Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | Cullin-3 × 1 （Q13618） | Consistent with protein count |
| UniProt name | KLHL3_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 25–277； UniProt 24–276 |
Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | Kelch-like protein 3 × 1 （Q9UH77） | Consistent with protein count |
| UniProt name | CUL3_HUMAN |
| Isoform | — |
| PDB entities | 2 |
| Chains and sequence ranges | Author chain B； PDBConstruct 25–386； UniProt 20–381 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 4hxi |
| Deposition date deposition_date | 2012-11-10 |
| Structure title title | Crystal structure of KLHL3/Cul3 complex |
| Keywords keywords | BTB-BACK, Protein-protein interaction, PROTEIN BINDING; PROTEIN BINDING |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 36.66 Å |
| Rg (electron density) | 36.90 Å |
| Total Rg | 36.96 Å |
| Atom count | 4339 |
| Residues | 538 |
| Excluded volume | 77280 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | 4hxiA01 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 710 — Potassium Channel Kv1.1; Chain A |
| Homologous superfamily homologous superfamily | 10 — Potassium Channel Kv1.1; Chain A |
| Domain ID domain_id | 4hxiA02 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 25 — Alpha Horseshoe |
| Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| Homologous superfamily homologous superfamily | 420 — |
| Domain ID domain_id | 4hxiB01 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1310 — 5 helical Cullin repeat like |
| Homologous superfamily homologous superfamily | 10 — Cullin Repeats |
| Domain ID domain_id | 4hxiB02 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1310 — 5 helical Cullin repeat like |
| Homologous superfamily homologous superfamily | 10 — Cullin Repeats |
| Domain ID domain_id | 4hxiB03 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1310 — 5 helical Cullin repeat like |
| Homologous superfamily homologous superfamily | 10 — Cullin Repeats |