3fhn

Structure of Tip20p

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Protein transport protein TIP20

Saccharomyces cerevisiae

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein monomer	Monomer	Protein 1	No other associated polymer	Consistent with protein count
2	Protein monomer	Monomer	Protein 1	No other associated polymer	Consistent with protein count
3	Protein monomer	Monomer	Protein 1	No other associated polymer	Consistent with protein count
4	Protein monomer	Monomer	Protein 1	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TIP20_YEAST
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 7–706； UniProt 2–701 Author chain B； PDBConstruct 7–706； UniProt 2–701 Author chain C； PDBConstruct 7–706； UniProt 2–701 Author chain D； PDBConstruct 7–706； UniProt 2–701

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	3fhn
Deposition date deposition_date	2008-12-09
Structure title title	Structure of Tip20p
Keywords keywords	;Tip20p, vesicle tethering, Endoplasmic reticulum, ER-Golgi transport, Membrane, Phosphoprotein, Protein transport, Transport, TRANSPORT PROTEIN ;; TRANSPORT PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3fhn__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3fhn__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

3fhn__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	44.74 Å
Rg (electron density)	45.07 Å
Total Rg	44.87 Å
Atom count	5510
Residues	663
Excluded volume	99041 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`3fhn__assembly_1__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`3fhn__assembly_2__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`3fhn__assembly_3__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`3fhn__assembly_4__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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6. Fold Classification (SCOP + CATH) 20 domains

CATH v4.4 (20 domains)

Domain ID domain_id	3fhnA01
Class class	6 — Special
Architecture architecture	10 — Helix non-globular
Topology topology	280 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	210 — Dsl1p vesicle tethering complex, Tip20p subunit, domain A

Domain ID domain_id	3fhnA02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	1420 — Dsl1p vesicle tethering complex, Tip20p subunit, domain B

Domain ID domain_id	3fhnA03
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	357 — Tetracycline Repressor; domain 2
Homologous superfamily homologous superfamily	100 — Dsl1p vesicle tethering complex, Tip20p subunit, domain C

Domain ID domain_id	3fhnA04
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	670 — Dsl1p vesicle tethering complex, Tip20p subunit, domain D

Domain ID domain_id	3fhnA05
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily	2270 — Dsl1p vesicle tethering complex, Tip20p subunit, domain E

Domain ID domain_id	3fhnB01
Class class	6 — Special
Architecture architecture	10 — Helix non-globular
Topology topology	280 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	210 — Dsl1p vesicle tethering complex, Tip20p subunit, domain A

Domain ID domain_id	3fhnB02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	1420 — Dsl1p vesicle tethering complex, Tip20p subunit, domain B

Domain ID domain_id	3fhnB03
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	357 — Tetracycline Repressor; domain 2
Homologous superfamily homologous superfamily	100 — Dsl1p vesicle tethering complex, Tip20p subunit, domain C

Domain ID domain_id	3fhnB04
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	670 — Dsl1p vesicle tethering complex, Tip20p subunit, domain D

Domain ID domain_id	3fhnB05
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily	2270 — Dsl1p vesicle tethering complex, Tip20p subunit, domain E

Domain ID domain_id	3fhnC01
Class class	6 — Special
Architecture architecture	10 — Helix non-globular
Topology topology	280 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	210 — Dsl1p vesicle tethering complex, Tip20p subunit, domain A

Domain ID domain_id	3fhnC02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	1420 — Dsl1p vesicle tethering complex, Tip20p subunit, domain B

Domain ID domain_id	3fhnC03
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	357 — Tetracycline Repressor; domain 2
Homologous superfamily homologous superfamily	100 — Dsl1p vesicle tethering complex, Tip20p subunit, domain C

Domain ID domain_id	3fhnC04
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	670 — Dsl1p vesicle tethering complex, Tip20p subunit, domain D

Domain ID domain_id	3fhnC05
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily	2270 — Dsl1p vesicle tethering complex, Tip20p subunit, domain E

Domain ID domain_id	3fhnD01
Class class	6 — Special
Architecture architecture	10 — Helix non-globular
Topology topology	280 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	210 — Dsl1p vesicle tethering complex, Tip20p subunit, domain A

Domain ID domain_id	3fhnD02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	1420 — Dsl1p vesicle tethering complex, Tip20p subunit, domain B

Domain ID domain_id	3fhnD03
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	357 — Tetracycline Repressor; domain 2
Homologous superfamily homologous superfamily	100 — Dsl1p vesicle tethering complex, Tip20p subunit, domain C

Domain ID domain_id	3fhnD04
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	670 — Dsl1p vesicle tethering complex, Tip20p subunit, domain D

Domain ID domain_id	3fhnD05
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily	2270 — Dsl1p vesicle tethering complex, Tip20p subunit, domain E

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Unit-cell length a length_a	85.480 Å
Unit-cell length b length_b	111.620 Å
Unit-cell length c length_c	149.840 Å
Unit-cell angle α angle_alpha	77.09 °
Unit-cell angle β angle_beta	88.12 °
Unit-cell angle γ angle_gamma	70.35 °
Molecules per unit cell Z z_pdb	4

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	3.000 Å
Low-resolution limit resolution_low	29.900 Å
R factor r_factor	0.2200
R_work r_work	0.2200
R_free r_free	0.2650

Description description	Protein transport protein TIP20
Molecular weight formula_weight	82219.3 kDa
Source method src_method	man
Copy count entity_count	4

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D
Atom count atom_count	22040

Structure of Tip20p

1. Protein Identity and Related Structures Protein Identity & Related Structures

Protein transport protein TIP20

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

3fhn__assembly_1__model_1

3fhn__assembly_1__model_1 | I(q)

3fhn__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 20 domains

CATH v4.4 (20 domains)

7. Citations (1)

Source organism organism	Saccharomyces cerevisiae
Common name common_name	yeast
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Escherichia coli

Structure of Tip20p

1. Protein Identity and Related Structures Protein Identity & Related Structures

Protein transport protein TIP20

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

3fhn__assembly_1__model_1

3fhn__assembly_1__model_1 | I(q)

3fhn__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 20 domains

CATH v4.4 (20 domains)

7. Citations (1)