4rsu

Crystal structure of the light and hvem complex

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Tumor necrosis factor ligand superfamily member 14, soluble form

Homo sapiens

UniProt O43557

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 Tumor necrosis factor receptor superfamily member 14 × 6 (Q92956) CHLORIDE ION × 14 GLYCEROL × 8 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 water × 12 与蛋白数一致
2 蛋白异源复合物 异源复合物 蛋白 6 Tumor necrosis factor receptor superfamily member 14 × 3 (Q92956) CHLORIDE ION × 7 GLYCEROL × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 water × 6 与蛋白数一致
3 蛋白异源复合物 异源复合物 蛋白 6 Tumor necrosis factor receptor superfamily member 14 × 3 (Q92956) CHLORIDE ION × 7 GLYCEROL × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 water × 6 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 TNF14_HUMAN
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 8–165; UniProt 83–240 作者链 B; PDB构建体 8–165; UniProt 83–240 作者链 C; PDB构建体 8–165; UniProt 83–240 作者链 G; PDB构建体 8–165; UniProt 83–240 作者链 H; PDB构建体 8–165; UniProt 83–240 作者链 I; PDB构建体 8–165; UniProt 83–240

Tumor necrosis factor receptor superfamily member 14

Homo sapiens

UniProt Q92956

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 Tumor necrosis factor ligand superfamily member 14, soluble form × 6 (O43557) CHLORIDE ION × 14 GLYCEROL × 8 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 water × 12 与蛋白数一致
2 蛋白异源复合物 异源复合物 蛋白 6 Tumor necrosis factor ligand superfamily member 14, soluble form × 3 (O43557) CHLORIDE ION × 7 GLYCEROL × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 water × 6 与蛋白数一致
3 蛋白异源复合物 异源复合物 蛋白 6 Tumor necrosis factor ligand superfamily member 14, soluble form × 3 (O43557) CHLORIDE ION × 7 GLYCEROL × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 water × 6 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 TNR14_HUMAN
Isoform —
PDB实体 2
链与序列区间 作者链 D; PDB构建体 3–126; UniProt 39–162 作者链 E; PDB构建体 3–126; UniProt 39–162 作者链 F; PDB构建体 3–126; UniProt 39–162 作者链 J; PDB构建体 3–126; UniProt 39–162 作者链 K; PDB构建体 3–126; UniProt 39–162 作者链 L; PDB构建体 3–126; UniProt 39–162

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id4rsu
沉积日期 deposition_date2014-11-11
结构标题 titleCrystal structure of the light and hvem complex
关键词 keywords;STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS, RESEARCH CONSORTIUM, NYSGRC, IMMUNITY, N-GLYCOSYLATION, MEMBRANE, SECRETED PROTEIN, CYTOKINE, IFN, JELLY-ROLL FOLD, Protein Structure Initiative, Atoms-to-Animals: The Immune Function Network, cysteine rich domain, signaling, cell membrane, secreted, IMMUNE SYSTEM, New York Structural Genomics Research Consortium ;; IMMUNE SYSTEM
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

4rsu__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

4rsu__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

4rsu__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)38.24 Å
Rg(电子密度)37.96 Å
总 Rg38.44 Å
原子数11330
残基数1496
排除体积200460 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 4rsu__assembly_1__model_1 dodecameric (12) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 4rsu__assembly_2__model_1 hexameric (6) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 4rsu__assembly_3__model_1 hexameric (6) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (6)

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6. 折叠分类 (SCOP + CATH) 41 domains

SCOP 2.08 (23 domains)

结构域编号 domain_idd4rsua_
类 Class classb — All beta proteins
折叠类型 Fold foldb.22 — TNF-like
超家族 Superfamily superfamilyb.22.1 — TNF-like
家族 Family familyb.22.1.0 — automated matches
结构域编号 domain_idd4rsub_
类 Class classb — All beta proteins
折叠类型 Fold foldb.22 — TNF-like
超家族 Superfamily superfamilyb.22.1 — TNF-like
家族 Family familyb.22.1.0 — automated matches
结构域编号 domain_idd4rsuc_
类 Class classb — All beta proteins
折叠类型 Fold foldb.22 — TNF-like
超家族 Superfamily superfamilyb.22.1 — TNF-like
家族 Family familyb.22.1.0 — automated matches
结构域编号 domain_idd4rsud1
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsud2
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsud3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd4rsue1
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsue2
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsue3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd4rsuf1
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsuf2
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsuf3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd4rsug_
类 Class classb — All beta proteins
折叠类型 Fold foldb.22 — TNF-like
超家族 Superfamily superfamilyb.22.1 — TNF-like
家族 Family familyb.22.1.0 — automated matches
结构域编号 domain_idd4rsuh_
类 Class classb — All beta proteins
折叠类型 Fold foldb.22 — TNF-like
超家族 Superfamily superfamilyb.22.1 — TNF-like
家族 Family familyb.22.1.0 — automated matches
结构域编号 domain_idd4rsui_
类 Class classb — All beta proteins
折叠类型 Fold foldb.22 — TNF-like
超家族 Superfamily superfamilyb.22.1 — TNF-like
家族 Family familyb.22.1.0 — automated matches
结构域编号 domain_idd4rsuj1
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsuj2
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsuj3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd4rsuk1
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsuk2
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsuk3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd4rsul1
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like
结构域编号 domain_idd4rsul2
类 Class classg — Small proteins
折叠类型 Fold foldg.24 — TNF receptor-like
超家族 Superfamily superfamilyg.24.1 — TNF receptor-like
家族 Family familyg.24.1.1 — TNF receptor-like

CATH v4.4 (18 domains)

结构域编号 domain_id4rsuA00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily40 —
结构域编号 domain_id4rsuB00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily40 —
结构域编号 domain_id4rsuC00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily40 —
结构域编号 domain_id4rsuD01
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuD02
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuE01
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuE02
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuF01
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuF02
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuG00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily40 —
结构域编号 domain_id4rsuH00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily40 —
结构域编号 domain_id4rsuI00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily40 —
结构域编号 domain_id4rsuJ01
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuJ02
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuK01
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuK02
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuL01
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4rsuL02
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
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7. 引用文献 (1)