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5b6b

Complex of LATS1 and phosphomimetic MOB1b

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

MOB kinase activator 1B

Mus musculus

UniProt Q8BPB0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Serine/threonine-protein kinase LATS1 × 2 （Q8BYR2） CHLORIDE ION × 2 ZINC ION × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 4 Serine/threonine-protein kinase LATS1 × 2 （Q8BYR2） CHLORIDE ION × 2 ZINC ION × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 4 Serine/threonine-protein kinase LATS1 × 2 （Q8BYR2） CHLORIDE ION × 2 ZINC ION × 2 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 4 Serine/threonine-protein kinase LATS1 × 2 （Q8BYR2） CHLORIDE ION × 1 ZINC ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
5b5v

1 assemblies

Homotetramer
5b5v

1 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
5b5w 5b6b 5b6b 5b6b 5b6b

5 assemblies

View Construct and Data Evidence
UniProt name MOB1B_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 3–218； UniProt 1–216 Author chain B； PDBConstruct 3–218； UniProt 1–216 Author chain D； PDBConstruct 3–218； UniProt 1–216 Author chain F； PDBConstruct 3–218； UniProt 1–216 Author chain H； PDBConstruct 3–218； UniProt 1–216 Author chain K； PDBConstruct 3–218； UniProt 1–216 Author chain M； PDBConstruct 3–218； UniProt 1–216 Author chain O； PDBConstruct 3–218； UniProt 1–216

Serine/threonine-protein kinase LATS1

Mus musculus

UniProt Q8BYR2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 MOB kinase activator 1B × 2 （Q8BPB0） CHLORIDE ION × 2 ZINC ION × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 4 MOB kinase activator 1B × 2 （Q8BPB0） CHLORIDE ION × 2 ZINC ION × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 4 MOB kinase activator 1B × 2 （Q8BPB0） CHLORIDE ION × 2 ZINC ION × 2 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 4 MOB kinase activator 1B × 2 （Q8BPB0） CHLORIDE ION × 1 ZINC ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
5b6b 5b6b 5b6b 5b6b 6j68 6j68

6 assemblies

View Construct and Data Evidence
UniProt name LATS1_MOUSE
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C； PDBConstruct 3–85； UniProt 621–703 Author chain E； PDBConstruct 3–85； UniProt 621–703 Author chain G； PDBConstruct 3–85； UniProt 621–703 Author chain I； PDBConstruct 3–85； UniProt 621–703 Author chain J； PDBConstruct 3–85； UniProt 621–703 Author chain L； PDBConstruct 3–85； UniProt 621–703 Author chain N； PDBConstruct 3–85； UniProt 621–703 Author chain P； PDBConstruct 3–85； UniProt 621–703

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5b6b
Deposition date deposition_date2016-05-26
Structure title titleComplex of LATS1 and phosphomimetic MOB1b
Keywords keywordsMOB1 LATS1 Hippo pathway, METAL BINDING PROTEIN-SIGNALING PROTEIN complex; METAL BINDING PROTEIN/SIGNALING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5b6b__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5b6b__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5b6b__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）28.66 Å
Rg (electron density)28.04 Å
Total Rg28.72 Å
Atom count4259
Residues513
Excluded volume76008 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5b6b__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 5b6b__assembly_2__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 5b6b__assembly_3__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 5b6b__assembly_4__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 8 domains

CATH v4.4 (8 domains)

Domain ID domain_id5b6bA00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology140 — Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homologous superfamily homologous superfamily30 — MOB kinase activator
Domain ID domain_id5b6bB00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology140 — Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homologous superfamily homologous superfamily30 — MOB kinase activator
Domain ID domain_id5b6bD00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology140 — Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homologous superfamily homologous superfamily30 — MOB kinase activator
Domain ID domain_id5b6bF00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology140 — Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homologous superfamily homologous superfamily30 — MOB kinase activator
Domain ID domain_id5b6bH00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology140 — Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homologous superfamily homologous superfamily30 — MOB kinase activator
Domain ID domain_id5b6bK00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology140 — Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homologous superfamily homologous superfamily30 — MOB kinase activator
Domain ID domain_id5b6bM00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology140 — Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homologous superfamily homologous superfamily30 — MOB kinase activator
Domain ID domain_id5b6bO00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology140 — Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homologous superfamily homologous superfamily30 — MOB kinase activator
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7. Citations (1)