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3eqt

Crystal structure of human LGP2 C-terminal domain in complex with dsRNA

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

ATP-dependent RNA helicase DHX58

Homo sapiens

UniProt Q96C10

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Homooligomer Protein 2 RNA 2 5'-R(*GP*CP*GP*CP*GP*CP*GP*C)-3' × 2 ZINC ION × 2 water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
2rqa 2w4r 2w4r 2w4r 2w4r

5 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3eqt 9lou 9lov

3 assemblies

View Construct and Data Evidence
UniProt name DHX58_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–138； UniProt 541–678 Author chain B； PDBConstruct 1–138； UniProt 541–678

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3eqt
Deposition date deposition_date2008-10-01
Structure title titleCrystal structure of human LGP2 C-terminal domain in complex with dsRNA
Keywords keywords;innate immunity, RIG-I-like helicases, viral RNA detection, LGP2-dsRNA complex, ATP-binding, Coiled coil, Cytoplasm, Helicase, Hydrolase, Immune response, Nucleotide-binding, Polymorphism, RNA-binding, RNA BINDING PROTEIN-RNA COMPLEX ;; RNA BINDING PROTEIN/RNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3eqt__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3eqt__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3eqt__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）22.18 Å
Rg (electron density)21.86 Å
Total Rg22.34 Å
Atom count2506
Residues285
Excluded volume43439 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3eqt__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 2 domains

CATH v4.4 (2 domains)

Domain ID domain_id3eqtA00
Class class2 — Mainly Beta
Architecture architecture170 — Beta Complex
Topology topology150 — Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A
Homologous superfamily homologous superfamily30 — RIG-I-like receptor, C-terminal regulatory domain
Domain ID domain_id3eqtB00
Class class2 — Mainly Beta
Architecture architecture170 — Beta Complex
Topology topology150 — Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A
Homologous superfamily homologous superfamily30 — RIG-I-like receptor, C-terminal regulatory domain
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7. Citations (1)