5anb

Mechanism of eIF6 release from the nascent 60S ribosomal subunit

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

60S RIBOSOMAL PROTEIN L3

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L9 × 1 （Q54XI5） 60S ACIDIC RIBOSOMAL PROTEIN P0 × 1 （P22685） 60S RIBOSOMAL PROTEIN L12 × 1 （Q54J50） 60S RIBOSOMAL PROTEIN L23 × 1 （Q54G86） 60S RIBOSOMAL PROTEIN L10 × 1 （Q54J69） 60S RIBOSOMAL PROTEIN L24 × 1 （Q54VN6） UBIQUITIN-60S RIBOSOMAL PROTEIN L40 × 1 （P14794） EUKARYOTIC TRANSLATION INITIATION FACTOR 6 × 1 （Q551M2） RIBOSOME MATURATION PROTEIN SBDS × 1 （Q9Y3A5） ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 × 1 （Q7Z2Z2） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL3_DICDI
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–398； UniProt 1–398

60S RIBOSOMAL PROTEIN L9

OrganismNot specified

UniProt Q54XI5

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L3 × 1 （P34113） 60S ACIDIC RIBOSOMAL PROTEIN P0 × 1 （P22685） 60S RIBOSOMAL PROTEIN L12 × 1 （Q54J50） 60S RIBOSOMAL PROTEIN L23 × 1 （Q54G86） 60S RIBOSOMAL PROTEIN L10 × 1 （Q54J69） 60S RIBOSOMAL PROTEIN L24 × 1 （Q54VN6） UBIQUITIN-60S RIBOSOMAL PROTEIN L40 × 1 （P14794） EUKARYOTIC TRANSLATION INITIATION FACTOR 6 × 1 （Q551M2） RIBOSOME MATURATION PROTEIN SBDS × 1 （Q9Y3A5） ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 × 1 （Q7Z2Z2） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL9_DICDI
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 1–188； UniProt 1–188

60S ACIDIC RIBOSOMAL PROTEIN P0

OrganismNot specified

UniProt P22685

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L3 × 1 （P34113） 60S RIBOSOMAL PROTEIN L9 × 1 （Q54XI5） 60S RIBOSOMAL PROTEIN L12 × 1 （Q54J50） 60S RIBOSOMAL PROTEIN L23 × 1 （Q54G86） 60S RIBOSOMAL PROTEIN L10 × 1 （Q54J69） 60S RIBOSOMAL PROTEIN L24 × 1 （Q54VN6） UBIQUITIN-60S RIBOSOMAL PROTEIN L40 × 1 （P14794） EUKARYOTIC TRANSLATION INITIATION FACTOR 6 × 1 （Q551M2） RIBOSOME MATURATION PROTEIN SBDS × 1 （Q9Y3A5） ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 × 1 （Q7Z2Z2） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RLA0_DICDI
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain C； PDBConstruct 1–205； UniProt 1–205

60S RIBOSOMAL PROTEIN L12

OrganismNot specified

UniProt Q54J50

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L3 × 1 （P34113） 60S RIBOSOMAL PROTEIN L9 × 1 （Q54XI5） 60S ACIDIC RIBOSOMAL PROTEIN P0 × 1 （P22685） 60S RIBOSOMAL PROTEIN L23 × 1 （Q54G86） 60S RIBOSOMAL PROTEIN L10 × 1 （Q54J69） 60S RIBOSOMAL PROTEIN L24 × 1 （Q54VN6） UBIQUITIN-60S RIBOSOMAL PROTEIN L40 × 1 （P14794） EUKARYOTIC TRANSLATION INITIATION FACTOR 6 × 1 （Q551M2） RIBOSOME MATURATION PROTEIN SBDS × 1 （Q9Y3A5） ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 × 1 （Q7Z2Z2） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL12_DICDI
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain D； PDBConstruct 1–166； UniProt 1–166

