Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | Transforming protein RhoA × 1 （P61586） | 与蛋白数一致 |
| 2 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | Transforming protein RhoA × 1 （P61586） | 与蛋白数一致 |
| UniProt名称 | ARHGB_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–410； UniProt 672–1081 作者链 E； PDB构建体 1–410； UniProt 672–1081 |
Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | Rho guanine nucleotide exchange factor 11 × 1 （O15085） | 与蛋白数一致 |
| 2 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | Rho guanine nucleotide exchange factor 11 × 1 （O15085） | 与蛋白数一致 |
| UniProt名称 | RHOA_HUMAN |
| Isoform | — |
| PDB实体 | 2 |
| 链与序列区间 | 作者链 B； PDB构建体 1–178； UniProt 3–180 作者链 F； PDB构建体 1–178； UniProt 3–180 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 3t06 |
| 沉积日期 deposition_date | 2011-07-19 |
| 结构标题 title | Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA |
| 关键词 keywords | DH-PH RhoA complex, PDZRhoGEF, GUANINE NUCLEOTIDE EXCHANGE FACTOR, RhoA, SIGNALING PROTEIN; SIGNALING PROTEIN |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 26.75 Å |
| Rg（电子密度） | 25.90 Å |
| 总 Rg | 26.73 Å |
| 原子数 | 4316 |
| 残基数 | 533 |
| 排除体积 | 77286 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d3t06a1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.87 — DBL homology domain (DH-domain) |
| 超家族 Superfamily superfamily | a.87.1 — DBL homology domain (DH-domain) |
| 家族 Family family | a.87.1.1 — DBL homology domain (DH-domain) |
| 结构域编号 domain_id | d3t06a2 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.55 — PH domain-like barrel |
| 超家族 Superfamily superfamily | b.55.1 — PH domain-like |
| 家族 Family family | b.55.1.1 — Pleckstrin-homology domain (PH domain) |
| 结构域编号 domain_id | d3t06b_ |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.8 — G proteins |
| 结构域编号 domain_id | d3t06e1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.87 — DBL homology domain (DH-domain) |
| 超家族 Superfamily superfamily | a.87.1 — DBL homology domain (DH-domain) |
| 家族 Family family | a.87.1.1 — DBL homology domain (DH-domain) |
| 结构域编号 domain_id | d3t06e2 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.55 — PH domain-like barrel |
| 超家族 Superfamily superfamily | b.55.1 — PH domain-like |
| 家族 Family family | b.55.1.1 — Pleckstrin-homology domain (PH domain) |
| 结构域编号 domain_id | d3t06f_ |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.8 — G proteins |
| 结构域编号 domain_id | 3t06A01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 900 — Dbl Homology Domain; Chain A |
| 同源超家族 H-superfamily homologous superfamily | 10 — Dbl homology (DH) domain |
| 结构域编号 domain_id | 3t06A02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 30 — Roll |
| 拓扑 Topology topology | 29 — PH-domain like |
| 同源超家族 H-superfamily homologous superfamily | 30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| 结构域编号 domain_id | 3t06B00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 3t06E01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 900 — Dbl Homology Domain; Chain A |
| 同源超家族 H-superfamily homologous superfamily | 10 — Dbl homology (DH) domain |
| 结构域编号 domain_id | 3t06E02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 30 — Roll |
| 拓扑 Topology topology | 29 — PH-domain like |
| 同源超家族 H-superfamily homologous superfamily | 30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| 结构域编号 domain_id | 3t06F00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |