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6b0c

KLP10A-AMPPNP in complex with curved tubulin and a microtubule

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Tubulin alpha-1B chain

OrganismNot specified

UniProt Q2XVP4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 175 Tubulin beta chain × 70 （F2Z5B2） Kinesin-like protein Klp10A × 35 （Q960Z0） GUANOSINE-5'-TRIPHOSPHATE × 70 MAGNESIUM ION × 105 GUANOSINE-5'-DIPHOSPHATE × 70 TAXOL × 35 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 35 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Tubulin beta chain × 2 （F2Z5B2） Kinesin-like protein Klp10A × 1 （Q960Z0） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 3 GUANOSINE-5'-DIPHOSPHATE × 2 TAXOL × 1 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 5 Tubulin beta chain × 2 （F2Z5B2） Kinesin-like protein Klp10A × 1 （Q960Z0） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 3 GUANOSINE-5'-DIPHOSPHATE × 2 TAXOL × 1 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3j8x 3j8y 3jak 3jal 3jar 3jas 3jat 3jaw 4zhq 4zi7 4zol 5ca0

244 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TBA1B_PIG
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–451； UniProt 1–451 Author chain C； PDBConstruct 1–451； UniProt 1–451

Tubulin beta chain

OrganismNot specified

UniProt F2Z5B2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 175 Tubulin alpha-1B chain × 70 （Q2XVP4） Kinesin-like protein Klp10A × 35 （Q960Z0） GUANOSINE-5'-TRIPHOSPHATE × 70 MAGNESIUM ION × 105 GUANOSINE-5'-DIPHOSPHATE × 70 TAXOL × 35 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 35 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Tubulin alpha-1B chain × 2 （Q2XVP4） Kinesin-like protein Klp10A × 1 （Q960Z0） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 3 GUANOSINE-5'-DIPHOSPHATE × 2 TAXOL × 1 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 5 Tubulin alpha-1B chain × 2 （Q2XVP4） Kinesin-like protein Klp10A × 1 （Q960Z0） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 3 GUANOSINE-5'-DIPHOSPHATE × 2 TAXOL × 1 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3j8x 3j8y 5ca0 5jcb 5xke 5xkh 5xp3 6b0c 6b0c 6b0c 6b0i 6b0i

16 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name F2Z5B2_PIG
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–445； UniProt 1–445 Author chain D； PDBConstruct 1–445； UniProt 1–445

Kinesin-like protein Klp10A

Drosophila melanogaster

UniProt Q960Z0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 175 Tubulin alpha-1B chain × 70 （Q2XVP4） Tubulin beta chain × 70 （F2Z5B2） GUANOSINE-5'-TRIPHOSPHATE × 70 MAGNESIUM ION × 105 GUANOSINE-5'-DIPHOSPHATE × 70 TAXOL × 35 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 35 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Tubulin alpha-1B chain × 2 （Q2XVP4） Tubulin beta chain × 2 （F2Z5B2） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 3 GUANOSINE-5'-DIPHOSPHATE × 2 TAXOL × 1 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 5 Tubulin alpha-1B chain × 2 （Q2XVP4） Tubulin beta chain × 2 （F2Z5B2） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 3 GUANOSINE-5'-DIPHOSPHATE × 2 TAXOL × 1 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3j2u 3j2u 3j2u 6b0c 6b0c 6b0c 6b0i 6b0i 6b0i 6b0l 6b0l 6b0l

12 assemblies

View Construct and Data Evidence
UniProt name KI10A_DROME
Isoform —
PDB entities 3
Chains and sequence ranges Author chain K； PDBConstruct 38–373； UniProt 279–615

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6b0c
Deposition date deposition_date2017-09-14
Structure title titleKLP10A-AMPPNP in complex with curved tubulin and a microtubule
Keywords keywordskinesin 13, microtubule, tubulin, depolymerization, MOTOR PROTEIN-STRUCTURAL PROTEIN complex; MOTOR PROTEIN/STRUCTURAL PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6b0c__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6b0c__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6b0c__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)182.90 Å
Total Rg183.00 Å
Atom count575330
Residues72450
Excluded volume10172000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6b0c__assembly_1__model_1 175-meric （175） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6b0c__assembly_2__model_1 pentameric （5） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 6b0c__assembly_3__model_1 pentameric （5） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (8)

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6. Fold Classification (SCOP + CATH) 13 domains

CATH v4.4 (13 domains)

Domain ID domain_id6b0cA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1440 — Tubulin/FtsZ, GTPase domain
Domain ID domain_id6b0cA02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
Homologous superfamily homologous superfamily20 — Tubulin/FtsZ, C-terminal domain
Domain ID domain_id6b0cA03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily600 — Helix hairpin bin
Domain ID domain_id6b0cB01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1440 — Tubulin/FtsZ, GTPase domain
Domain ID domain_id6b0cB02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
Homologous superfamily homologous superfamily20 — Tubulin/FtsZ, C-terminal domain
Domain ID domain_id6b0cB03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily600 — Helix hairpin bin
Domain ID domain_id6b0cC01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1440 — Tubulin/FtsZ, GTPase domain
Domain ID domain_id6b0cC02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
Homologous superfamily homologous superfamily20 — Tubulin/FtsZ, C-terminal domain
Domain ID domain_id6b0cC03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily600 — Helix hairpin bin
Domain ID domain_id6b0cD01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1440 — Tubulin/FtsZ, GTPase domain
Domain ID domain_id6b0cD02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
Homologous superfamily homologous superfamily20 — Tubulin/FtsZ, C-terminal domain
Domain ID domain_id6b0cD03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily600 — Helix hairpin bin
Domain ID domain_id6b0cK00
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology850 — Kinesin
Homologous superfamily homologous superfamily10 — Kinesin motor domain
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7. Citations (1)