60S RIBOSOMAL PROTEIN L23

OrganismNot specified

UniProt Q54G86

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L3 × 1 （P34113） 60S RIBOSOMAL PROTEIN L9 × 1 （Q54XI5） 60S ACIDIC RIBOSOMAL PROTEIN P0 × 1 （P22685） 60S RIBOSOMAL PROTEIN L12 × 1 （Q54J50） 60S RIBOSOMAL PROTEIN L10 × 1 （Q54J69） 60S RIBOSOMAL PROTEIN L24 × 1 （Q54VN6） UBIQUITIN-60S RIBOSOMAL PROTEIN L40 × 1 （P14794） EUKARYOTIC TRANSLATION INITIATION FACTOR 6 × 1 （Q551M2） RIBOSOME MATURATION PROTEIN SBDS × 1 （Q9Y3A5） ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 × 1 （Q7Z2Z2） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL23_DICDI
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain E； PDBConstruct 1–136； UniProt 1–136

60S RIBOSOMAL PROTEIN L10

OrganismNot specified

UniProt Q54J69

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L3 × 1 （P34113） 60S RIBOSOMAL PROTEIN L9 × 1 （Q54XI5） 60S ACIDIC RIBOSOMAL PROTEIN P0 × 1 （P22685） 60S RIBOSOMAL PROTEIN L12 × 1 （Q54J50） 60S RIBOSOMAL PROTEIN L23 × 1 （Q54G86） 60S RIBOSOMAL PROTEIN L24 × 1 （Q54VN6） UBIQUITIN-60S RIBOSOMAL PROTEIN L40 × 1 （P14794） EUKARYOTIC TRANSLATION INITIATION FACTOR 6 × 1 （Q551M2） RIBOSOME MATURATION PROTEIN SBDS × 1 （Q9Y3A5） ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 × 1 （Q7Z2Z2） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL10_DICDI
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain F； PDBConstruct 1–217； UniProt 1–217

60S RIBOSOMAL PROTEIN L24

OrganismNot specified

UniProt Q54VN6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L3 × 1 （P34113） 60S RIBOSOMAL PROTEIN L9 × 1 （Q54XI5） 60S ACIDIC RIBOSOMAL PROTEIN P0 × 1 （P22685） 60S RIBOSOMAL PROTEIN L12 × 1 （Q54J50） 60S RIBOSOMAL PROTEIN L23 × 1 （Q54G86） 60S RIBOSOMAL PROTEIN L10 × 1 （Q54J69） UBIQUITIN-60S RIBOSOMAL PROTEIN L40 × 1 （P14794） EUKARYOTIC TRANSLATION INITIATION FACTOR 6 × 1 （Q551M2） RIBOSOME MATURATION PROTEIN SBDS × 1 （Q9Y3A5） ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 × 1 （Q7Z2Z2） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL24_DICDI
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain G； PDBConstruct 1–69； UniProt 1–69

UBIQUITIN-60S RIBOSOMAL PROTEIN L40

OrganismNot specified

UniProt P14794

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L3 × 1 （P34113） 60S RIBOSOMAL PROTEIN L9 × 1 （Q54XI5） 60S ACIDIC RIBOSOMAL PROTEIN P0 × 1 （P22685） 60S RIBOSOMAL PROTEIN L12 × 1 （Q54J50） 60S RIBOSOMAL PROTEIN L23 × 1 （Q54G86） 60S RIBOSOMAL PROTEIN L10 × 1 （Q54J69） 60S RIBOSOMAL PROTEIN L24 × 1 （Q54VN6） EUKARYOTIC TRANSLATION INITIATION FACTOR 6 × 1 （Q551M2） RIBOSOME MATURATION PROTEIN SBDS × 1 （Q9Y3A5） ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 × 1 （Q7Z2Z2） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL40_DICDI
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain H； PDBConstruct 1–52； UniProt 77–128

