6hg9

Crystal Structure of the human IL-17RC ECD in complex with human IL-17F, Crystal form II

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Interleukin-17F

Homo sapiens

UniProt Q96PD4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Interleukin-17 receptor C × 2 (Q8NAC3) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name IL17F_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 7–139; UniProt 31–163

Interleukin-17 receptor C

Homo sapiens

UniProt Q8NAC3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Interleukin-17F × 2 (Q96PD4) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name I17RC_HUMAN
Isoform Q8NAC3-2
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 1–447; UniProt 21–467

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6hg9
Deposition date deposition_date2018-08-23
Structure title titleCrystal Structure of the human IL-17RC ECD in complex with human IL-17F, Crystal form II
Keywords keywordsCystine-knot, FnIII domains, receptor-cytokine complex, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6hg9__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6hg9__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6hg9__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)42.48 Å
Rg (electron density)42.75 Å
Total Rg42.82 Å
Atom count8338
Residues1064
Excluded volume148210 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6hg9__assembly_1__model_1 tetrameric (4) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

Domain ID domain_id6hg9A01
Class class2 — Mainly Beta
Architecture architecture10 — Ribbon
Topology topology90 — Cystine Knot Cytokines, subunit B
Homologous superfamily homologous superfamily10 — Cystine-knot cytokines
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7. Citations (1)