6g4w

Cryo-EM structure of a late human pre-40S ribosomal subunit - State A

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

40S ribosomal protein S17

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS17_HUMAN
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain R； PDBConstruct 1–135； UniProt 1–135

40S ribosomal protein S27

OrganismNot specified

UniProt P42677

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS27_HUMAN
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain b； PDBConstruct 1–84； UniProt 1–84

40S ribosomal protein S3a

OrganismNot specified

UniProt P61247

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS3A_HUMAN
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain B； PDBConstruct 1–264； UniProt 1–264

40S ribosomal protein S28

OrganismNot specified

UniProt P62857

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS28_HUMAN
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain c； PDBConstruct 1–69； UniProt 1–69

40S ribosomal protein S4, X isoform

OrganismNot specified

UniProt P62701

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS4X_HUMAN
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain E； PDBConstruct 1–263； UniProt 1–263

40S ribosomal protein S30

OrganismNot specified

UniProt P62861

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS30_HUMAN
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain e； PDBConstruct 1–59； UniProt 1–59

40S ribosomal protein S5

OrganismNot specified

UniProt P46782

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS5_HUMAN
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain F； PDBConstruct 1–204； UniProt 1–204

40S ribosomal protein S7

OrganismNot specified

UniProt P62081

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS7_HUMAN
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain H； PDBConstruct 1–194； UniProt 1–194

40S ribosomal protein S6

OrganismNot specified

UniProt P62753

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS6_HUMAN
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain G； PDBConstruct 1–249； UniProt 1–249

40S ribosomal protein S25

OrganismNot specified

UniProt P62851

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS25_HUMAN
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain Z； PDBConstruct 1–125； UniProt 1–125

40S ribosomal protein S24

OrganismNot specified

UniProt P62847

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS24_HUMAN
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain Y； PDBConstruct 1–133； UniProt 1–133

RNA-binding protein PNO1

OrganismNot specified

UniProt Q9NRX1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	PNO1_HUMAN
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain x； PDBConstruct 1–252； UniProt 1–252

40S ribosomal protein S23

OrganismNot specified

UniProt P62266

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS23_HUMAN
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain X； PDBConstruct 1–143； UniProt 1–143

Bystin

OrganismNot specified

UniProt Q13895

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	BYST_HUMAN
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain w； PDBConstruct 1–437； UniProt 1–437

40S ribosomal protein S15a

OrganismNot specified

UniProt P62244

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS15A_HUMAN
Isoform	—
PDB entities	16
Chains and sequence ranges	Author chain W； PDBConstruct 1–130； UniProt 1–130

Pre-rRNA-processing protein TSR1 homolog

OrganismNot specified

UniProt Q2NL82

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TSR1_HUMAN
Isoform	—
PDB entities	17
Chains and sequence ranges	Author chain u； PDBConstruct 1–804； UniProt 1–804

40S ribosomal protein S19

OrganismNot specified

UniProt P39019

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS19_HUMAN
Isoform	—
PDB entities	19
Chains and sequence ranges	Author chain T； PDBConstruct 1–145； UniProt 1–145

40S ribosomal protein S18

OrganismNot specified

UniProt P62269

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS18_HUMAN
Isoform	—
PDB entities	20
Chains and sequence ranges	Author chain S； PDBConstruct 1–152； UniProt 1–152

40S ribosomal protein S16

OrganismNot specified

UniProt P62249

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS16_HUMAN
Isoform	—
PDB entities	21
Chains and sequence ranges	Author chain Q； PDBConstruct 1–146； UniProt 1–146

40S ribosomal protein S15

OrganismNot specified

UniProt P62841

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS15_HUMAN
Isoform	—
PDB entities	22
Chains and sequence ranges	Author chain P； PDBConstruct 1–145； UniProt 1–145

40S ribosomal protein S14

OrganismNot specified

UniProt P62263

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS14_HUMAN
Isoform	—
PDB entities	23
Chains and sequence ranges	Author chain O； PDBConstruct 1–151； UniProt 1–151

40S ribosomal protein S13

OrganismNot specified

UniProt P62277

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS13_HUMAN
Isoform	—
PDB entities	24
Chains and sequence ranges	Author chain N； PDBConstruct 1–151； UniProt 1–151

40S ribosomal protein S11

OrganismNot specified

UniProt P62280

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS11_HUMAN
Isoform	—
PDB entities	25
Chains and sequence ranges	Author chain L； PDBConstruct 1–158； UniProt 1–158

40S ribosomal protein S9

OrganismNot specified

UniProt P46781

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS9_HUMAN
Isoform	—
PDB entities	26
Chains and sequence ranges	Author chain J； PDBConstruct 1–194； UniProt 1–194

40S ribosomal protein S8

OrganismNot specified

UniProt P62241

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS8_HUMAN
Isoform	—
PDB entities	27
Chains and sequence ranges	Author chain I； PDBConstruct 1–208； UniProt 1–208

Multifunctional methyltransferase subunit TRM112-like protein

OrganismNot specified

UniProt Q9UI30

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Probable 18S rRNA (guanine-N(7))-methyltransferase × 1 （O43709） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TR112_HUMAN
Isoform	—
PDB entities	29
Chains and sequence ranges	Author chain r； PDBConstruct 1–125； UniProt 1–125

Probable 18S rRNA (guanine-N(7))-methyltransferase

OrganismNot specified

UniProt O43709

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 30 RNA 1	18S ribosomal RNA × 1 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S28 × 1 （P62857） 40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S5 × 1 （P46782） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S25 × 1 （P62851） 40S ribosomal protein S24 × 1 （P62847） RNA-binding protein PNO1 × 1 （Q9NRX1） 40S ribosomal protein S23 × 1 （P62266） Bystin × 1 （Q13895） 40S ribosomal protein S15a × 1 （P62244） Pre-rRNA-processing protein TSR1 homolog × 1 （Q2NL82） UNKNOWN × 1 40S ribosomal protein S19 × 1 （P39019） 40S ribosomal protein S18 × 1 （P62269） 40S ribosomal protein S16 × 1 （P62249） 40S ribosomal protein S15 × 1 （P62841） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S8 × 1 （P62241） RRP12 × 1 Multifunctional methyltransferase subunit TRM112-like protein × 1 （Q9UI30） UNKNOWN HELIX × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	BUD23_HUMAN
Isoform	—
PDB entities	30
Chains and sequence ranges	Author chain q； PDBConstruct 1–281； UniProt 1–281

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	6g4w
Deposition date deposition_date	2018-03-28
Structure title title	Cryo-EM structure of a late human pre-40S ribosomal subunit - State A
Keywords keywords	40S, pre-40S, ribosome biogenesis, RIBOSOME; RIBOSOME
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6g4w__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6g4w__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

6g4w__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	79.58 Å
Rg (electron density)	80.57 Å
Total Rg	79.90 Å
Atom count	45223
Residues	6920
Excluded volume	722210 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`6g4w__assembly_1__model_1`	31-meric （31）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (31)

Entity 1 Entity 1 polymer

Description description	18S ribosomal RNA
Molecular weight formula_weight	607057.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	2
Atom count atom_count	45223

UACCUGGUUGAUCCUGCCAGUAGCAUAUGCUUGUCUCAAAGAUUAAGCCAUGCAUGUCUAAGUACGCACGGCCGGUACAGUGAAACUGCGAAUGGCUCAUUAAAUCAGUUAUGGUUCCUUUGGUCGCUCGCUCCUCUCCUACUUGGAUAACUGUGGUAAUUCUAGAGCUAAUACAUGCCGACGGGCGCUGACCCCCUUCGCGGGGGGGAUGCGUGCAUUUAUCAGAUCAAAACCAACCCGGUCAGCCCCUCUCCGGCCCCGGCCGGGGGGCGGGCGCCGGCGGCUUUGGUGACUCUAGAUAACCUCGGGCCGAUCGCACGCCCCCCGUGGCGGCGACGACCCAUUCGAACGUCUGCCCUAUCAACUUUCGAUGGUAGUCGCCGUGCCUACCAUGGUGACCACGGGUGACGGGGAAUCAGGGUUCGAUUCCGGAGAGGGAGCCUGAGAAACGGCUACCACAUCCAAGGAAGGCAGCAGGCGCGCAAAUUACCCACUCCCGACCCGGGGAGGUAGUGACGAAAAAUAACAAUACAGGACUCUUUCGAGGCCCUGUAAUUGGAAUGAGUCCACUUUAAAUCCUUUAACGAGGAUCCAUUGGAGGGCAAGUCUGGUGCCAGCAGCCGCGGUAAUUCCAGCUCCAAUAGCGUAUAUUAAAGUUGCUGCAGUUAAAAAGCUCGUAGUUGGAUCUUGGGAGCGGGCGGGCGGUCCGCCGCGAGGCGAGCCACCGCCCGUCCCCGCCCCUUGCCUCUCGGCGCCCCCUCGAUGCUCUUAGCUGAGUGUCCCGCGGGGCCCGAAGCGUUUACUUUGAAAAAAUUAGAGUGUUCAAAGCAGGCCCGAGCCGCCUGGAUACCGCAGCUAGGAAUAAUGGAAUAGGACCGCGGUUCUAUUUUGUUGGUUUUCGGAACUGAGGCCAUGAUUAAGAGGGACGGCCGGGGGCAUUCGUAUUGCGCCGCUAGAGGUGAAAUUCUUGGACCGGCGCAAGACGGACCAGAGCGAAAGCAUUUGCCAAGAAUGUUUUCAUUAAUCAAGAACGAAAGUCGGAGGUUCGAAGACGAUCAGAUACCGUCGUAGUUCCGACCAUAAACGAUGCCGACCGGCGAUGCGGCGGCGUUAUUCCCAUGACCCGCCGGGCAGCUUCCGGGAAACCAAAGUCUUUGGGUUCCGGGGGGAGUAUGGUUGCAAAGCUGAAACUUAAAGGAAUUGACGGAAGGGCACCACCAGGAGUGGAGCCUGCGGCUUAAUUUGACUCAACACGGGAAACCUCACCCGGCCCGGACACGGACAGGAUUGACAGAUUGAUAGCUCUUUCUCGAUUCCGUGGGUGGUGGUGCAUGGCCGUUCUUAGUUGGUGGAGCGAUUUGUCUGGUUAAUUCCGAUAACGAACGAGACUCUGGCAUGCUAACUAGUUACGCGACCCCCGAGCGGUCGGCGUCCCCCAACUUCUUAGAGGGACAAGUGGCGUUCAGCCACCCGAGAUUGAGCAAUAACAGGUCUGUGAUGCCCUUAGAUGUCCGGGGCUGCACGCGCGCUACACUGACUGGCUCAGCGUGUGCCUACCCUACGCCGGCAGGCGCGGGUAACCCGUUGAACCCCAUUCGUGAUGGGGAUCGGGGAUUGCAAUUAUUCCCCAUGAACGAGGAAUUCCCAGUAAGUGCGGGUCAUAAGCUUGCGUUGAUUAAGUCCCUGCCCUUUGUACACACCGCCCGUCGCUACUACCGAUUGGAUGGUUUAGUGAGGCCCUCGGAUCGGCCCCGCCGGGGUCGGCCCACGGCCCUGGCGGAGCGCUGAGAAGACGGUCGAACUUGACUAUCUAGAGGAAGUAAAAGUCGUAACAAGGUUUCCGUAGGUGAACCUGCGGAAGGAUCAUUAACGGAGCCCGGAG

Entity 2 Entity 2 polymer

Description description	40S ribosomal protein S17
Molecular weight formula_weight	15578.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	R

MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGPV

Entity 3 Entity 3 polymer

Description description	40S ribosomal protein S27
Molecular weight formula_weight	9480.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	b

MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH

Entity 4 Entity 4 polymer

Description description	40S ribosomal protein S3a
Molecular weight formula_weight	30002.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV

Entity 5 Entity 5 polymer

Description description	40S ribosomal protein S28
Molecular weight formula_weight	7855.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	c

MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR

Entity 6 Entity 6 polymer

Description description	40S ribosomal protein S4, X isoform
Molecular weight formula_weight	29654.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG

Entity 7 Entity 7 polymer

Description description	40S ribosomal protein S30
Molecular weight formula_weight	6668.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	e

KVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPNANS

Entity 8 Entity 8 polymer

Description description	40S ribosomal protein S5
Molecular weight formula_weight	22913.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F

MTEWETAAPAVAETPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR

Entity 9 Entity 9 polymer

Description description	40S ribosomal protein S7
Molecular weight formula_weight	22168.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

MFSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL

Entity 10 Entity 10 polymer

Description description	40S ribosomal protein S6
Molecular weight formula_weight	28751.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G

MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK

Entity 11 Entity 11 polymer

Description description	40S ribosomal protein S25
Molecular weight formula_weight	13776.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Z

MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA

Entity 12 Entity 12 polymer

Description description	40S ribosomal protein S24
Molecular weight formula_weight	15463.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Y

MNDTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAGKKPKE

Entity 13 Entity 13 polymer

Description description	RNA-binding protein PNO1
Molecular weight formula_weight	27970.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	x

MESEMETQSARAEEGFTQVTRKGGRRAKKRQAEQLSAAGEGGDAGRMDTEEARPAKRPVFPPLCGDGLLSGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKETKDVSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF

Entity 14 Entity 14 polymer

Description description	40S ribosomal protein S23
Molecular weight formula_weight	15844.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	X

MGKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS

Entity 15 Entity 15 polymer

Description description	Bystin
Molecular weight formula_weight	49673.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	w

MPKFKAARGVGGQEKHAPLADQILAGNAVRAGVREKRRGRGTGEAEEEYVGPRLSRRILQQARQQQEELEAEHGTGDKPAAPRERTTRLGPRMPQDGSDDEDEEWPTLEKAATMTAAGHHAEVVVDPEDERAIEMFMNKNPPARRTLADIIMEKLTEKQTEVETVMSEVSGFPMPQLDPRVLEVYRGVREVLSKYRSGKLPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRDDVAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDALVFHFLGFRTEKRELPVLWHQCLLTLVQRYKADLATDQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVEDVPITVE

Entity 16 Entity 16 polymer

Description description	40S ribosomal protein S15a
Molecular weight formula_weight	14865.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	W

MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF

Entity 17 Entity 17 polymer

Description description	Pre-rRNA-processing protein TSR1 homolog
Molecular weight formula_weight	91951.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	u

MAAHRPGPLKQQNKAHKGGRHRGRGSAQRDGKGRLALKTLSKKVRKELSRVDQRHRASQLRKQKKEAVLAEKRQLGGKDGPPHQVLVVPLHSRISLPEAMQLLQDRDTGTVHLNELGNTQNFMLLCPRLKHRWFFTSARPGDLHVVLDMAKVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGISGLPLKKQIDTRKKLSKAVEKRFPHDKLLLLDTQQEAGMLLRQLANQKQQHLAFRDRRAYLFAHAVDFVPSEENNLVGTLKISGYVRGQTLNVNRLLHIVGYGDFQMKQIDAPGDPFPLNPRGIKPQKDPDMAMEICATDAVDDMEEGLKVLMKADPGRQESLQAEVIPDPMEGEQTWPTEEELSEAKDFLKESSKVVKKVPKGTSSYQAEWILDGGSQSGGEGDEYEYDDMEHEDFMEEESQDESSEEEEEYETMTIGESVHDDLYDKKVDEEAEAKMLEKYKQERLEEMFPDEVDTPRDVAARIRFQKYRGLKSFRTSPWDPKENLPQDYARIFQFQNFTNTRKSIFKEVEEKEVEGAEVGWYVTLHVSEVPVSVVECFRQGTPLIAFSLLPHEQKMSVLNMVVRRDPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAADKHKLQRFLTADMALVATVYAPITFPPASVLLFKQKSNGMHSLIATGHLMSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVLWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWLKSEISSTVPQGGME

Entity 18 Entity 18 polymer

Description description	UNKNOWN
Molecular weight formula_weight	2054.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	t

SICSTASNLYNHPQLIKY

Entity 19 Entity 19 polymer

Description description	40S ribosomal protein S19
Molecular weight formula_weight	16091.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	T

MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH

Entity 20 Entity 20 polymer

Description description	40S ribosomal protein S18
Molecular weight formula_weight	17759.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	S

MSLVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVGVSKKK

Entity 21 Entity 21 polymer

Description description	40S ribosomal protein S16
Molecular weight formula_weight	16477.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Q

MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

Entity 22 Entity 22 polymer

Description description	40S ribosomal protein S15
Molecular weight formula_weight	17076.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	P

MAEVEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQHSLLKRLRKAKKEAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK

Entity 23 Entity 23 polymer

Description description	40S ribosomal protein S14
Molecular weight formula_weight	16302.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	O

MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Entity 24 Entity 24 polymer

Description description	40S ribosomal protein S13
Molecular weight formula_weight	17259.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N

MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA

Entity 25 Entity 25 polymer

Description description	40S ribosomal protein S11
Molecular weight formula_weight	18468.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L

MADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKKQFQKF

Entity 26 Entity 26 polymer

Description description	40S ribosomal protein S9
Molecular weight formula_weight	22641.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J

MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED

Entity 27 Entity 27 polymer

Description description	40S ribosomal protein S8
Molecular weight formula_weight	24263.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKGK

Entity 28 Entity 28 polymer

Description description	RRP12
Molecular weight formula_weight	68101.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	s

XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

Entity 29 Entity 29 polymer

Description description	Multifunctional methyltransferase subunit TRM112-like protein
Molecular weight formula_weight	14215.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	r

MKLLTHNLLSSHVRGVGSRGFPLRLQATEVRICPVEFNPNFVARMIPKVEWSAFLEAADNLRLIQVPKGPVEGYEENEEFLRTMHHLLLEVEVIEGTLQCPESGRMFPISRGIPNMLLSEEETES

Entity 30 Entity 30 polymer

Description description	Probable 18S rRNA (guanine-N(7))-methyltransferase
Molecular weight formula_weight	31925.4 kDa
EC 编号 ec_number	2.1.1.-
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	q

MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCISISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNERFPLRMSRRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF

Entity 31 Entity 31 polymer

Description description	UNKNOWN HELIX
Molecular weight formula_weight	1368.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	k

AAAAAAAAAAAAAAAAAAA

▶

Resolution resolution	4.50 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	52414

Cryo-EM structure of a late human pre-40S ribosomal subunit - State A

1. Protein Identity and Related Structures Protein Identity & Related Structures

40S ribosomal protein S17

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S27

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S3a

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S28

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S4, X isoform

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S30

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S5

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S7

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S6

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S25

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer