Escherichia coli K-12
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | Nanobody × 1 water × 2 | Consistent with protein count |
| UniProt name | DYR_ECOLI |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–159； UniProt 1–159 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 3k74 |
| Deposition date deposition_date | 2009-10-12 |
| Structure title title | Disruption of protein dynamics by an allosteric effector antibody |
| Keywords keywords | ;Immunoglobulin, protein-nanobody complex, Antibiotic resistance, Methotrexate resistance, NADP, One-carbon metabolism, Oxidoreductase, Trimethoprim resistance ;; OXIDOREDUCTASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 21.65 Å |
| Rg (electron density) | 20.74 Å |
| Total Rg | 21.62 Å |
| Atom count | 2149 |
| Residues | 274 |
| Excluded volume | 38034 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d3k74a_ |
| Class class | c — Alpha and beta proteins (a/b) |
| Fold Fold fold | c.71 — Dihydrofolate reductase-like |
| Superfamily Superfamily superfamily | c.71.1 — Dihydrofolate reductase-like |
| Family Family family | c.71.1.1 — Dihydrofolate reductases |
| Domain ID domain_id | d3k74b_ |
| Class class | b — All beta proteins |
| Fold Fold fold | b.1 — Immunoglobulin-like beta-sandwich |
| Superfamily Superfamily superfamily | b.1.1 — Immunoglobulin |
| Family Family family | b.1.1.1 — V set domains (antibody variable domain-like) |
| Domain ID domain_id | 3k74A00 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| Topology topology | 430 — Dihydrofolate Reductase, subunit A |
| Homologous superfamily homologous superfamily | 10 — Dihydrofolate Reductase, subunit A |
| Domain ID domain_id | 3k74B00 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 40 — Immunoglobulin-like |
| Homologous superfamily homologous superfamily | 10 — Immunoglobulins |