← Back to search
6hc2

Crystal structure of NuMA/LGN hetero-hexamers

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

G-protein-signaling modulator 2

Homo sapiens

UniProt P81274

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 Nuclear mitotic apparatus protein 1 × 3 （Q14980） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 Nuclear mitotic apparatus protein 1 × 3 （Q14980） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 6 Nuclear mitotic apparatus protein 1 × 3 （Q14980） Consistent with protein count
4 Protein heterocomplex Heteromer Protein 6 Nuclear mitotic apparatus protein 1 × 3 （Q14980） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3sf4 3sf4 3sf4 4wnd 4wne 4wnf 4wng 5a6c 5a6c 6hc2 6hc2 6hc2

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name GPSM2_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 7–367； UniProt 14–374 Author chain C； PDBConstruct 7–367； UniProt 14–374 Author chain E； PDBConstruct 7–367； UniProt 14–374 Author chain G； PDBConstruct 7–367； UniProt 14–374 Author chain I； PDBConstruct 7–367； UniProt 14–374 Author chain K； PDBConstruct 7–367； UniProt 14–374 Author chain M； PDBConstruct 7–367； UniProt 14–374 Author chain O； PDBConstruct 7–367； UniProt 14–374 Author chain Q； PDBConstruct 7–367； UniProt 14–374 Author chain S； PDBConstruct 7–367； UniProt 14–374 Author chain U； PDBConstruct 7–367； UniProt 14–374 Author chain W； PDBConstruct 7–367； UniProt 14–374

Nuclear mitotic apparatus protein 1

Homo sapiens

UniProt Q14980

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 G-protein-signaling modulator 2 × 3 （P81274） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 G-protein-signaling modulator 2 × 3 （P81274） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 6 G-protein-signaling modulator 2 × 3 （P81274） Consistent with protein count
4 Protein heterocomplex Heteromer Protein 6 G-protein-signaling modulator 2 × 3 （P81274） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
6qja 6qja 6qja 6qja

4 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3ro2 5gxw 6hc2 6hc2 6hc2 6hc2 9hhl

7 assemblies

View Construct and Data Evidence
UniProt name NUMA1_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 3–71； UniProt 1860–1928 Author chain D； PDBConstruct 3–71； UniProt 1860–1928 Author chain F； PDBConstruct 3–71； UniProt 1860–1928 Author chain H； PDBConstruct 3–71； UniProt 1860–1928 Author chain J； PDBConstruct 3–71； UniProt 1860–1928 Author chain L； PDBConstruct 3–71； UniProt 1860–1928 Author chain N； PDBConstruct 3–71； UniProt 1860–1928 Author chain P； PDBConstruct 3–71； UniProt 1860–1928 Author chain R； PDBConstruct 3–71； UniProt 1860–1928 Author chain T； PDBConstruct 3–71； UniProt 1860–1928 Author chain V； PDBConstruct 3–71； UniProt 1860–1928 Author chain X； PDBConstruct 3–71； UniProt 1860–1928

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id6hc2
Deposition date deposition_date2018-08-13
Structure title titleCrystal structure of NuMA/LGN hetero-hexamers
Keywords keywordsCell division Asymmetric cell division Spindle orientation Force generator, CELL CYCLE; CELL CYCLE
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6hc2__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6hc2__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6hc2__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）41.01 Å
Rg (electron density)40.55 Å
Total Rg41.04 Å
Atom count9376
Residues1216
Excluded volume164570 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6hc2__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6hc2__assembly_2__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 6hc2__assembly_3__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 6hc2__assembly_4__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (2)

▶

7. Citations (1)