EUKARYOTIC TRANSLATION INITIATION FACTOR 6

OrganismNot specified

UniProt Q551M2

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L3 × 1 （P34113） 60S RIBOSOMAL PROTEIN L9 × 1 （Q54XI5） 60S ACIDIC RIBOSOMAL PROTEIN P0 × 1 （P22685） 60S RIBOSOMAL PROTEIN L12 × 1 （Q54J50） 60S RIBOSOMAL PROTEIN L23 × 1 （Q54G86） 60S RIBOSOMAL PROTEIN L10 × 1 （Q54J69） 60S RIBOSOMAL PROTEIN L24 × 1 （Q54VN6） UBIQUITIN-60S RIBOSOMAL PROTEIN L40 × 1 （P14794） RIBOSOME MATURATION PROTEIN SBDS × 1 （Q9Y3A5） ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 × 1 （Q7Z2Z2） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	IF6_DICDI
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain I； PDBConstruct 1–224； UniProt 1–224

RIBOSOME MATURATION PROTEIN SBDS

HOMO SAPIENS

UniProt Q9Y3A5

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L3 × 1 （P34113） 60S RIBOSOMAL PROTEIN L9 × 1 （Q54XI5） 60S ACIDIC RIBOSOMAL PROTEIN P0 × 1 （P22685） 60S RIBOSOMAL PROTEIN L12 × 1 （Q54J50） 60S RIBOSOMAL PROTEIN L23 × 1 （Q54G86） 60S RIBOSOMAL PROTEIN L10 × 1 （Q54J69） 60S RIBOSOMAL PROTEIN L24 × 1 （Q54VN6） UBIQUITIN-60S RIBOSOMAL PROTEIN L40 × 1 （P14794） EUKARYOTIC TRANSLATION INITIATION FACTOR 6 × 1 （Q551M2） ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 × 1 （Q7Z2Z2） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	SBDS_HUMAN
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain J； PDBConstruct 1–250； UniProt 1–250

ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1

HOMO SAPIENS

UniProt Q7Z2Z2

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 11 RNA 1	60S RIBOSOMAL PROTEIN L3 × 1 （P34113） 60S RIBOSOMAL PROTEIN L9 × 1 （Q54XI5） 60S ACIDIC RIBOSOMAL PROTEIN P0 × 1 （P22685） 60S RIBOSOMAL PROTEIN L12 × 1 （Q54J50） 60S RIBOSOMAL PROTEIN L23 × 1 （Q54G86） 60S RIBOSOMAL PROTEIN L10 × 1 （Q54J69） 60S RIBOSOMAL PROTEIN L24 × 1 （Q54VN6） UBIQUITIN-60S RIBOSOMAL PROTEIN L40 × 1 （P14794） EUKARYOTIC TRANSLATION INITIATION FACTOR 6 × 1 （Q551M2） RIBOSOME MATURATION PROTEIN SBDS × 1 （Q9Y3A5） 26S RIBOSOMAL RNA × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	ETUD1_HUMAN
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain K； PDBConstruct 1–1120； UniProt 1–1120

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	5anb
Deposition date deposition_date	2015-09-06
Structure title title	Mechanism of eIF6 release from the nascent 60S ribosomal subunit
Keywords keywords	TRANSLATION, RIBOSOMOPATHY, GTPASE, RIBOSOME BIOGENESIS; TRANSLATION
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5anb__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5anb__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

5anb__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	61.26 Å
Rg (electron density)	61.48 Å
Total Rg	61.55 Å
Atom count	48493
Residues	4187
Excluded volume	776050 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`5anb__assembly_1__model_1`	dodecameric （12）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (12)

Entity 1 Entity 1 polymer

Description description	60S RIBOSOMAL PROTEIN L3
Molecular weight formula_weight	45158.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A
Atom count atom_count	48493

MSHRKFEAPRHGNLGFRPRKRAARHQGKVKSFPKDDRTQKVHLTAFMGYKAGMTHVVRDLEKPGSKMHKKEIVEAVTIIECPPMYIVGLVGYVETAQGLKTYKTVWAQHLSDNFRRRLYKNWYKSKSKKAFTKYVKQYETEEGKKSIEASLQAIKKRCSVVRVIAHTQVHKLKLTQKKAHVLEIQVNGGSIVEKVNFAVANFEKTVNVTGVFAENELIDVIGVTKGKGFNGVIKRWGVRKLPRKTHKGLRKVACIGAWHPSRVSTTVPRAGQLGYHHRVERNKKIYRIGQAQPEDGKQISTGKTEFDLTEKTINPMGGFAHYGMVKHEFLMLKGCVAGPRKRALTLRKSITTQTGRAALEKITLKFIDTSSKFGHGLHQTAEDKTKYFGVKKSRSTKA

