← Back to search
6c0a

Actinin-1 EF-Hand bound to the Cav1.2 IQ Motif

Method: SOLUTION NMR
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Alpha-actinin-1

Mus musculus

UniProt Q7TPR4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Voltage-dependent L-type calcium channel subunit alpha-1C × 1 （Q13936） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6c0a

1 assemblies

View Construct and Data Evidence
UniProt name ACTN1_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–71； UniProt 822–892

Voltage-dependent L-type calcium channel subunit alpha-1C

OrganismNot specified

UniProt Q13936

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Alpha-actinin-1 × 1 （Q7TPR4） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1t0j 1t0j 2lqc 3g43 3oxq 3oxq 5v2p 5v2q 6c0a 6dad 6dad 6dae

40 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name CAC1C_HUMAN
Isoform Q13936-17
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–23； UniProt 1587–1609

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id6c0a
Deposition date deposition_date2017-12-28
Structure title titleActinin-1 EF-Hand bound to the Cav1.2 IQ Motif
Keywords keywords;actinin-1, EF hand, Calcium Calmodulin, Neuronal signaling, Voltage Gated Calcium Channel, Cav1.2, Voltage Gated Calcium Channel 1.2, Hippocampal Neurons, IQ Motif, SIGNALING PROTEIN ;; SIGNALING PROTEIN
Experimental Method methodSOLUTION NMR
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6c0a__assembly_1__model_3

Assembly 1 · Model 3 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6c0a__assembly_1__model_3 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6c0a__assembly_1__model_3 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）14.83 Å
Rg (electron density)13.53 Å
Total Rg14.71 Å
Atom count1488
Residues94
Excluded volume13445 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6c0a__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 6c0a__assembly_1__model_2 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 6c0a__assembly_1__model_3 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 6c0a__assembly_1__model_4 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (2)

▼

6. Fold Classification (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

Domain ID domain_id6c0aA00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology238 — Recoverin; domain 1
Homologous superfamily homologous superfamily10 — EF-hand
▶

7. Citations (2)