Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | water × 2 | 与蛋白数一致 |
| UniProt名称 | HGF_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–183； UniProt 28–210 作者链 B； PDB构建体 1–183； UniProt 28–210 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 5cs1 |
| 沉积日期 deposition_date | 2015-07-23 |
| 结构标题 title | The structure of the NK1 fragment of HGF/SF |
| 关键词 keywords | HGF/SF, NK1 fragment, fragment based drug discovery, growth factor, cell cycle, hormone, new chemical entity; HORMONE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 21.65 Å |
| Rg（电子密度） | 20.95 Å |
| 总 Rg | 21.74 Å |
| 原子数 | 2752 |
| 残基数 | 346 |
| 排除体积 | 48851 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d5cs1a1 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.10 — Hairpin loop containing domain-like |
| 超家族 Superfamily superfamily | g.10.1 — Hairpin loop containing domain-like |
| 家族 Family family | g.10.1.1 — Hairpin loop containing domain |
| 结构域编号 domain_id | d5cs1a2 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.14 — Kringle-like |
| 超家族 Superfamily superfamily | g.14.1 — Kringle-like |
| 家族 Family family | g.14.1.1 — Kringle modules |
| 结构域编号 domain_id | d5cs1b1 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.10 — Hairpin loop containing domain-like |
| 超家族 Superfamily superfamily | g.10.1 — Hairpin loop containing domain-like |
| 家族 Family family | g.10.1.1 — Hairpin loop containing domain |
| 结构域编号 domain_id | d5cs1b2 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.14 — Kringle-like |
| 超家族 Superfamily superfamily | g.14.1 — Kringle-like |
| 家族 Family family | g.14.1.1 — Kringle modules |
| 结构域编号 domain_id | 5cs1A01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 50 — 3-Layer(bba) Sandwich |
| 拓扑 Topology topology | 4 — Hepatocyte Growth Factor |
| 同源超家族 H-superfamily homologous superfamily | 10 — Hepatocyte Growth Factor |
| 结构域编号 domain_id | 5cs1A02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 20 — Plasminogen Kringle 4 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Plasminogen Kringle 4 |
| 结构域编号 domain_id | 5cs1B01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 50 — 3-Layer(bba) Sandwich |
| 拓扑 Topology topology | 4 — Hepatocyte Growth Factor |
| 同源超家族 H-superfamily homologous superfamily | 10 — Hepatocyte Growth Factor |
| 结构域编号 domain_id | 5cs1B02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 20 — Plasminogen Kringle 4 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Plasminogen Kringle 4 |