3ow2

Crystal Structure of Enhanced Macrolide Bound to 50S Ribosomal Subunit

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

50S ribosomal protein L2P

OrganismNot specified

UniProt P20276

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL2_HALMA
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain A； PDBConstruct 1–237； UniProt 1–237

50S ribosomal protein L3P

OrganismNot specified

UniProt P20279

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL3_HALMA
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain B； PDBConstruct 1–337； UniProt 2–338

50S ribosomal protein L4P

OrganismNot specified

UniProt P12735

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL4_HALMA
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain C； PDBConstruct 1–246； UniProt 1–246

50S ribosomal protein L5P

OrganismNot specified

UniProt P14124

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL5_HALMA
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain D； PDBConstruct 1–165； UniProt 10–174

50S ribosomal protein L6P

OrganismNot specified

UniProt P14135

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL6_HALMA
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain E； PDBConstruct 1–172； UniProt 2–173

50S ribosomal protein L7Ae

OrganismNot specified

UniProt P12743

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL7A_HALMA
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain F； PDBConstruct 1–119； UniProt 2–120

50S ribosomal protein L10E

OrganismNot specified

UniProt P15825

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RLA0_HALMA
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain G； PDBConstruct 1–62； UniProt 12–73

50S ribosomal protein L13P

OrganismNot specified

UniProt P29198

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL13_HALMA
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain I； PDBConstruct 1–142； UniProt 4–145

50S ribosomal protein L14P

OrganismNot specified

UniProt P22450

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL14_HALMA
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain J； PDBConstruct 1–132； UniProt 1–132

50S ribosomal protein L15P

OrganismNot specified

UniProt P12737

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL15_HALMA
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain K； PDBConstruct 1–150； UniProt 1–150

50S ribosomal protein L18P

OrganismNot specified

UniProt P14123

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL18_HALMA
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain M； PDBConstruct 1–186； UniProt 1–186

50S ribosomal protein L18e

OrganismNot specified

UniProt P12733

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL18E_HALMA
Isoform	—
PDB entities	16
Chains and sequence ranges	Author chain N； PDBConstruct 1–115； UniProt 1–115

50S ribosomal protein L19e

OrganismNot specified

UniProt P14119

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL19_HALMA
Isoform	—
PDB entities	17
Chains and sequence ranges	Author chain O； PDBConstruct 1–143； UniProt 1–143

50S ribosomal protein L21e

OrganismNot specified

UniProt P12734

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL21_HALMA
Isoform	—
PDB entities	18
Chains and sequence ranges	Author chain P； PDBConstruct 1–95； UniProt 1–95

50S ribosomal protein L22P

OrganismNot specified

UniProt P10970

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL22_HALMA
Isoform	—
PDB entities	19
Chains and sequence ranges	Author chain Q； PDBConstruct 1–150； UniProt 1–150

50S ribosomal protein L23P

OrganismNot specified

UniProt P12732

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL23_HALMA
Isoform	—
PDB entities	20
Chains and sequence ranges	Author chain R； PDBConstruct 1–81； UniProt 1–81

50S ribosomal protein L24P

OrganismNot specified

UniProt P10972

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL24_HALMA
Isoform	—
PDB entities	21
Chains and sequence ranges	Author chain S； PDBConstruct 1–119； UniProt 1–119

50S ribosomal protein L24e

OrganismNot specified

UniProt P14116

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL24E_HALMA
Isoform	—
PDB entities	22
Chains and sequence ranges	Author chain T； PDBConstruct 1–53； UniProt 4–56

50S ribosomal protein L29P

OrganismNot specified

UniProt P10971

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL29_HALMA
Isoform	—
PDB entities	23
Chains and sequence ranges	Author chain U； PDBConstruct 1–65； UniProt 1–65

50S ribosomal protein L30P

OrganismNot specified

UniProt P14121

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL30_HALMA
Isoform	—
PDB entities	24
Chains and sequence ranges	Author chain V； PDBConstruct 1–154； UniProt 1–154

50S ribosomal protein L31e

OrganismNot specified

UniProt P18138

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL31_HALMA
Isoform	—
PDB entities	25
Chains and sequence ranges	Author chain W； PDBConstruct 1–82； UniProt 7–88

50S ribosomal protein L32e

OrganismNot specified

UniProt P12736

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL32_HALMA
Isoform	—
PDB entities	26
Chains and sequence ranges	Author chain X； PDBConstruct 1–142； UniProt 96–237

50S ribosomal protein L37e

OrganismNot specified

UniProt P32410

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L39e × 1 （P22452） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL37_HALMA
Isoform	—
PDB entities	28
Chains and sequence ranges	Author chain Z； PDBConstruct 1–56； UniProt 1–56

50S ribosomal protein L39e

OrganismNot specified

UniProt P22452

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L44E × 1 （P32411） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL39_HALMA
Isoform	—
PDB entities	29
Chains and sequence ranges	Author chain 1； PDBConstruct 1–48； UniProt 1–48

50S ribosomal protein L44E

OrganismNot specified

UniProt P32411

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	23S RIBOSOMAL RNA × 1 5S RIBOSOMAL RNA × 1 50S ribosomal protein L2P × 1 （P20276） 50S ribosomal protein L3P × 1 （P20279） 50S ribosomal protein L4P × 1 （P12735） 50S ribosomal protein L5P × 1 （P14124） 50S ribosomal protein L6P × 1 （P14135） 50S ribosomal protein L7Ae × 1 （P12743） 50S ribosomal protein L10E × 1 （P15825） 50S ribosomal protein L10e × 1 50S ribosomal protein L13P × 1 （P29198） 50S ribosomal protein L14P × 1 （P22450） 50S ribosomal protein L15P × 1 （P12737） 50S ribosomal protein L15e × 1 50S ribosomal protein L18P × 1 （P14123） 50S ribosomal protein L18e × 1 （P12733） 50S ribosomal protein L19e × 1 （P14119） 50S ribosomal protein L21e × 1 （P12734） 50S ribosomal protein L22P × 1 （P10970） 50S ribosomal protein L23P × 1 （P12732） 50S ribosomal protein L24P × 1 （P10972） 50S ribosomal protein L24e × 1 （P14116） 50S ribosomal protein L29P × 1 （P10971） 50S ribosomal protein L30P × 1 （P14121） 50S ribosomal protein L31e × 1 （P18138） 50S ribosomal protein L32e × 1 （P12736） 50S ribosomal protein L37Ae × 1 50S ribosomal protein L37e × 1 （P32410） 50S ribosomal protein L39e × 1 （P22452） MAGNESIUM ION × 61 POTASSIUM ION × 1 SODIUM ION × 26 CHLORIDE ION × 13 STRONTIUM ION × 98 ;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ; × 1 CADMIUM ION × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL44_HALMA
Isoform	—
PDB entities	30
Chains and sequence ranges	Author chain 2； PDBConstruct 1–92； UniProt 1–92

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	3ow2
Deposition date deposition_date	2010-09-17
Structure title title	Crystal Structure of Enhanced Macrolide Bound to 50S Ribosomal Subunit
Keywords keywords	Ribosome, Protein Translation, Macrolide binding; RIBOSOME
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3ow2__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3ow2__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

3ow2__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	68.32 Å
Rg (electron density)	69.11 Å
Total Rg	68.95 Å
Atom count	90725
Residues	6577
Excluded volume	1384200 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`3ow2__assembly_1__model_1`	30-meric （30）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (37)

Entity 1 Entity 1 polymer

Description description	23S RIBOSOMAL RNA
Molecular weight formula_weight	939691.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	0
Atom count atom_count	90725

UAUGCCAGCUGGUGGAUUGCUCGGCUCAGGCGCUGAUGAAGGACGUGCCAAGCUGCGAUAAGCCAUGGGGAGCCGCACGGAGGCGAAGAACCAUGGAUUUCCGAAUGAGAAUCUCUAACAAUUGCUUCGCGCAAUGAGGAACCCCGAGAACUGAAACAUCUCAGUAUCGGGAGGAACAGAAAACGCAAUGUGAUGUCGUUAGUAACCGCGAGUGAACGCGAUACAGCCCAAACCGAAGCCCUCACGGGCAAUGUGGUGUCAGGGCUACCUCUCAUCAGCCGACCGUCUCGACGAAGUCUCUUGGAACAGAGCGUGAUACAGGGUGACAACCCCGUACUCGAGACCAGUACGACGUGCGGUAGUGCCAGAGUAGCGGGGGUUGGAUAUCCCUCGCGAAUAACGCAGGCAUCGACUGCGAAGGCUAAACACAACCUGAGACCGAUAGUGAACAAGUAGUGUGAACGAACGCUGCAAAGUACCCUCAGAAGGGAGGCGAAAUAGAGCAUGAAAUCAGUUGGCGAUCGAGCGACAGGGCAUACAAGGUCCCUCGACGAAUGACCGACGCGCGAGCGUCCAGUAAGACUCACGGGAAGCCGAUGUUCUGUCGUACGUUUUGAAAAACGAGCCAGGGAGUGUGUCUGCAUGGCAAGUCUAACCGGAGUAUCCGGGGAGGCACAGGGAAACCGACAUGGCCGCAGGGCUUGCCCGAGGGCCGCCGUCUUCAAGGGCGGGGAGCCAUGUGGACACGACCCGAAUCCGGACGAUCUACGCAUGGACAAGAUGAAGCGUGCCGAAAGGCACGUGGAAGUCUGUUAGAGUUGGUGUCCUACAAUACCCUCUCGUGAUCUAUGUGUAGGGGUGAAAGGCCCAUCGAGUCCGGCAACAGCUGGUUCCAAUCGAAACAUGUCGAAGCAUGACCUCCGCCGAGGUAGUCUGUGAGGUAGAGCGACCGAUUGGUGUGUCCGCCUCCGAGAGGAGUCGGCACACCUGUCAAACUCCAAACUUACAGACGCCGUUUGACGCGGGGAUUCCGGUGCGCGGGGUAAGCCUGUGUACCAGGAGGGGAACAACCCAGAGAUAGGUUAAGGUCCCCAAGUGUGGAUUAAGUGUAAUCCUCUGAAGGUGGUCUCGAGCCCUAGACAGCCGGGAGGUGAGCUUAGAAGCAGCUACCCUCUAAGAAAAGCGUAACAGCUUACCGGCCGAGGUUUGAGGCGCCCAAAAUGAUCGGGACUCAAAUCCACCACCGAGACCUGUCCGUACCACUCAUACUGGUAAUCGAGUAGAUUGGCGCUCUAAUUGGAUGGAAGUAGGGGUGAAAACUCCUAUGGACCGAUUAGUGACGAAAAUCCUGGCCAUAGUAGCAGCGAUAGUCGGGUGAGAACCCCGACGGCCUAAUGGAUAAGGGUUCCUCAGCACUGCUGAUCAGCUGAGGGUUAGCCGGUCCUAAGUCAUACCGCAACUCGACUAUGACGAAAUGGGAAACGGGUUAAUAUUCCCGUGCCACUAUGCAGUGAAAGUUGACGCCCUGGGGUCGAUCACGCUGGGCAUUCGCCCAGUCGAACCGUCCAACUCCGUGGAAGCCGUAAUGGCAGGAAGCGGACGAACGGCGGCAUAGGGAAACGUGAUUCAACCUGGGGCCCAUGAAAAGACGAGCAUAGUGUCCGUACCGAGAACCGACACAGGUGUCCAUGGCGGCGAAAGCCAAGGCCUGUCGGGAGCAACCAACGUUAGGGAAUUCGGCAAGUUAGUCCCGUACCUUCGGAAGAAGGGAUGCCUGCUCCGGAACGGAGCAGGUCGCAGUGACUCGGAAGCUCGGACUGUCUAGUAACAACAUAGGUGACCGCAAAUCCGCAAGGACUCGUACGGUCACUGAAUCCUGCCCAGUGCAGGUAUCUGAACACCUCGUACAAGAGGACGAAGGACCUGUCAACGGCGGGGGUAACUAUGACCCUCUUAAGGUAGCGUAGUACCUUGCCGCAUCAGUAGCGGCUUGCAUGAAUGGAUUAACCAGAGCUUCACUGUCCCAACGUUGGGCCCGGUGAACUGUACAUUCCAGUGCGGAGUCUGGAGACACCCAGGGGGAAGCAAAGACCCUAUGGAGCUUUACUGCAGGCUGUCGCUGAGACGUGGUCGCCGAUGUGCAGCAUAGGUAGGAGACACUACACAGGUACCCGCGCUAGCGGGCCACCGAGUCAACAGUGAAAUACUACCCGUCGGUGACUGCGACUCUCACUCCGGGAGGAGGACACCGAUAGCCGGGCAGUUUGACUGGGGCGGUACGCGCUCGAAAAGAUAUCGAGCGCGCCCUAUGGCUAUCUCAGCCGGGACAGAGACCCGGCGAAGAGUGCAAGAGCAAAAGAUAGCUUGACAGUGUUCUUCCCAACGAGGAACGCUGACGCGAAAGCGUGGUCUAGCGAACCAAUUAGCCUGCUUGAUGCGGGCAAUUGAUGACAGAAAAGCUACCCUAGGGAUAACAGAGUCGUCACUCGCAAGAGCACAUAUCGACCGAGUGGCUUGCUACCUCGAUGUCGGUUCCCUCCAUCCUGCCCGUGCAGAAGCGGGCAAGGGUGAGGUUGUUCGCCUAUUAAAGGAGGUCGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUCGGCUGCUAUCUACUGGGUGUGUAAUGGUGUCUGACAAGAACGACCGUAUAGUACGAGAGGAACUACGGUUGGUGGCCACUGGUGUACCGGUUGUUCGAGAGAGCACGUGCCGGGUAGCCACGCCACACGGGGUAAGAGCUGAACGCAUCUAAGCUCGAAACCCACUUGGAAAAGAGACACCGCCGAGGUCCCGCGUACAAGACGCGGUCGAUAGACUCGGGGUGUGCGCGUCGAGGUAACGAGACGUUAAGCCCACGAGCACUAACAGACCAA

Entity 2 Entity 2 polymer

Description description	5S RIBOSOMAL RNA
Molecular weight formula_weight	39318.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	9

UUAGGCGGCCACAGCGGUGGGGUUGCCUCCCGUACCCAUCCCGAACACGGAAGAUAAGCCCACCAGCGUUCCGGGGAGUACUGGAGUGCGCGAGCCUCUGGGAAACCCGGUUCGCCGCCACC

Entity 3 Entity 3 polymer

Description description	50S ribosomal protein L2P
Molecular weight formula_weight	24994.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A

GRRIQGQRRGRGTSTFRAPSHRYKADLEHRKVEDGDVIAGTVVDIEHDPARSAPVAAVEFEDGDRRLILAPEGVGVGDELQVGVDAEIAPGNTLPLAEIPEGVPVCNVESSPGDGGKFARASGVNAQLLTHDRNVAVVKLPSGEMKRLDPQCRATIGVVGGGGRTDKPFVKAGNKHHKMKARGTKWPNVRGVAMNAVDHPFGGGGRQHPGKPKSISRNAPPGRKVGDIASKRTGRGG

Entity 4 Entity 4 polymer

Description description	50S ribosomal protein L3P
Molecular weight formula_weight	37265.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

PQPSRPRKGSLGFGPRKRSTSETPRFNSWPSDDGQPGVQGFAGYKAGMTHVVLVNDEPNSPREGMEETVPVTVIETPPMRAVALRAYEDTPYGQRPLTEVWTDEFHSELDRTLDVPEDHDPDAAEEQIRDAHEAGDLGDLRLITHTVPDAVPSVPKKKPDVMETRVGGGSVSDRLDHALDIVEDGGEHAMNDIFRAGEYADVAGVTKGKGTQGPVKRWGVQKRKGKHARQGWRRRIGNLGPWNPSRVRSTVPQQGQTGYHQRTELNKRLIDIGEGDEPTVDGGFVNYGEVDGPYTLVKGSVPGPDKRLVRFRPAVRPNDQPRLDPEVRYVSNESNQG

Entity 5 Entity 5 polymer

Description description	50S ribosomal protein L4P
Molecular weight formula_weight	26442.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKLDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER

Entity 6 Entity 6 polymer

Description description	50S ribosomal protein L5P
Molecular weight formula_weight	18368.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D

FHEMREPRIEKVVVHMGIGHGGRDLANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGVEEHTEFPSQEYDPSIGIYGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV

Entity 7 Entity 7 polymer

Description description	50S ribosomal protein L6P
Molecular weight formula_weight	19316.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP

Entity 8 Entity 8 polymer

Description description	50S ribosomal protein L7Ae
Molecular weight formula_weight	12600.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F

PVYVDFDVPADLEDDALEALEVARDTGAVKKGTNETTKSIERGSAELVFVAEDVQPEEIVMHIPELADEKGVPFIFVEQQDDLGHAAGLEVGSAAAAVTDAGAAATVLEEIADKVEELR

Entity 9 Entity 9 polymer

Description description	50S ribosomal protein L10E
Molecular weight formula_weight	7101.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G

IPEWKQEEVDAIVEMIESYESVGVVNIAGIPSRQLQDMRRDLHGTAELRVSRNTLLERALDD

Entity 10 Entity 10 polymer

Description description	50S ribosomal protein L10e
Molecular weight formula_weight	18022.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

KPGAMYRNSSKPAYTRREYISGIPGKKIAQFDMGNNGAGPTYPAQVELVVEKPVQIRHNALEAARVAANRYVQNSGAAANYKFRIRKFPFHVIRENKAAAAAAAAAAADGMRAPFGKPVGTAARVHGANHIFIAWVNPDPNVEEAWRRAKMKVTPTINIDSSPAGNA

Entity 11 Entity 11 polymer

Description description	50S ribosomal protein L13P
Molecular weight formula_weight	15931.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

AEFDADVIVDARDCIMGRVASQVAEQALDGETVAVVNAERAVITGREEQIVEKYEKRVDIGNDNGYFYPKRPDGIFKRTIRGMLPHKKQRGREAFESVRVYLGNPYDEDGEVLDGTSLDRLSNIKFVTLGEISETLGANKTW

Entity 12 Entity 12 polymer

Description description	50S ribosomal protein L14P
Molecular weight formula_weight	14216.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J

MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV

Entity 13 Entity 13 polymer

Description description	50S ribosomal protein L15P
Molecular weight formula_weight	16368.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K

TSKKKRQRGSRTHGGGSHKNRRGAGHRGGRGDAGRDKHEFHNHEPLGKSGFKRPQKVQEEAATIDVREIDENVTLLAADDVAEVEDGGFRVDVRDVVEEADDADYVKVLGAGQVRHELTLIADDFSEGAREKVEGAGGSVELTDLGEERQ

Entity 14 Entity 14 polymer

Description description	50S ribosomal protein L15e
Molecular weight formula_weight	22856.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L

ARSAYSYIREAWKRPKEGQIAELMWHRMQEWRNEPAVVRIERPTRLDRARSLGYKAKQGIIVVRVAIRKGSSRRTRFNKGRRSKRMMVNRITRKKNIQRIAEERANRKFPNLRVLNSYSVGEDGRHKWHEVILIDPDHPAIKSDDQLSWISRTRHRLRTFRGLTSAGRRCRGLRGQGKGSEKVRPSLRVNGAKA

Entity 15 Entity 15 polymer

Description description	50S ribosomal protein L18P
Molecular weight formula_weight	20509.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	M

ATGPRYKVPMRRRREARTDYHQRLRLLKSGKPRLVARKSNKHVRAQLVTLGPNGDDTLASAHSSDLAEYGWEAPTGNMPSAYLTGLLAGLRAQEAGVEEAVLDIGLNSPTPGSKVFAIQEGAIDAGLDIPHNDDVLADWQRTRGAHIAEYDEQLEEPLYSGDFDAADLPEHFDELRETLLDGDIEL

Entity 16 Entity 16 polymer

Description description	50S ribosomal protein L18e
Molecular weight formula_weight	12307.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N

SKTNPRLSSLIADLKSAARSSGGAVWGDVAERLEKPRRTHAEVNLGRIERYAQEDETVVVPGKVLGSGVLQKDVTVAAVDFSGTAETKIDQVGEAVSLEQAIENNPEGSHVRVIR

Entity 17 Entity 17 polymer

Description description	50S ribosomal protein L19e
Molecular weight formula_weight	16135.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	O

TDLSAQKRLAADVLDVGKNRVWFNPERQGDIADAITREDVRELVDEGAIQAKDKKGNSRGRARERQKKRAKGHQKGAGSRKGKAGARQNSKEDWESRIRAQRTKLRELRDEGTLSSSQYRDLYDKAGGGEFDSVADLERYIDA

Entity 18 Entity 18 polymer

Description description	50S ribosomal protein L21e
Molecular weight formula_weight	10436.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	P

PSSNGPLEGTRGKLKNKPRDRGTSPPQRAVEEFDDGEKVHLKIDPSVPNGRFHPRFDGQTGTVEGKQGDAYKVDIVDGGKEKTIIVTAAHLRRQE

Entity 19 Entity 19 polymer

Description description	50S ribosomal protein L22P
Molecular weight formula_weight	16363.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Q

GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP

Entity 20 Entity 20 polymer

Description description	50S ribosomal protein L23P
Molecular weight formula_weight	9178.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	R

SWDVIKHPHVTEKAMNDMDFQNKLQFAVDDRASKGEVADAVEEQYDVTVEQVNTQNTMDGEKKAVVRLSEDDDAQEVASRI

Entity 21 Entity 21 polymer

Description description	50S ribosomal protein L24P
Molecular weight formula_weight	13539.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	S

SKQPDKQRKSQRRAPLHERHKQVRATLSADLREEYGQRNVRVNAGDTVEVLRGDFAGEEGEVINVDLDKAVIHVEDVTLEKTDGEEVPRPLDTSNVRVTDLDLEDEKREARLESEDDSA

Entity 22 Entity 22 polymer

Description description	50S ribosomal protein L24e
Molecular weight formula_weight	5919.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	T

RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR

Entity 23 Entity 23 polymer

Description description	50S ribosomal protein L29P
Molecular weight formula_weight	7145.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	U

TVLHVQEIRDMTPAEREAELDDLKTELLNARAVQAAGGAPENPGRIKELRKAIARIKTIQGEEGD

Entity 24 Entity 24 polymer

Description description	50S ribosomal protein L30P
Molecular weight formula_weight	17062.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	V

MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR

Entity 25 Entity 25 polymer

Description description	50S ribosomal protein L31e
Molecular weight formula_weight	9315.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	W

ERVVTIPLRDARAEPNHKRADKAMILIREHLAKHFSVDEDAVRLDPSINEAAWARGRANTPSKIRVRAARFEEEGEAIVEAE

Entity 26 Entity 26 polymer

Description description	50S ribosomal protein L32e
Molecular weight formula_weight	16079.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	X

TELQARGLTEKTPDLSDEDARLLTQRHRVGKPQFNRQDHHKKKRVSTSWRKPRGQLSKQRRGIKGKGDTVEAGFRSPTAVRGKHPSGFEEVRVHNVDDLEGVDGDTEAVRIASKVGARKRERIEEEAEDAGIRVLNPTYVEV

Entity 27 Entity 27 polymer

Description description	50S ribosomal protein L37Ae
Molecular weight formula_weight	8097.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Y

RTGRFGPRYGLKIRVRVADVEIKHKKKHKCPVCGFKKLKRAGTGIWMCGHCGYKIAGGCYQPETVAGKAVMKA

Entity 28 Entity 28 polymer

Description description	50S ribosomal protein L37e
Molecular weight formula_weight	6199.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Z

TGAGTPSQGKKNTTTHTKCRRCGEKSYHTKKKVCSSCGFGKSAKRRDYEWQSKAGE

Entity 29 Entity 29 polymer

Description description	50S ribosomal protein L39e
Molecular weight formula_weight	5844.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	1

GKKSKATKKRLAKLDNQNSRVPAWVMLKTDEVQRNHKRRHWRRNDTDE

Entity 30 Entity 30 polymer

Description description	50S ribosomal protein L44E
Molecular weight formula_weight	10815.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	2

