6hvt

Yeast 20S proteasome with human beta2i (1-53) in complex with 20

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Proteasome subunit alpha type-2

物种未注明

UniProt P23639

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA2_YEAST
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–250; UniProt 1–250 作者链 O; PDB构建体 1–250; UniProt 1–250

Proteasome subunit alpha type-3

物种未注明

UniProt P23638

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA3_YEAST
Isoform —
PDB实体 2
链与序列区间 作者链 B; PDB构建体 1–258; UniProt 1–258 作者链 P; PDB构建体 1–258; UniProt 1–258

Proteasome subunit alpha type-4

物种未注明

UniProt P40303

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA4_YEAST
Isoform —
PDB实体 3
链与序列区间 作者链 C; PDB构建体 1–254; UniProt 1–254 作者链 Q; PDB构建体 1–254; UniProt 1–254

Proteasome subunit alpha type-5

物种未注明

UniProt P32379

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA5_YEAST
Isoform —
PDB实体 4
链与序列区间 作者链 D; PDB构建体 1–260; UniProt 1–260 作者链 R; PDB构建体 1–260; UniProt 1–260

Proteasome subunit alpha type-6

物种未注明

UniProt P40302

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA6_YEAST
Isoform —
PDB实体 5
链与序列区间 作者链 E; PDB构建体 1–234; UniProt 1–234 作者链 S; PDB构建体 1–234; UniProt 1–234

Probable proteasome subunit alpha type-7

物种未注明

UniProt P21242

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA7_YEAST
Isoform —
PDB实体 6
链与序列区间 作者链 F; PDB构建体 1–288; UniProt 1–288 作者链 T; PDB构建体 1–288; UniProt 1–288

Proteasome subunit alpha type-1

物种未注明

UniProt P21243

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA1_YEAST
Isoform —
PDB实体 7
链与序列区间 作者链 G; PDB构建体 1–252; UniProt 1–252 作者链 U; PDB构建体 1–252; UniProt 1–252

Proteasome subunit beta type-10,Proteasome subunit beta type-2

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt P25043

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB2_YEAST
Isoform —
PDB实体 8
链与序列区间 作者链 H; PDB构建体 54–226; UniProt 83–255 作者链 V; PDB构建体 54–226; UniProt 83–255

Proteasome subunit beta type-10,Proteasome subunit beta type-2

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt P40306

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB10_HUMAN
Isoform —
PDB实体 8
链与序列区间 作者链 H; PDB构建体 1–53; UniProt 40–92 作者链 V; PDB构建体 1–53; UniProt 40–92

Proteasome subunit beta type-3

物种未注明

UniProt P25451

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB3_YEAST
Isoform —
PDB实体 9
链与序列区间 作者链 I; PDB构建体 1–205; UniProt 1–205 作者链 W; PDB构建体 1–205; UniProt 1–205

Proteasome subunit beta type-4

物种未注明

UniProt P22141

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB4_YEAST
Isoform —
PDB实体 10
链与序列区间 作者链 J; PDB构建体 1–198; UniProt 1–198 作者链 X; PDB构建体 1–198; UniProt 1–198

Proteasome subunit beta type-5

物种未注明

UniProt P30656

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB5_YEAST
Isoform —
PDB实体 11
链与序列区间 作者链 K; PDB构建体 1–212; UniProt 76–287 作者链 Y; PDB构建体 1–212; UniProt 76–287

Proteasome subunit beta type-6

物种未注明

UniProt P23724

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB6_YEAST
Isoform —
PDB实体 12
链与序列区间 作者链 L; PDB构建体 1–222; UniProt 20–241 作者链 Z; PDB构建体 1–222; UniProt 20–241

Proteasome subunit beta type-7

物种未注明

UniProt P30657

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB7_YEAST
Isoform —
PDB实体 13
链与序列区间 作者链 M; PDB构建体 1–246; UniProt 21–266 作者链 a; PDB构建体 1–246; UniProt 21–266

Proteasome subunit beta type-1

物种未注明

UniProt P38624

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;~{N}-[(2~{S})-1-[[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-methoxy-1-oxidanylidene-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide ; × 4 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB1_YEAST
Isoform —
PDB实体 14
链与序列区间 作者链 N; PDB构建体 1–196; UniProt 20–215 作者链 b; PDB构建体 1–196; UniProt 20–215

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id6hvt
沉积日期 deposition_date2018-10-11
结构标题 titleYeast 20S proteasome with human beta2i (1-53) in complex with 20
关键词 keywordsProteasome, Mutant, Inhibitor, Binding Analysis, HYDROLASE; HYDROLASE
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

6hvt__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

6hvt__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

6hvt__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)60.23 Å
Rg(电子密度)59.77 Å
总 Rg59.97 Å
原子数49502
残基数6341
排除体积881550 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 6hvt__assembly_1__model_1 28-meric (28) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (18)

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6. 折叠分类 (SCOP + CATH) 56 domains

SCOP 2.08 (28 domains)

结构域编号 domain_idd6hvta_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtb_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtc1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtc2
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd6hvtd_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvte_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtf_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtg_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvth_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvti_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtj_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtk_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtl_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtm_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtn_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvto_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtp_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtq1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtq2
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd6hvtr_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvts_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtt_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtu_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtv_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtw_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtx_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvty_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvtz_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits

CATH v4.4 (28 domains)

结构域编号 domain_id6hvtA00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtB00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtC00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtD00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtE00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtF00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtG00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtH00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtI00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtJ00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtK00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtL00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtM00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtN00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtO00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtP00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtQ00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtR00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtS00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtT00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtU00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtV00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtW00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtX00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtY00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtZ00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvta00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvtb00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
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7. 引用文献 (1)