4mey

Crystal structure of Escherichia coli RNA polymerase holoenzyme

Method: X-RAY DIFFRACTION Dmax: 277.5 Å Quality: GOOD

1. 蛋白身份与相关结构 Protein Identity & Related Structures

DNA-directed RNA polymerase subunit alpha

Escherichia coli

UniProt P0A7Z4

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 6 PDB 声明:hexameric(6) 与蛋白拷贝数一致 链 A; UniProt 1–329 链 B; UniProt 1–329 未记录 DNA-directed RNA polymerase subunit beta × 1 (P0A8V2) ;DNA-directed RNA polymerase subunit beta' ; × 1 (P0A8T7) DNA-directed RNA polymerase subunit omega × 1 (P0A800) RNA polymerase sigma factor RpoD × 1 (P00579) MG MAGNESIUM ION × 1 ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION, HANGING DROP;pH 7;295 K;0.1M HEPES, 0.2M calcium chloride, 18% PEG400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K 分辨率 3.95 Å R-free 0.325
2 蛋白异源复合物 异源复合物 蛋白 × 6 PDB 声明:hexameric(6) 与蛋白拷贝数一致 链 G; UniProt 1–329 链 H; UniProt 1–329 未记录 DNA-directed RNA polymerase subunit beta × 1 (P0A8V2) ;DNA-directed RNA polymerase subunit beta' ; × 1 (P0A8T7) DNA-directed RNA polymerase subunit omega × 1 (P0A800) RNA polymerase sigma factor RpoD × 1 (P00579) MG MAGNESIUM ION × 1 ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION, HANGING DROP;pH 7;295 K;0.1M HEPES, 0.2M calcium chloride, 18% PEG400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K 分辨率 3.95 Å R-free 0.325

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 276 个其他 PDB 条目、304 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 RPOA_ECOLI
Isoform
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–335; UniProt 1–329 作者链 B; PDB构建体 1–335; UniProt 1–329 作者链 G; PDB构建体 1–335; UniProt 1–329 作者链 H; PDB构建体 1–335; UniProt 1–329

DNA-directed RNA polymerase subunit beta

Escherichia coli

UniProt P0A8V2

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 6 PDB 声明:hexameric(6) 与蛋白拷贝数一致 链 C; UniProt 1–1342 未记录 DNA-directed RNA polymerase subunit alpha × 2 (P0A7Z4) ;DNA-directed RNA polymerase subunit beta' ; × 1 (P0A8T7) DNA-directed RNA polymerase subunit omega × 1 (P0A800) RNA polymerase sigma factor RpoD × 1 (P00579) MG MAGNESIUM ION × 1 ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION, HANGING DROP;pH 7;295 K;0.1M HEPES, 0.2M calcium chloride, 18% PEG400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K 分辨率 3.95 Å R-free 0.325
2 蛋白异源复合物 异源复合物 蛋白 × 6 PDB 声明:hexameric(6) 与蛋白拷贝数一致 链 I; UniProt 1–1342 未记录 DNA-directed RNA polymerase subunit alpha × 2 (P0A7Z4) ;DNA-directed RNA polymerase subunit beta' ; × 1 (P0A8T7) DNA-directed RNA polymerase subunit omega × 1 (P0A800) RNA polymerase sigma factor RpoD × 1 (P00579) MG MAGNESIUM ION × 1 ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION, HANGING DROP;pH 7;295 K;0.1M HEPES, 0.2M calcium chloride, 18% PEG400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K 分辨率 3.95 Å R-free 0.325

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 219 个其他 PDB 条目、239 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 RPOB_ECOLI
Isoform
PDB实体 2
链与序列区间 作者链 C; PDB构建体 1–1342; UniProt 1–1342 作者链 I; PDB构建体 1–1342; UniProt 1–1342

;DNA-directed RNA polymerase subunit beta' ;

Escherichia coli

UniProt P0A8T7

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 6 PDB 声明:hexameric(6) 与蛋白拷贝数一致 链 D; UniProt 1–1407 未记录 DNA-directed RNA polymerase subunit alpha × 2 (P0A7Z4) DNA-directed RNA polymerase subunit beta × 1 (P0A8V2) DNA-directed RNA polymerase subunit omega × 1 (P0A800) RNA polymerase sigma factor RpoD × 1 (P00579) MG MAGNESIUM ION × 1 ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION, HANGING DROP;pH 7;295 K;0.1M HEPES, 0.2M calcium chloride, 18% PEG400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K 分辨率 3.95 Å R-free 0.325
2 蛋白异源复合物 异源复合物 蛋白 × 6 PDB 声明:hexameric(6) 与蛋白拷贝数一致 链 J; UniProt 1–1407 未记录 DNA-directed RNA polymerase subunit alpha × 2 (P0A7Z4) DNA-directed RNA polymerase subunit beta × 1 (P0A8V2) DNA-directed RNA polymerase subunit omega × 1 (P0A800) RNA polymerase sigma factor RpoD × 1 (P00579) MG MAGNESIUM ION × 1 ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION, HANGING DROP;pH 7;295 K;0.1M HEPES, 0.2M calcium chloride, 18% PEG400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K 分辨率 3.95 Å R-free 0.325

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 239 个其他 PDB 条目、274 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 RPOC_ECOLI
Isoform
PDB实体 3
链与序列区间 作者链 D; PDB构建体 1–1407; UniProt 1–1407 作者链 J; PDB构建体 1–1407; UniProt 1–1407

DNA-directed RNA polymerase subunit omega

Escherichia coli

UniProt P0A800

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 6 PDB 声明:hexameric(6) 与蛋白拷贝数一致 链 E; UniProt 1–91 未记录 DNA-directed RNA polymerase subunit alpha × 2 (P0A7Z4) DNA-directed RNA polymerase subunit beta × 1 (P0A8V2) ;DNA-directed RNA polymerase subunit beta' ; × 1 (P0A8T7) RNA polymerase sigma factor RpoD × 1 (P00579) MG MAGNESIUM ION × 1 ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION, HANGING DROP;pH 7;295 K;0.1M HEPES, 0.2M calcium chloride, 18% PEG400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K 分辨率 3.95 Å R-free 0.325
2 蛋白异源复合物 异源复合物 蛋白 × 6 PDB 声明:hexameric(6) 与蛋白拷贝数一致 链 K; UniProt 1–91 未记录 DNA-directed RNA polymerase subunit alpha × 2 (P0A7Z4) DNA-directed RNA polymerase subunit beta × 1 (P0A8V2) ;DNA-directed RNA polymerase subunit beta' ; × 1 (P0A8T7) RNA polymerase sigma factor RpoD × 1 (P00579) MG MAGNESIUM ION × 1 ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION, HANGING DROP;pH 7;295 K;0.1M HEPES, 0.2M calcium chloride, 18% PEG400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K 分辨率 3.95 Å R-free 0.325

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 258 个其他 PDB 条目、276 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 RPOZ_ECOLI
Isoform
PDB实体 4
链与序列区间 作者链 E; PDB构建体 1–91; UniProt 1–91 作者链 K; PDB构建体 1–91; UniProt 1–91

RNA polymerase sigma factor RpoD

Escherichia coli

UniProt P00579

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 6 PDB 声明:hexameric(6) 与蛋白拷贝数一致 链 F; UniProt 1–613 未记录 DNA-directed RNA polymerase subunit alpha × 2 (P0A7Z4) DNA-directed RNA polymerase subunit beta × 1 (P0A8V2) ;DNA-directed RNA polymerase subunit beta' ; × 1 (P0A8T7) DNA-directed RNA polymerase subunit omega × 1 (P0A800) MG MAGNESIUM ION × 1 ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION, HANGING DROP;pH 7;295 K;0.1M HEPES, 0.2M calcium chloride, 18% PEG400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K 分辨率 3.95 Å R-free 0.325
2 蛋白异源复合物 异源复合物 蛋白 × 6 PDB 声明:hexameric(6) 与蛋白拷贝数一致 链 L; UniProt 1–613 未记录 DNA-directed RNA polymerase subunit alpha × 2 (P0A7Z4) DNA-directed RNA polymerase subunit beta × 1 (P0A8V2) ;DNA-directed RNA polymerase subunit beta' ; × 1 (P0A8T7) DNA-directed RNA polymerase subunit omega × 1 (P0A800) MG MAGNESIUM ION × 1 ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION, HANGING DROP;pH 7;295 K;0.1M HEPES, 0.2M calcium chloride, 18% PEG400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K 分辨率 3.95 Å R-free 0.325

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 91 个其他 PDB 条目、131 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 RPOD_ECOLI
Isoform
PDB实体 5
链与序列区间 作者链 F; PDB构建体 1–613; UniProt 1–613 作者链 L; PDB构建体 1–613; UniProt 1–613

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

SAXS 散射曲线 SAXS Profile

SAXS profile for 4mey

P(r) 距离分布 P(r) Distribution

P(r) distribution for 4mey
下载 Download

2. 结构基本信息 2. Structure Basics

条目编号 entry_id4mey
沉积日期 deposition_date2013-08-27
结构标题 titleCrystal structure of Escherichia coli RNA polymerase holoenzyme
关键词 keywordsRNA polymerase, DNA Binding, TRANSFERASE; TRANSFERASE
实验方法 methodX-RAY DIFFRACTION

3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier74.19
回转半径 Rg (电子) rg_electron74.35
零角强度 I(0) i07276060000.00
分子量 molecular_weight705590.0 kDa
排除体积 excluded_volume874980 ų
包络体积 envelope_volume1608500 ų
水化壳体积 shell_volume177140 ų
包络直径 envelope_diameter264.5
壳层 Rg shell_rg75.79
包络 Rg envelope_rg71.22
形状 Rg shape_rg74.29
总 Rg total_rg74.55
总原子数 total_atoms49826
残基数 n_residues7075
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax277.5
Rg (实空间) rg_real78.64
Rg 误差 (实空间) rg_real_error2.17
I(0) (实空间) i0_real7.3390e+09
I(0) 误差 (实空间) i0_real_error1.7410e+08
Rg (倒空间) rg_reciprocal74.24
I(0) (倒空间) i0_reciprocal7277000000.0000
解质量估计 total_estimate0.8818
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks1
主峰位置 r_peak_primary79.3
偏度 Skewness skewness0.523
峰度 Kurtosis kurtosis0.032
角度范围 angular_range— – 0.1050 −1
当前正则化参数 α current_alpha0.9517
最高正则化参数 α highest_alpha1194000000.0000
实空间数据点数 n_real_points22
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.751; Stabil: 0.836; Sysdev: 1.000; Positv: 1.000; Valcen: 0.995; Smooth: 0.756

5. 晶体学与实验 5. Crystallography & Experiment

6. 实体与聚合物信息 Entities & Polymers (7)

7. 折叠分类 (SCOP + CATH) 32 domains

CATH v4.4 (32 domains)

结构域编号 domain_id4meyA01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1360 — Gyrase A; domain 2
同源超家族 H-superfamily homologous superfamily10 — RNA polymerase, RBP11-like subunit
结构域编号 domain_id4meyA02
类 Class class2 — Mainly Beta
架构 Architecture architecture170 — Beta Complex
拓扑 Topology topology120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
同源超家族 H-superfamily homologous superfamily12 — DNA-directed RNA polymerase, insert domain
结构域编号 domain_id4meyA03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology150 — DNA polymerase; domain 1
同源超家族 H-superfamily homologous superfamily20 — 5' to 3' exonuclease, C-terminal subdomain
结构域编号 domain_id4meyB01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1360 — Gyrase A; domain 2
同源超家族 H-superfamily homologous superfamily10 — RNA polymerase, RBP11-like subunit
结构域编号 domain_id4meyB02
类 Class class2 — Mainly Beta
架构 Architecture architecture170 — Beta Complex
拓扑 Topology topology120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
同源超家族 H-superfamily homologous superfamily12 — DNA-directed RNA polymerase, insert domain
结构域编号 domain_id4meyB03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology150 — DNA polymerase; domain 1
同源超家族 H-superfamily homologous superfamily20 — 5' to 3' exonuclease, C-terminal subdomain
结构域编号 domain_id4meyC02
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology1110 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3
同源超家族 H-superfamily homologous superfamily10 — RNA polymerase Rpb2, domain 2
结构域编号 domain_id4meyC04
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology150 — Rna Polymerase Beta Subunit; Chain: C, domain 4
同源超家族 H-superfamily homologous superfamily10 — DNA-directed RNA polymerase, beta subunit, external 1 domain
结构域编号 domain_id4meyC05
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology270 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6
同源超家族 H-superfamily homologous superfamily10 — DNA-directed RNA polymerase, subunit 2, domain 6
结构域编号 domain_id4meyC06
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id4meyC07
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily150 — RNA polymerase II, Rpb2 subunit, wall domain
结构域编号 domain_id4meyC08
类 Class class6 — Special
架构 Architecture architecture10 — Helix non-globular
拓扑 Topology topology140 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1670
结构域编号 domain_id4meyD01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology132 — Topoisomerase I; Chain A, domain 4
同源超家族 H-superfamily homologous superfamily30 — RNA polymerase Rpb1 funnel domain
结构域编号 domain_id4meyE00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology940 — Eukaryotic RPB6 RNA polymerase subunit
同源超家族 H-superfamily homologous superfamily10 — RNA polymerase subunit, RPB6/omega
结构域编号 domain_id4meyF01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology601 — RNA Polymerase Primary Sigma Factor
同源超家族 H-superfamily homologous superfamily10 — RNA Polymerase Primary Sigma Factor
结构域编号 domain_id4meyF02
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
结构域编号 domain_id4meyF03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
结构域编号 domain_id4meyG01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1360 — Gyrase A; domain 2
同源超家族 H-superfamily homologous superfamily10 — RNA polymerase, RBP11-like subunit
结构域编号 domain_id4meyG02
类 Class class2 — Mainly Beta
架构 Architecture architecture170 — Beta Complex
拓扑 Topology topology120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
同源超家族 H-superfamily homologous superfamily12 — DNA-directed RNA polymerase, insert domain
结构域编号 domain_id4meyH01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1360 — Gyrase A; domain 2
同源超家族 H-superfamily homologous superfamily10 — RNA polymerase, RBP11-like subunit
结构域编号 domain_id4meyH02
类 Class class2 — Mainly Beta
架构 Architecture architecture170 — Beta Complex
拓扑 Topology topology120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
同源超家族 H-superfamily homologous superfamily12 — DNA-directed RNA polymerase, insert domain
结构域编号 domain_id4meyI01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology270 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6
同源超家族 H-superfamily homologous superfamily10 — DNA-directed RNA polymerase, subunit 2, domain 6
结构域编号 domain_id4meyI03
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology1110 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3
同源超家族 H-superfamily homologous superfamily10 — RNA polymerase Rpb2, domain 2
结构域编号 domain_id4meyI05
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology150 — Rna Polymerase Beta Subunit; Chain: C, domain 4
同源超家族 H-superfamily homologous superfamily10 — DNA-directed RNA polymerase, beta subunit, external 1 domain
结构域编号 domain_id4meyI06
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id4meyI07
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily150 — RNA polymerase II, Rpb2 subunit, wall domain
结构域编号 domain_id4meyI08
类 Class class6 — Special
架构 Architecture architecture10 — Helix non-globular
拓扑 Topology topology140 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1670
结构域编号 domain_id4meyJ01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology132 — Topoisomerase I; Chain A, domain 4
同源超家族 H-superfamily homologous superfamily30 — RNA polymerase Rpb1 funnel domain
结构域编号 domain_id4meyK00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology940 — Eukaryotic RPB6 RNA polymerase subunit
同源超家族 H-superfamily homologous superfamily10 — RNA polymerase subunit, RPB6/omega
结构域编号 domain_id4meyL01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology601 — RNA Polymerase Primary Sigma Factor
同源超家族 H-superfamily homologous superfamily10 — RNA Polymerase Primary Sigma Factor
结构域编号 domain_id4meyL02
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
结构域编号 domain_id4meyL03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

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