MQMPRRFNTYCPHCNEHQEHEVEKVRSGRQTGMKWIDRQRERNSGIGNDGKFSKVPGGDKPTKKTDLKYRCGECGKAHLREGWRAGRLEFQE

Entity 31 Entity 31 non-polymer

Description description	MAGNESIUM ION
Molecular weight formula_weight	24.3 kDa
Source method src_method	syn
Copy count entity_count	61

Entity 32 Entity 32 non-polymer

Description description	POTASSIUM ION
Molecular weight formula_weight	39.1 kDa
Source method src_method	syn
Copy count entity_count	1

Entity 33 Entity 33 non-polymer

Description description	SODIUM ION
Molecular weight formula_weight	23.0 kDa
Source method src_method	syn
Copy count entity_count	26

Entity 34 Entity 34 non-polymer

Description description	CHLORIDE ION
Molecular weight formula_weight	35.5 kDa
Source method src_method	syn
Copy count entity_count	13

Entity 35 Entity 35 non-polymer

Description description	STRONTIUM ION
Molecular weight formula_weight	87.6 kDa
Source method src_method	syn
Copy count entity_count	98

Entity 36 Entity 36 non-polymer

Description description	;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside ;
Molecular weight formula_weight	1074.3 kDa
Source method src_method	syn
Copy count entity_count	1

Entity 37 Entity 37 non-polymer

Description description	CADMIUM ION
Molecular weight formula_weight	112.4 kDa
Source method src_method	syn
Copy count entity_count	4

▼

6. Fold Classification (SCOP + CATH) 34 domains

CATH v4.4 (34 domains)

Domain ID domain_id	3ow2100
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	1620 — Atp Synthase Epsilon Chain; Chain: I;
Homologous superfamily homologous superfamily	10 — Ribosomal protein L39

Domain ID domain_id	3ow2200
Class class	3 — Alpha Beta
Architecture architecture	10 — Roll
Topology topology	450 — Nuclear Transport Factor 2; Chain: A,
Homologous superfamily homologous superfamily	80 —

Domain ID domain_id	3ow2A01
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily	140 — Nucleic acid-binding proteins

Domain ID domain_id	3ow2A02
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	30 — SH3 type barrels.
Homologous superfamily homologous superfamily	30 —

Domain ID domain_id	3ow2B01
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	960 — Ribosomal protein L3; domain 3
Homologous superfamily homologous superfamily	10 — Ribosomal protein L3, domain 3

Domain ID domain_id	3ow2B02
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	30 — Elongation Factor Tu (Ef-tu); domain 3
Homologous superfamily homologous superfamily	10 — Translation factors

Domain ID domain_id	3ow2B03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1430 — Ribosomal Protein L3; Chain: B; domain 2,
Homologous superfamily homologous superfamily	10 —

Domain ID domain_id	3ow2C00
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	1370 — Ribosomal Protein L4; Chain: A;
Homologous superfamily homologous superfamily	10 — Ribosomal protein L4/L1

Domain ID domain_id	3ow2D00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1440 — 50s Ribosomal Protein L5; Chain: A,
Homologous superfamily homologous superfamily	10 — Ribosomal protein L5

Domain ID domain_id	3ow2E01
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	930 — Outer Surface Protein A; domain 3
Homologous superfamily homologous superfamily	12 — Ribosomal protein L6

Domain ID domain_id	3ow2E02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	930 — Outer Surface Protein A; domain 3
Homologous superfamily homologous superfamily	12 — Ribosomal protein L6

Domain ID domain_id	3ow2F00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1330 — 60s Ribosomal Protein L30; Chain: A;
Homologous superfamily homologous superfamily	30 — Ribosomal protein L30/S12

Domain ID domain_id	3ow2H00
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1170 — Aldehyde Oxidoreductase; domain 3
Homologous superfamily homologous superfamily	10 — Ribosomal protein L16/L10

Domain ID domain_id	3ow2I00
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1180 — Ribosomal Protein L13p; Chain: A;
Homologous superfamily homologous superfamily	10 — Ribosomal protein L13

Domain ID domain_id	3ow2J00
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	150 — Ribosomal Protein L14
Homologous superfamily homologous superfamily	20 — Ribosomal protein L14/L23

Domain ID domain_id	3ow2K01
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	990 — Molecule: Ribosomal Protein L15; Chain: K; domain 1
Homologous superfamily homologous superfamily	10 —

Domain ID domain_id	3ow2K02
Class class	3 — Alpha Beta
Architecture architecture	100 — Ribosomal Protein L15; Chain: K; domain 2
Topology topology	10 — Ribosomal Protein L15; Chain: K; domain 2
Homologous superfamily homologous superfamily	10 —

Domain ID domain_id	3ow2L00
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	1120 — Ribosomal protein L15e
Homologous superfamily homologous superfamily	10 — Ribosomal protein L15

Domain ID domain_id	3ow2M00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	420 — Nucleotidyltransferase; domain 5
Homologous superfamily homologous superfamily	100 —

Domain ID domain_id	3ow2N00
Class class	3 — Alpha Beta
Architecture architecture	100 — Ribosomal Protein L15; Chain: K; domain 2
Topology topology	10 — Ribosomal Protein L15; Chain: K; domain 2
Homologous superfamily homologous superfamily	10 —

Domain ID domain_id	3ow2O01
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	1650 — 50s Ribosomal Protein L19e, Chain O, domain 1
Homologous superfamily homologous superfamily	10 —

Domain ID domain_id	3ow2O02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	560 — Single Heli x bin

Domain ID domain_id	3ow2O03
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	1200 — Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A
Homologous superfamily homologous superfamily	60 —

Domain ID domain_id	3ow2P00
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	30 — SH3 type barrels.
Homologous superfamily homologous superfamily	70 — Ribosomal protein L21

Domain ID domain_id	3ow2Q00
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	470 — Ribosomal Protein L22; Chain A
Homologous superfamily homologous superfamily	10 — Ribosomal protein L22/L17

Domain ID domain_id	3ow2R00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	330 — RRM (RNA recognition motif) domain

Domain ID domain_id	3ow2S00
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	30 — SH3 type barrels.
Homologous superfamily homologous superfamily	30 —

Domain ID domain_id	3ow2T00
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	170 — Ribosomal Protein L24e; Chain: T;
Homologous superfamily homologous superfamily	20 — Ribosomal protein L24

Domain ID domain_id	3ow2U00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	287 — Helix Hairpins
Homologous superfamily homologous superfamily	310 —

Domain ID domain_id	3ow2V01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1390 — Ribosomal Protein L30; Chain: A,
Homologous superfamily homologous superfamily	20 — Ribosomal protein L30/L7

Domain ID domain_id	3ow2V02
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	15 — 3-methyladenine DNA Glycosylase II; Chain A, domain 3
Homologous superfamily homologous superfamily	30 — Ribosomal protein L30/L7, central domain

Domain ID domain_id	3ow2W00
Class class	3 — Alpha Beta
Architecture architecture	10 — Roll
Topology topology	440 — Ribosomal Protein L31e; Chain: W;
Homologous superfamily homologous superfamily	10 — Ribosomal protein L31

Domain ID domain_id	3ow2Y00
Class class	2 — Mainly Beta
Architecture architecture	20 — Single Sheet
Topology topology	25 — N-terminal domain of TfIIb
Homologous superfamily homologous superfamily	30 —

Domain ID domain_id	3ow2Z00
Class class	2 — Mainly Beta
Architecture architecture	20 — Single Sheet
Topology topology	25 — N-terminal domain of TfIIb
Homologous superfamily homologous superfamily	30 —

▶

Unit-cell length a length_a	211.853 Å
Unit-cell length b length_b	298.000 Å
Unit-cell length c length_c	574.985 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	8

Space group space_group	C 2 2 21
Space-group number int_tables_number	20
Crystal system crystal_system	—

Resolution resolution	2.700 Å
Low-resolution limit resolution_low	50.000 Å
R factor r_factor	—
R_work r_work	0.2215
R_free r_free	0.2527

Crystal Structure of Enhanced Macrolide Bound to 50S Ribosomal Subunit

1. Protein Identity and Related Structures Protein Identity & Related Structures

50S ribosomal protein L2P

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L3P

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L4P

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L5P

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L6P

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L7Ae

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L10E

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L13P

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L14P

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L15P

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer