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4wzs

Crystal structure of the Mot1 N-terminal domain in complex with TBP and NC2 bound to a promoter DNA fragment

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

ECU11_1470 protein

Encephalitozoon cuniculi (strain GB-M1)

UniProt Q8SQT6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 4 DNA 2 TATA-binding protein-associated phosphoprotein × 1 （M1K2J7） Similarity to HELICASE MOT1 × 1 （Q8SVZ5） ECU04_1440 protein × 1 （Q8ST28） ;DNA (5'-D(P*CP*CP*AP*CP*CP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*CP*T)-3') ; × 1 ;DNA (5'-D(P*GP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*GP*GP*TP*GP*G)-3') ; × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
4wzs

1 assemblies

View Construct and Data Evidence
UniProt name Q8SQT6_ENCCU
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–95； UniProt 2–95

TATA-binding protein-associated phosphoprotein

Encephalitozoon cuniculi

UniProt M1K2J7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 4 DNA 2 ECU11_1470 protein × 1 （Q8SQT6） Similarity to HELICASE MOT1 × 1 （Q8SVZ5） ECU04_1440 protein × 1 （Q8ST28） ;DNA (5'-D(P*CP*CP*AP*CP*CP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*CP*T)-3') ; × 1 ;DNA (5'-D(P*GP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*GP*GP*TP*GP*G)-3') ; × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
4wzs

1 assemblies

View Construct and Data Evidence
UniProt name M1K2J7_ENCCN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 4–149； UniProt 2–147

Similarity to HELICASE MOT1

Encephalitozoon cuniculi (strain GB-M1)

UniProt Q8SVZ5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 4 DNA 2 ECU11_1470 protein × 1 （Q8SQT6） TATA-binding protein-associated phosphoprotein × 1 （M1K2J7） ECU04_1440 protein × 1 （Q8ST28） ;DNA (5'-D(P*CP*CP*AP*CP*CP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*CP*T)-3') ; × 1 ;DNA (5'-D(P*GP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*GP*GP*TP*GP*G)-3') ; × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3oc3 3oc3 4wzs

3 assemblies

View Construct and Data Evidence
UniProt name Q8SVZ5_ENCCU
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 4–780； UniProt 2–778

ECU04_1440 protein

Encephalitozoon cuniculi (strain GB-M1)

UniProt Q8ST28

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 4 DNA 2 ECU11_1470 protein × 1 （Q8SQT6） TATA-binding protein-associated phosphoprotein × 1 （M1K2J7） Similarity to HELICASE MOT1 × 1 （Q8SVZ5） ;DNA (5'-D(P*CP*CP*AP*CP*CP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*CP*T)-3') ; × 1 ;DNA (5'-D(P*GP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*GP*GP*TP*GP*G)-3') ; × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer
3eik 3oci

2 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3oc3 3oc3 4wzs

3 assemblies

View Construct and Data Evidence
UniProt name Q8ST28_ENCCU
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D； PDBConstruct 4–200； UniProt 2–198

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id4wzs
Deposition date deposition_date2014-11-20
Structure title titleCrystal structure of the Mot1 N-terminal domain in complex with TBP and NC2 bound to a promoter DNA fragment
Keywords keywordsTranscription, protein-DNA complex, Swi2/Snf2; TRANSCRIPTION
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4wzs__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4wzs__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

4wzs__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）37.02 Å
Rg (electron density)36.24 Å
Total Rg36.70 Å
Atom count9037
Residues1093
Excluded volume159230 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 4wzs__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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6. Fold Classification (SCOP + CATH) 3 domains

CATH v4.4 (3 domains)

Domain ID domain_id4wzsB00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology20 — Histone, subunit A
Homologous superfamily homologous superfamily10 — Histone, subunit A
Domain ID domain_id4wzsD01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology310 — TATA-Binding Protein
Homologous superfamily homologous superfamily10 — TATA-Binding Protein
Domain ID domain_id4wzsD02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology310 — TATA-Binding Protein
Homologous superfamily homologous superfamily10 — TATA-Binding Protein
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7. Citations (1)