6hvv

Yeast 20S proteasome with human beta2i (1-53) in complex with 39

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Proteasome subunit alpha type-2

物种未注明

UniProt P23639

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA2_YEAST
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–250; UniProt 1–250 作者链 O; PDB构建体 1–250; UniProt 1–250

Proteasome subunit alpha type-3

物种未注明

UniProt P23638

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA3_YEAST
Isoform —
PDB实体 2
链与序列区间 作者链 B; PDB构建体 1–258; UniProt 1–258 作者链 P; PDB构建体 1–258; UniProt 1–258

Proteasome subunit alpha type-4

物种未注明

UniProt P40303

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA4_YEAST
Isoform —
PDB实体 3
链与序列区间 作者链 C; PDB构建体 1–254; UniProt 1–254 作者链 Q; PDB构建体 1–254; UniProt 1–254

Proteasome subunit alpha type-5

物种未注明

UniProt P32379

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA5_YEAST
Isoform —
PDB实体 4
链与序列区间 作者链 D; PDB构建体 1–260; UniProt 1–260 作者链 R; PDB构建体 1–260; UniProt 1–260

Proteasome subunit alpha type-6

物种未注明

UniProt P40302

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA6_YEAST
Isoform —
PDB实体 5
链与序列区间 作者链 E; PDB构建体 1–234; UniProt 1–234 作者链 S; PDB构建体 1–234; UniProt 1–234

Probable proteasome subunit alpha type-7

物种未注明

UniProt P21242

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA7_YEAST
Isoform —
PDB实体 6
链与序列区间 作者链 F; PDB构建体 1–288; UniProt 1–288 作者链 T; PDB构建体 1–288; UniProt 1–288

Proteasome subunit alpha type-1

物种未注明

UniProt P21243

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA1_YEAST
Isoform —
PDB实体 7
链与序列区间 作者链 G; PDB构建体 1–252; UniProt 1–252 作者链 U; PDB构建体 1–252; UniProt 1–252

Proteasome subunit beta type-10,Proteasome subunit beta type-2

Saccharomyces cerevisiae S288C

UniProt P25043

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB2_YEAST
Isoform —
PDB实体 8
链与序列区间 作者链 H; PDB构建体 54–226; UniProt 83–255 作者链 V; PDB构建体 54–226; UniProt 83–255

Proteasome subunit beta type-10,Proteasome subunit beta type-2

Saccharomyces cerevisiae S288C

UniProt P40306

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB10_HUMAN
Isoform —
PDB实体 8
链与序列区间 作者链 H; PDB构建体 1–53; UniProt 40–92 作者链 V; PDB构建体 1–53; UniProt 40–92

Proteasome subunit beta type-3

物种未注明

UniProt P25451

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB3_YEAST
Isoform —
PDB实体 9
链与序列区间 作者链 I; PDB构建体 1–205; UniProt 1–205 作者链 W; PDB构建体 1–205; UniProt 1–205

Proteasome subunit beta type-4

物种未注明

UniProt P22141

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB4_YEAST
Isoform —
PDB实体 10
链与序列区间 作者链 J; PDB构建体 1–198; UniProt 1–198 作者链 X; PDB构建体 1–198; UniProt 1–198

Proteasome subunit beta type-5

物种未注明

UniProt P30656

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB5_YEAST
Isoform —
PDB实体 11
链与序列区间 作者链 K; PDB构建体 1–212; UniProt 76–287 作者链 Y; PDB构建体 1–212; UniProt 76–287

Proteasome subunit beta type-6

物种未注明

UniProt P23724

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-7 × 2 (P30657) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB6_YEAST
Isoform —
PDB实体 12
链与序列区间 作者链 L; PDB构建体 1–222; UniProt 20–241 作者链 Z; PDB构建体 1–222; UniProt 20–241

Proteasome subunit beta type-7

物种未注明

UniProt P30657

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-1 × 2 (P38624) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB7_YEAST
Isoform —
PDB实体 13
链与序列区间 作者链 M; PDB构建体 1–246; UniProt 21–266 作者链 a; PDB构建体 1–246; UniProt 21–266

Proteasome subunit beta type-1

物种未注明

UniProt P38624

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 28 Proteasome subunit alpha type-2 × 2 (P23639) Proteasome subunit alpha type-3 × 2 (P23638) Proteasome subunit alpha type-4 × 2 (P40303) Proteasome subunit alpha type-5 × 2 (P32379) Proteasome subunit alpha type-6 × 2 (P40302) Probable proteasome subunit alpha type-7 × 2 (P21242) Proteasome subunit alpha type-1 × 2 (P21243) Proteasome subunit beta type-10,Proteasome subunit beta type-2 × 2 (P25043,P40306) Proteasome subunit beta type-3 × 2 (P25451) Proteasome subunit beta type-4 × 2 (P22141) Proteasome subunit beta type-5 × 2 (P30656) Proteasome subunit beta type-6 × 2 (P23724) Proteasome subunit beta type-7 × 2 (P30657) MAGNESIUM ION × 8 CHLORIDE ION × 2 ;(2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide ; × 4 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 water × 28 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSB1_YEAST
Isoform —
PDB实体 14
链与序列区间 作者链 N; PDB构建体 1–196; UniProt 20–215 作者链 b; PDB构建体 1–196; UniProt 20–215

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id6hvv
沉积日期 deposition_date2018-10-11
结构标题 titleYeast 20S proteasome with human beta2i (1-53) in complex with 39
关键词 keywordsProteasome, Mutant, Inhibitor, Binding Analysis, HYDROLASE; HYDROLASE
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

6hvv__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

6hvv__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

6hvv__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)60.12 Å
Rg(电子密度)59.63 Å
总 Rg59.84 Å
原子数49538
残基数6341
排除体积882410 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 6hvv__assembly_1__model_1 28-meric (28) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (19)

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6. 折叠分类 (SCOP + CATH) 56 domains

SCOP 2.08 (28 domains)

结构域编号 domain_idd6hvva_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvb_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvc1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvc2
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd6hvvd_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvve_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvf_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvg_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.0 — automated matches
结构域编号 domain_idd6hvvh_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvi_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvj_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvk_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvl_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvm_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvn_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvo_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvp_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvq1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvq2
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd6hvvr_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvs_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvt_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvu_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.0 — automated matches
结构域编号 domain_idd6hvvv_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvw_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvx_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvy_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits
结构域编号 domain_idd6hvvz_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.153 — Ntn hydrolase-like
超家族 Superfamily superfamilyd.153.1 — N-terminal nucleophile aminohydrolases (Ntn hydrolases)
家族 Family familyd.153.1.4 — Proteasome subunits

CATH v4.4 (28 domains)

结构域编号 domain_id6hvvA00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvB00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvC00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvD00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvE00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvF00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvG00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvH00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvI00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvJ00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvK00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvL00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvM00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvN00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvO00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvP00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvQ00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvR00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvS00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvT00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvU00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvV00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvW00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvX00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvY00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvZ00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvva00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
结构域编号 domain_id6hvvb00
类 Class class3 — Alpha Beta
架构 Architecture architecture60 — 4-Layer Sandwich
拓扑 Topology topology20 — Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
同源超家族 H-superfamily homologous superfamily10 — Aminohydrolase, N-terminal nucleophile (Ntn) domain
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7. 引用文献 (1)