SAXSdb — 6ajj

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Drug exporters of the RND superfamily-like protein,Endolysin

Enterobacteria phage T4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Monomer	Protein 1	(CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID × 2 alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside × 5 4,6-difluoro-N-(spiro[5.5]undecan-3-yl)-1H-indole-2-carboxamide × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	D9IEF7_BPT4
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 764–923； UniProt 2–161

Drug exporters of the RND superfamily-like protein,Endolysin

Enterobacteria phage T4

UniProt I7G2R2

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Monomer	Protein 1	(CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID × 2 alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside × 5 4,6-difluoro-N-(spiro[5.5]undecan-3-yl)-1H-indole-2-carboxamide × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	I7G2R2_MYCS2
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 14–761； UniProt 1–748

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	6ajj
Deposition date deposition_date	2018-08-27
Structure title title	Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with ICA38
Keywords keywords	membrane protein, transporter, RND family, cell wall biosynthesis, drug target, HYDROLASE; MEMBRANE PROTEIN, HYDROLASE
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6ajj__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6ajj__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

6ajj__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	38.53 Å
Rg (electron density)	37.95 Å
Total Rg	37.88 Å
Atom count	7181
Residues	901
Excluded volume	130110 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`6ajj__assembly_1__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Description description	Drug exporters of the RND superfamily-like protein,Endolysin
Molecular weight formula_weight	104007.6 kDa
EC 编号 ec_number	3.2.1.17
Mutation mutation	C54T, C97A
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A
Atom count atom_count	7181

MPEVVGSYFQSNAMFAWWGRTVYQFRYIVIGVMVALCLGGGVYGISLGNHVTQSGFYDEGSQSVAASLIGDEVYGRDRTSHVVAILTPPDDKKVTDKAWQKKVTEELDQVVKDHEDQIVGWVGWLKAPDTTDPTVSAMKTQDLRHTFISIPLQGDDDDEILKNYQVVEPELQQVNGGDIRLAGLNPLASELTGTIGEDQKRAEVAAIPLVAVVLFFVFGTVIAAALPAIIGGLAIAGALGIMRLVAEFTPVHFFAQPVVTLIGLGIAIDYGLFIVSRFREEIAEGYDTEAAVRRTVMTSGRTVVFSAVIIVASSVPLLLFPQGFLKSITYAIIASVMLAAILSITVLAAALAILGPRVDALGVTTLLKIPFLANWQFSRRIIDWFAEKTQKTKTREEVERGFWGRLVNVVMKRPIAFAAPILVVMVLLIIPLGQLSLGGISEKYLPPDNAVRQSQEQFDKLFPGFRTEPLTLVMKREDGEPITDAQIADMRAKALTVSGFTDPDNDPEKMWKERPANDSGSKDPSVRVIQNGLENRNDAAKKIDELRALQPPHGIEVFVGGTPALEQDSIHSLFDKLPLMALILIVTTTVLMFLAFGSVVLPIKAALMSALTLGSTMGILTWMFVDGHGSGLMNYTPQPLMAPMIGLIIAVIWGLSTDYEVFLVSRMVEARERGMSTAEAIRIGTATTGRLITGAALILAVVAGAFVFSDLVMMKYLAFGLLIALLLDATIIRMFLVPAVMKLLGDDCWWAPRWMKRVQEKEFNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYEFHLGGIKAFHHHHHHHHHH

Source Source

Source organism organism	Enterobacteria phage T4
Common name common_name	Bacteriophage T4
NCBI taxonomy ID ncbi_taxonomy_id	10665
Host organism host_organism	Mycobacterium smegmatis str. MC2 155

Entity 2 Entity 2 non-polymer

Description description	(CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID
Molecular weight formula_weight	190.2 kDa
Source method src_method	syn
Copy count entity_count	2

Entity 3 Entity 3 non-polymer

Description description	alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside
Molecular weight formula_weight	510.6 kDa
Source method src_method	syn
Copy count entity_count	5

Entity 4 Entity 4 non-polymer

Description description	4,6-difluoro-N-(spiro[5.5]undecan-3-yl)-1H-indole-2-carboxamide
Molecular weight formula_weight	346.4 kDa
Source method src_method	syn
Copy count entity_count	1

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Unit-cell length a length_a	87.386 Å
Unit-cell length b length_b	139.731 Å
Unit-cell length c length_c	140.713 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	4

Space group space_group	P 21 21 21
Space-group number int_tables_number	19
Crystal system crystal_system	—

Resolution resolution	2.794 Å
Low-resolution limit resolution_low	44.466 Å
R factor r_factor	0.2198
R_work r_work	0.2182
R_free r_free	0.2527

Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with ICA38

1. Protein Identity and Related Structures Protein Identity & Related Structures

Drug exporters of the RND superfamily-like protein,Endolysin

State in the Current Structure

Other States of the Same Protein in the Database

Drug exporters of the RND superfamily-like protein,Endolysin

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

6ajj__assembly_1__model_1

6ajj__assembly_1__model_1 | I(q)

6ajj__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

7. Citations (1)

Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with ICA38

1. Protein Identity and Related Structures Protein Identity & Related Structures

Drug exporters of the RND superfamily-like protein,Endolysin

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Drug exporters of the RND superfamily-like protein,Endolysin

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

6ajj__assembly_1__model_1

6ajj__assembly_1__model_1 | I(q)

6ajj__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

7. Citations (1)