Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein–RNA | Monomer | Protein 1 RNA 1 | RNA × 1 water × 2 | Consistent with all polymers |
| UniProt name | AGO1_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 6–862； UniProt 1–857 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 4kxt |
| Deposition date deposition_date | 2013-05-28 |
| Structure title title | Structure of human ARGONAUTE1 in complex with guide RNA |
| Keywords keywords | RNase H fold, nuclease, RNA, HYDROLASE-RNA complex; HYDROLASE/RNA |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 30.59 Å |
| Rg (electron density) | 29.99 Å |
| Total Rg | 30.68 Å |
| Atom count | 6695 |
| Residues | 818 |
| Excluded volume | 118990 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d4kxta1 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.34 — SH3-like barrel |
| Superfamily Superfamily superfamily | b.34.14 — PAZ domain |
| Family Family family | b.34.14.0 — automated matches |
| Domain ID domain_id | d4kxta2 |
| Class class | c — Alpha and beta proteins (a/b) |
| Fold Fold fold | c.44 — Phosphotyrosine protein phosphatases I-like |
| Superfamily Superfamily superfamily | c.44.3 — PIWI domain N-terminal-like |
| Family Family family | c.44.3.0 — automated matches |
| Domain ID domain_id | d4kxta3 |
| Class class | c — Alpha and beta proteins (a/b) |
| Fold Fold fold | c.55 — Ribonuclease H-like motif |
| Superfamily Superfamily superfamily | c.55.3 — Ribonuclease H-like |
| Family Family family | c.55.3.0 — automated matches |
| Domain ID domain_id | 4kxtA02 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 170 — Beta Complex |
| Topology topology | 260 — paz domain |
| Homologous superfamily homologous superfamily | 10 — paz domain |
| Domain ID domain_id | 4kxtA03 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| Topology topology | 50 — Rossmann fold |
| Homologous superfamily homologous superfamily | 2300 — Response regulator |
| Domain ID domain_id | 4kxtA04 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 420 — Nucleotidyltransferase; domain 5 |
| Homologous superfamily homologous superfamily | 10 — Ribonuclease H-like superfamily/Ribonuclease H |