BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M × 1 （Q8RQE9） BACTERIAL RNA POLYMERASE BETA-PRIME SUBUNIT; CHAIN D, N × 1 （Q8RQE8） BACTERIAL RNA POLYMERASE OMEGA SUBUNIT; CHAIN E, O × 1 （Q8RQE7） MAGNESIUM ION × 1 (4S)-2-METHYL-2,4-PENTANEDIOL × 1 ZINC ION × 2 methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1zyr 1zyr 2a6e 2a6e 2a6h 2a6h 2be5 2be5 2cw0 2cw0 3dxj 3dxj

74 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name Q5SKW1_THET8
Isoform —
PDB entities 5
Chains and sequence ranges Author chain F； PDBConstruct 1–423； UniProt 1–423 Author chain P； PDBConstruct 1–423； UniProt 1–423

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3dxj
Deposition date deposition_date2008-07-24
Structure title titleCrystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin
Keywords keywords;RNA POLYMERASE; RNAP; DRUG COMPLEX; INHIBITOR; corallopyronin; ripostatin; TRANSCRIPTION; HOLOENZYME; CRYSTALLOGRAPHY; TWINNING; HEMIHEDRAL, DNA-directed RNA polymerase, Nucleotidyltransferase, Transcription, Transferase, DNA-binding, Sigma factor, Transcription regulation ;; TRANSCRIPTION,TRANSFERASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3dxj__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3dxj__assembly_2__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3dxj__assembly_2__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）53.77 Å
Rg (electron density)54.42 Å
Total Rg54.40 Å
Atom count28050
Residues3541
Excluded volume501520 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3dxj__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 3dxj__assembly_2__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (11)

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6. Fold Classification (SCOP + CATH) 48 domains

SCOP 2.08 (12 domains)

Domain ID domain_idd3dxjc_
Class classe — Multi-domain proteins (alpha and beta)
Fold Fold folde.29 — beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily Superfamily superfamilye.29.1 — beta and beta-prime subunits of DNA dependent RNA-polymerase
Family Family familye.29.1.1 — RNA-polymerase beta
Domain ID domain_idd3dxjd_
Class classe — Multi-domain proteins (alpha and beta)
Fold Fold folde.29 — beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily Superfamily superfamilye.29.1 — beta and beta-prime subunits of DNA dependent RNA-polymerase
Family Family familye.29.1.2 — RNA-polymerase beta-prime
Domain ID domain_idd3dxje_
Class classa — All alpha proteins
Fold Fold folda.143 — RPB6/omega subunit-like
Superfamily Superfamily superfamilya.143.1 — RPB6/omega subunit-like
Family Family familya.143.1.1 — RNA polymerase omega subunit
Domain ID domain_idd3dxjf1
Class classa — All alpha proteins
Fold Fold folda.177 — Sigma2 domain of RNA polymerase sigma factors
Superfamily Superfamily superfamilya.177.1 — Sigma2 domain of RNA polymerase sigma factors
Family Family familya.177.1.1 — Sigma2 domain of RNA polymerase sigma factors
Domain ID domain_idd3dxjf2
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.13 — Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family Family familya.4.13.0 — automated matches
Domain ID domain_idd3dxjf3
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.13 — Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family Family familya.4.13.0 — automated matches
Domain ID domain_idd3dxjm_
Class classe — Multi-domain proteins (alpha and beta)
Fold Fold folde.29 — beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily Superfamily superfamilye.29.1 — beta and beta-prime subunits of DNA dependent RNA-polymerase
Family Family familye.29.1.1 — RNA-polymerase beta
Domain ID domain_idd3dxjn_
Class classe — Multi-domain proteins (alpha and beta)
Fold Fold folde.29 — beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily Superfamily superfamilye.29.1 — beta and beta-prime subunits of DNA dependent RNA-polymerase
Family Family familye.29.1.2 — RNA-polymerase beta-prime
Domain ID domain_idd3dxjo_
Class classa — All alpha proteins
Fold Fold folda.143 — RPB6/omega subunit-like
Superfamily Superfamily superfamilya.143.1 — RPB6/omega subunit-like
Family Family familya.143.1.1 — RNA polymerase omega subunit
Domain ID domain_idd3dxjp1
Class classa — All alpha proteins
Fold Fold folda.177 — Sigma2 domain of RNA polymerase sigma factors
Superfamily Superfamily superfamilya.177.1 — Sigma2 domain of RNA polymerase sigma factors
Family Family familya.177.1.1 — Sigma2 domain of RNA polymerase sigma factors
Domain ID domain_idd3dxjp2
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.13 — Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family Family familya.4.13.0 — automated matches
Domain ID domain_idd3dxjp3
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.13 — Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family Family familya.4.13.0 — automated matches

CATH v4.4 (36 domains)

Domain ID domain_id3dxjA01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily10 — RNA polymerase, RBP11-like subunit
Domain ID domain_id3dxjA02
Class class2 — Mainly Beta
Architecture architecture170 — Beta Complex
Topology topology120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
Homologous superfamily homologous superfamily12 — DNA-directed RNA polymerase, insert domain
Domain ID domain_id3dxjB01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily10 — RNA polymerase, RBP11-like subunit
Domain ID domain_id3dxjB02
Class class2 — Mainly Beta
Architecture architecture170 — Beta Complex
Topology topology120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
Homologous superfamily homologous superfamily12 — DNA-directed RNA polymerase, insert domain
Domain ID domain_id3dxjC01
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology270 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6
Homologous superfamily homologous superfamily10 — DNA-directed RNA polymerase, subunit 2, domain 6
Domain ID domain_id3dxjC02
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology1100 — Rna Polymerase Beta Subunit; Chain: C,domain 2
Homologous superfamily homologous superfamily10 —
Domain ID domain_id3dxjC03
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology1110 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3
Homologous superfamily homologous superfamily10 — RNA polymerase Rpb2, domain 2
Domain ID domain_id3dxjC04
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology150 — Rna Polymerase Beta Subunit; Chain: C, domain 4
Homologous superfamily homologous superfamily10 — DNA-directed RNA polymerase, beta subunit, external 1 domain
Domain ID domain_id3dxjC05
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
Domain ID domain_id3dxjC06
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily150 — RNA polymerase II, Rpb2 subunit, wall domain
Domain ID domain_id3dxjD04
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
Domain ID domain_id3dxjD05
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology40 — Barwin-like endoglucanases
Homologous superfamily homologous superfamily20 —
Domain ID domain_id3dxjD06
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology274 — Enzyme I; Chain A, domain 2
Homologous superfamily homologous superfamily100 — RNA polymerase Rpb1, domain 3
Domain ID domain_id3dxjD07
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology132 — Topoisomerase I; Chain A, domain 4
Homologous superfamily homologous superfamily30 — RNA polymerase Rpb1 funnel domain
Domain ID domain_id3dxjE00
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology940 — Eukaryotic RPB6 RNA polymerase subunit
Homologous superfamily homologous superfamily10 — RNA polymerase subunit, RPB6/omega
Domain ID domain_id3dxjF01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1810 —
Domain ID domain_id3dxjF02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Domain ID domain_id3dxjF03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Domain ID domain_id3dxjK01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily10 — RNA polymerase, RBP11-like subunit
Domain ID domain_id3dxjK02
Class class2 — Mainly Beta
Architecture architecture170 — Beta Complex
Topology topology120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
Homologous superfamily homologous superfamily12 — DNA-directed RNA polymerase, insert domain
Domain ID domain_id3dxjL01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily10 — RNA polymerase, RBP11-like subunit
Domain ID domain_id3dxjL02
Class class2 — Mainly Beta
Architecture architecture170 — Beta Complex
Topology topology120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
Homologous superfamily homologous superfamily12 — DNA-directed RNA polymerase, insert domain
Domain ID domain_id3dxjM01
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology270 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6
Homologous superfamily homologous superfamily10 — DNA-directed RNA polymerase, subunit 2, domain 6
Domain ID domain_id3dxjM02
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology1100 — Rna Polymerase Beta Subunit; Chain: C,domain 2
Homologous superfamily homologous superfamily10 —
Domain ID domain_id3dxjM03
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology1110 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3
Homologous superfamily homologous superfamily10 — RNA polymerase Rpb2, domain 2
Domain ID domain_id3dxjM04
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology150 — Rna Polymerase Beta Subunit; Chain: C, domain 4
Homologous superfamily homologous superfamily10 — DNA-directed RNA polymerase, beta subunit, external 1 domain
Domain ID domain_id3dxjM05
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
Domain ID domain_id3dxjM06
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily150 — RNA polymerase II, Rpb2 subunit, wall domain
Domain ID domain_id3dxjN04
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
Domain ID domain_id3dxjN05
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology40 — Barwin-like endoglucanases
Homologous superfamily homologous superfamily20 —
Domain ID domain_id3dxjN06
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology274 — Enzyme I; Chain A, domain 2
Homologous superfamily homologous superfamily100 — RNA polymerase Rpb1, domain 3
Domain ID domain_id3dxjN07
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology132 — Topoisomerase I; Chain A, domain 4
Homologous superfamily homologous superfamily30 — RNA polymerase Rpb1 funnel domain
Domain ID domain_id3dxjO00
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology940 — Eukaryotic RPB6 RNA polymerase subunit
Homologous superfamily homologous superfamily10 — RNA polymerase subunit, RPB6/omega
Domain ID domain_id3dxjP01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1810 —
Domain ID domain_id3dxjP02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Domain ID domain_id3dxjP03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
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7. Citations (1)