SAXSdb — 5ftu

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1. Protein Identity and Related Structures Protein Identity & Related Structures

NETRIN RECEPTOR UNC5D

RATTUS NORVEGICUS

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 4	LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 × 1 （Q8BLU0） ADHESION G PROTEIN-COUPLED RECEPTOR L3 × 2 （Q80TS3） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 SODIUM ION × 2 CALCIUM ION × 2	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 4	LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 × 1 （Q8BLU0） ADHESION G PROTEIN-COUPLED RECEPTOR L3 × 2 （Q80TS3） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 SODIUM ION × 2 CALCIUM ION × 2	Consistent with protein count
3	Protein heterocomplex	Heteromer	Protein 4	LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 × 1 （Q8BLU0） ADHESION G PROTEIN-COUPLED RECEPTOR L3 × 2 （Q80TS3） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 SODIUM ION × 2 CALCIUM ION × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	UNC5D_RAT
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–130； UniProt 32–161 Author chain E； PDBConstruct 1–130； UniProt 32–161 Author chain I； PDBConstruct 1–130； UniProt 32–161

LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2

MUS MUSCULUS

UniProt Q8BLU0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 4	NETRIN RECEPTOR UNC5D × 1 （F1LW30） ADHESION G PROTEIN-COUPLED RECEPTOR L3 × 2 （Q80TS3） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 SODIUM ION × 2 CALCIUM ION × 2	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 4	NETRIN RECEPTOR UNC5D × 1 （F1LW30） ADHESION G PROTEIN-COUPLED RECEPTOR L3 × 2 （Q80TS3） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 SODIUM ION × 2 CALCIUM ION × 2	Consistent with protein count
3	Protein heterocomplex	Heteromer	Protein 4	NETRIN RECEPTOR UNC5D × 1 （F1LW30） ADHESION G PROTEIN-COUPLED RECEPTOR L3 × 2 （Q80TS3） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 SODIUM ION × 2 CALCIUM ION × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	FLRT2_MOUSE
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 3–330； UniProt 35–362 Author chain F； PDBConstruct 3–330； UniProt 35–362 Author chain J； PDBConstruct 3–330； UniProt 35–362

ADHESION G PROTEIN-COUPLED RECEPTOR L3

MUS MUSCULUS

UniProt Q80TS3

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 4	NETRIN RECEPTOR UNC5D × 1 （F1LW30） LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 × 1 （Q8BLU0） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 SODIUM ION × 2 CALCIUM ION × 2	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 4	NETRIN RECEPTOR UNC5D × 1 （F1LW30） LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 × 1 （Q8BLU0） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 SODIUM ION × 2 CALCIUM ION × 2	Consistent with protein count
3	Protein heterocomplex	Heteromer	Protein 4	NETRIN RECEPTOR UNC5D × 1 （F1LW30） LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 × 1 （Q8BLU0） 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 SODIUM ION × 2 CALCIUM ION × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	AGRL3_MOUSE
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain C； PDBConstruct 3–374； UniProt 92–463 Author chain D； PDBConstruct 3–374； UniProt 92–463 Author chain G； PDBConstruct 3–374； UniProt 92–463 Author chain H； PDBConstruct 3–374； UniProt 92–463 Author chain K； PDBConstruct 3–374； UniProt 92–463 Author chain L； PDBConstruct 3–374； UniProt 92–463

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	5ftu
Deposition date deposition_date	2016-01-15
Structure title title	Tetrameric complex of Latrophilin 3, Unc5D and FLRT2
Keywords keywords	;SIGNALING PROTEIN, SIGNALLING PROTEIN, LEUCINE-RICH REPEAT, LRR, UNC5, APOPTOSIS, UNCOORDINATED-5, NETRIN RECEPTOR, FLRT, LATROPHILIN, ADHESION, REPULSION, GUIDANCE, BETA PROPELLOR, IMMUNOGLOBULIN, THROMBOSPONDIN, OLFACTOMEDIN, LECTIN, TETRAMER ;; SIGNALING PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5ftu__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5ftu__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

5ftu__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	32.57 Å
Rg (electron density)	31.70 Å
Total Rg	32.55 Å
Atom count	8560
Residues	1060
Excluded volume	151510 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`5ftu__assembly_1__model_1`	tetrameric （4）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`5ftu__assembly_2__model_1`	tetrameric （4）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`5ftu__assembly_3__model_1`	tetrameric （4）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

Entity 1 Entity 1 polymer

Description description	NETRIN RECEPTOR UNC5D
Molecular weight formula_weight	15923.8 kDa
Source method src_method	man
Copy count entity_count	3

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,E,I
Atom count atom_count	25680

RGADSGEVLPDSIPSAPGTLPHFIEEPEDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEESLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQGTKHHHHHH

Source Source

Source organism organism	RATTUS NORVEGICUS
Common name common_name	NORWAY RAT
NCBI taxonomy ID ncbi_taxonomy_id	10116
Host organism host_organism	HOMO SAPIENS

Entity 2 Entity 2 polymer

Description description	LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2
Molecular weight formula_weight	38411.9 kDa
Source method src_method	man
Copy count entity_count	3

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B,F,J

TGACPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTRTKHHHHHH

Source Source

Source organism organism	MUS MUSCULUS
Common name common_name	HOUSE MOUSE
NCBI taxonomy ID ncbi_taxonomy_id	10090
Host organism host_organism	HOMO SAPIENS

Entity 3 Entity 3 polymer

Description description	ADHESION G PROTEIN-COUPLED RECEPTOR L3
Molecular weight formula_weight	43908.0 kDa
Source method src_method	man
Copy count entity_count	6

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C,D,G,H,K,L

TGPIPMAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYKVEQKVFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDGTKHHHHHH

Source Source

Source organism organism	MUS MUSCULUS
Common name common_name	HOUSE MOUSE
NCBI taxonomy ID ncbi_taxonomy_id	10090
Host organism host_organism	HOMO SAPIENS

Entity 4 Entity 4 non-polymer

Description description	2-acetamido-2-deoxy-beta-D-glucopyranose
Molecular weight formula_weight	221.2 kDa
Source method src_method	man
Copy count entity_count	9

Entity 5 Entity 5 non-polymer

Description description	SODIUM ION
Molecular weight formula_weight	23.0 kDa
Source method src_method	syn
Copy count entity_count	6

Entity 6 Entity 6 non-polymer

Description description	CALCIUM ION
Molecular weight formula_weight	40.1 kDa
Source method src_method	syn
Copy count entity_count	6

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Unit-cell length a length_a	292.360 Å
Unit-cell length b length_b	292.360 Å
Unit-cell length c length_c	291.770 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	96

Space group space_group	I 41 2 2
Space-group number int_tables_number	98
Crystal system crystal_system	—

Resolution resolution	6.010 Å
Low-resolution limit resolution_low	206.730 Å
R factor r_factor	0.2758
R_work r_work	0.2757
R_free r_free	0.2779

Tetrameric complex of Latrophilin 3, Unc5D and FLRT2

1. Protein Identity and Related Structures Protein Identity & Related Structures

NETRIN RECEPTOR UNC5D

State in the Current Structure

Other States of the Same Protein in the Database

LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2

State in the Current Structure

Other States of the Same Protein in the Database

ADHESION G PROTEIN-COUPLED RECEPTOR L3

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

5ftu__assembly_1__model_1

5ftu__assembly_1__model_1 | I(q)

5ftu__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (6)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 polymer

Polymer Polymer

Source Source

Entity 4 Entity 4 non-polymer

Entity 5 Entity 5 non-polymer

Entity 6 Entity 6 non-polymer

7. Citations (1)

Tetrameric complex of Latrophilin 3, Unc5D and FLRT2

1. Protein Identity and Related Structures Protein Identity & Related Structures

NETRIN RECEPTOR UNC5D

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

ADHESION G PROTEIN-COUPLED RECEPTOR L3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

5ftu__assembly_1__model_1

5ftu__assembly_1__model_1 | I(q)

5ftu__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (6)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 polymer

Polymer Polymer

Source Source

Entity 4 Entity 4 non-polymer

Entity 5 Entity 5 non-polymer

Entity 6 Entity 6 non-polymer

7. Citations (1)