Entity 2 Entity 2 polymer

Description description	60S RIBOSOMAL PROTEIN L9
Molecular weight formula_weight	21250.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

MKVINSSRKVQIPENVTVDVKGRSVKVTGPRGTLSKSFDHASVDINLVGKKELTVDLWFGNRKQIACIKTITSIIENMITGVTKGYEYKMRFVYAHFPINVAVTDGGRVVEIRNFFGEKIVRRIELLDGITCYRNEKAKDEIVLTGNSLELLSQSCATIQLRSAIKYKDVRKFLDGIYVSERNVLESN

Entity 3 Entity 3 polymer

Description description	60S ACIDIC RIBOSOMAL PROTEIN P0
Molecular weight formula_weight	22434.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

MSGAGSKRKNVFIEKATKLFTTYDKMIVAEADFVGSSQLQKIRKSIRGIGAVLMGKKTMIRKVIRDLADSKPELDALNTYLKQNTCIIFCKDNIAEVKRVINTQRVGAPAKAGVFAPNDVIIPAGPTGMEPTQTSFLQDLKIATKINRGQIDIVNEVHIIKTGQKVGASEATLLQKLNIKPFTYGLEPKIIYDAGACYSPSISEE

Entity 4 Entity 4 polymer

Description description	60S RIBOSOMAL PROTEIN L12
Molecular weight formula_weight	17811.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D

MPPKVDPSEKVEVFLRVCGGEAGAMSTLAPKLGPLGVSPKKVGDDIAKATQPWKGMKVSVKLTIQNRIAVPEVLPSASALVIKALKEPPRDRKKEKNIKHNGNIPLEEICKIAKTMRFKSLAVDFKGSVLEILGTAHSVGCKVNGKSPRDIQAGIQSGEIEVVEPK

Entity 5 Entity 5 polymer

Description description	60S RIBOSOMAL PROTEIN L23
Molecular weight formula_weight	14567.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

MSKAQAVGSNYRVSLGLPVGAVMNSADNSGAKNLYVIAVKGIKGRLNRLPSAGVGDMVMATVKKGKPELRKKVCTGLVVRQRKHWKRKDGVYIYFEDNAGVMCNPKGEVKGNILGPVAKECSDLWPKVATNAGTIV

Entity 6 Entity 6 polymer

Description description	60S RIBOSOMAL PROTEIN L10
Molecular weight formula_weight	24591.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F

MGRRPARCYRYCKNKPYIKSRYCRGVPDAKIRIFDLGRKKASTDEFPLCVHLISLEKEQLSSEAIEAGRISCNKYISKTGGKDSFHMRVRVHPWHVLRINKMLSCAGADRLQTGMRGAFGKPMGTVARVNIGQIIFSIRTRDNMLANVVEALRRSSYKFPGRQKIVVSKKWGFTAYNREAYQKLKADGRLMNDGANVKVITNHGTLAQYAKDIAAAN

Entity 7 Entity 7 polymer

Description description	60S RIBOSOMAL PROTEIN L24
Molecular weight formula_weight	8334.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G

MKTSLCNYSEFKIYPARGMKFVRGDSKVFHFINTKVESLFFRKINPRDIRWSMVYRRIYKNTTTDVSAK

Entity 8 Entity 8 polymer

Description description	UBIQUITIN-60S RIBOSOMAL PROTEIN L40
Molecular weight formula_weight	6170.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

IEPSLVILARKYKCDKMICRKCYARLHPRAVNCRKKKCGHSNNLRPKKKLLK

Entity 9 Entity 9 polymer

Description description	EUKARYOTIC TRANSLATION INITIATION FACTOR 6
Molecular weight formula_weight	24107.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

MATRLQYENSCDVGVFLKLTNKYCLVGQCGSKQFLHTVENRLADHIPVVETSIAGTRIVGRLSAGNKNGLLLPNTCTDQELQQIRNSLPDDVVVQRIEEKFSALGNCIATNDYVALVHPDIDRETEEIIADVLGVEVFRQTVSGNVLVGTYCALTNQGALVHPMTSIADQDELSSLLQVPLVAGTVNRGNECVAAGCVVNDWTAIVGADTTATEISVIESIFAL

Entity 10 Entity 10 polymer

Description description	RIBOSOME MATURATION PROTEIN SBDS
Molecular weight formula_weight	28813.6 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J

MSIFTPTNQIRLTNVAVVRMKRAGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKTNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKLKPLIKVIESEDYGQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLNLKDVEEGDEKFE

Source Source

Source organism organism	HOMO SAPIENS
Common name common_name	HUMAN
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	ESCHERICHIA COLI

Entity 11 Entity 11 polymer

Description description	ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1
Molecular weight formula_weight	125583.6 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K

MVLNSLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQIRGITMKSSAISLHYATGNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAERETESQVNPNSEQGEQVYDWSTGLEDTDDSHLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLMKTLWGDYYINMKAKKIMKGDQAKGKKPLFVQLILENIWSLYDAVLKKDKDKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDITAERVERLMCTGSQTFDSFPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDAKALPQNKPRPLTQEEIAQRRERARQRHAEKLAAAQGQAPLEPTQDGSAIETCPKGEEPRGDEQQVESMTPKPVLQEENNQESFIAFARVFSGVARRGKKIFVLGPKYSPLEFLRRVPLGFSAPPDGLPQVPHMAYCALENLYLLMGRELEYLEEVPPGNVLGIGGLQDFVLKSATLCSLPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLKERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQMKEDQSKIPEGIQVDSDGLITITTPNKLATLSVRAMPLPEEVTQILEENSDLIRSMEQLTSSLNEGENTHMIHQKTQEKIWEFKGKLEQHLTGRRWRNIVDQIWSFGPRKCGPNILVNKSEDFQNSVWTGPADKASKEASRYRDLGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWDLSKFEEQGASDLAKEGQEENETCSGGNENQELQDGCSEAFEKRTSQKGESPLTDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK

Source Source

Source organism organism	HOMO SAPIENS
Common name common_name	HUMAN
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	SACCHAROMYCES CEREVISIAE

Entity 12 Entity 12 polymer

Description description	26S RIBOSOMAL RNA
Molecular weight formula_weight	1205997.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	N

UCCGCCUCACCUUUGUAAGAUUACCCGCUGAACUUAAGCAUAUCAGUAAGCGGAGGAAAAGAAACUAACUAGGAUUCCGUCAGUAACGGCGAGUGAAGACGGAAUAGCCCAAGGUUCAAACCUGGAUCUCUUCGAGGUUAGGUGAUGUGACCUAUGGACUGAUGGAGCCCGCUGUUGUGACUGCUAAUUCCGUUUGGAAUUUCGAGUCGUAGAAGGUGAUAACCCUGUUCGCAGUAUCACAACAGUUGGACUUUGCCAUUAGCUCCACGAGUAGGAAUGUCUGAAAUUGCAUUCUGAAUGGGUGAUAAGAUUCAUCCAAGGCUAAAUAUAUGUUAGGAGAUCGAUAGCAUACAAGUACCGUGAGGGAAAGGUGAAAAGAACUUUGAAAAAAGGUUUAAAAGUAUUUGACACCGUUUAUGUGGAAGCGUUUACUUGGACCCCGAUUAAUGACGUCGGUUUAGCUCUAAUUCUUAGGUGGCCAAAGUAGAGUGUUACGUGCUGAUCAAAAGGUAACGGACAUUUGAUUCAUUGGUUAUCGACGAGGAAGGUACUCUAAAUCGGCCAGUUACUAACGGGUGAGAUCUGAUGUUUAUAAAAUGGGGGAUGAGGCUUAUCGGCUUGCUGGUGGCUCGCUCUCAAUAAUGGAUAUUGGGUUUCAUCAAGAGUGCAAAAUGGUGGCAAUUCACUAUUAGUGGUUAUUAAUUUUGUUUGCGUGGCUUGGCCUUGUCUACAGGUUAUCUUCGGAUGGCUUGUAGCUUUGUUGAACGCGUGGGCUUAAUGUUGUGAUUCUAGUAGCGUUACCAUAUCGUUAGAGUGGGUUCAAUAAAUGUCCCGUCUUGAAACACGGAUCAAGGAGGCCGUUUUGUGUGCGAGUGUAAGAGUAAUUAAAACUCUGACGCGUAUUGAAAGAAAGAAUACUCCAAAAGAUCGUAACUACGGUUACCUUCUGUAAGGAGUGCCCGAAUCAUGAGAACUCUGUUUCGAAAGGAUUUGCGGUUGAGCACCUAGAAUGGGACCCGAAAGGUUGUGAACUAUGCCUGAGGAAGGCGAAGUCAGGGGAAACUCUGAUGGAGGCUUGUCGCAAUGCUGACGUGCAAAUCGCUUGUCUAACUUGGGUAUAGGGGCGAAAGACUAAUCGAACAACCUAGUAGCUGGUUCCUUCCGAAGUUUCCCUCAGGAUAGCUGGAGCAGUAUUCUAGUUCCAUCUUGUAAAGACAAUGAUUAGCAGUUUCGGGGGCGUAAUGCUCUCAGCUGAUUCUCAAACUCUGAACGGGUGGGUAUCAUUUUAAUUCACUUAAUUGGAUUUUAAAAUUAAAUUGCACAUGUGCAAUGAAAAAUAGGAGCUCUUAGUGGGCCAUUUUUGGUAAGCAGAACUGGCGAUGUGGGUUGAACCAAAUAUUGGGAUAAGACGUCUAACAUUCACUAAUAGAUACCACAAAAGGUGUUAGUUCAUUAAGACAGCAGGACGGUGGCCAUGGAAGUCGGUAUCCGCUAAGGAGUGUGUAACAACUCACCUGCCAAAUGGACUAGCCCUGAAAAUGGAUGACGCUAGCAGUGGAUGGUCGAUGCCCAAUCGUUAAAAGAAGUGAUAAUACUUUUAACGUGUAGGAAGGCGUGAAGGUAACGUAGAAGCUUGAAUGUGAAUUCGAGUGGAGUUGUCUUUAGUGCAGAUCUUGAUGGUAGUAGCAAAUAUUCAAAAGAAUUUACUUUGAAGGCCGAAGUGGGGAAGGGUUCCAUAACAAUGGAAUUCACUUAUGGGUGAGUCGAUCCUAAGGUUUGGGUUAACUCUCUCUAAUAAGGUUACUAGGUCAUUGGAUCGAAAGUGAAGGUGGCUUUAACACUAGUGACUUUAUAGGCCGAAAGGGAAGCGGGUUAAAAUUCCUGCACCAUCGAAUGGGAUAUUAGGGUAACCGAUCGUAAUCCGGGACAUCAAUUGGCGGUCGAGGAAGAGUUAUCUUUUCUUGUUAACAUUGUCUUGGGGUCCUCCGAAUCAGGUCAACUGGAGACGAGGAUUCAUCGCACAAUGGAAGAGCACAGUCCUUUGGAUUGGGUCUCGCAUCCGCUAAAUGGUCCUUGAAAACCGGAUUAUGGUAUUUAAUCCUAUUUGGUGUUCGUACCAAUAACCACAUCAGGUCUCCAAGGUGAAUAGCCUCUGGUCAAAUGUAUUAAUGUAGAUAAGGGAAGUCGGCAAAACCGAUCUGUAACUUCGGGAUAAGGAUUGGCUCUAAAGGCUGGUGGAGUGGACAUAUUGGAGUUUGCUAUUUGUUUUUUACUUUUAGGAUGGGCAACUGUUUUGAAGGUUUAAGAUGGGUGGUAAUUCUUUCCAAUGUGAGGGCUUGCUCGUUCUGCUUUACGAUUAACAGCUAAUUUAGAACUGUGACGAUCACCGGGAAUCCAACUGUUUAAUUAAAACAAAGCAUUGCGAUAAGCUUAAAAGCUUUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAGAUUCAACCUAGCACGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUCAAUGAGAUUCCCACUGUCCCUAACUACUAUACAGCGAAACCACUGCAAGGGGAACGGGCCUUGCAAAAACAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUCUGAUAUUGCAUAGUGACCUAAAAGGUGUAGAAUAGGUGGGAGGGGCAACCCGACGGUGAAAUACCACCCCUUUUGGCGUUACUUUGCUAACUUGGAAUAACAGUACCUCAUAAUUCAUUUUAUGAUGGUUUUGGUGAAUAAGCGGAUCAACCACGGGUGAAAUCUGUGCAAAUUGGGCAACUGAUUUGUAUAGCAAAGUAGUCCCUCUGGUCCCGUAUUAUGUCGACCAAGAACAGUUUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUUUGUUAAAAGAUAACGCAAGUGUCCAAAGGCAGGCUCAGUGAGAACAGAAAUCUCACGUAGAGUAAAAGGGCAAAAGCCUGCUUGAUUCUGAUUUUCAGUACUAAUCGGAACUGGGAAACCAGGGCCUAUCGAUCCUUUAUGUGCUUAAAUCUUAACCCUAGAGGUGUCAGAAAAGUUACCACAGGGAUAACUGGCUUGUGGCAGCCAAGCGCUCAUAGCGACGCUGCUUUUUGAUCCUUCGAUGUCGGCUCUUCUUAUCAUUGUGAAGCAGAAUUCACAAAGUGUUGGAUUGUUCACCCACUAACAAGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGUUGUCAAUUGUUUGCGUAAUAGUAGCAUGAUUUAGUACGAGAGGAACUGUCAUGCCGGAUCACUGGUCUGUAGGUUUAUUUGACAAAAUAGUGACCUGCCGCUACCAUCCGUUGGAUAAUGGCUGAACGCCUCUAAGUCAGAAUCCAUUCUAGAAACGCAAACCAAAUGCUUUAGAGUGUGAAUGUUGUAGGUAACAUUAGGUUGUUGGUGGGGGACCACUUUCAACUUUAAACCAUAUGAUUAAUCGCUGUUACACUGCAGUUUCCUUCCGGUUAUUGUGGUGGGUGGCUAAAUUCUAAUUUAUAUCCUCGUUCCGCUCAACUCUUCGAUUGUAGACGACUAUCAAAUGAACUAGGUGCUGUAAGCUUCCGAGUAGCGUUCAGUUACGAGGGGUUGAGGCUUUUCCAUUAGUUCUUU

▶

Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	1

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	4.100 Å
Low-resolution limit resolution_low	— Å
R factor r_factor	—
R_work r_work	—
R_free r_free	—

Resolution resolution	4.10 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	11970

Mechanism of eIF6 release from the nascent 60S ribosomal subunit

1. Protein Identity and Related Structures Protein Identity & Related Structures

60S RIBOSOMAL PROTEIN L3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S RIBOSOMAL PROTEIN L9

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S ACIDIC RIBOSOMAL PROTEIN P0

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S RIBOSOMAL PROTEIN L12

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S RIBOSOMAL PROTEIN L23

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S RIBOSOMAL PROTEIN L10

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S RIBOSOMAL PROTEIN L24

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

UBIQUITIN-60S RIBOSOMAL PROTEIN L40

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

EUKARYOTIC TRANSLATION INITIATION FACTOR 6

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

RIBOSOME MATURATION PROTEIN SBDS

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer