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6s7o

Cryo-EM structure of human oligosaccharyltransferase complex OST-A

Method: ELECTRON MICROSCOPY
▼

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

物种未注明

UniProt P46977

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 8 其他聚合物 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 × 1 （P0C6T2） Transmembrane protein 258 × 1 （P61165） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 × 1 （P61803） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （P04843） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （P04844） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit × 1 （A0A024RAD5） Oligosaccharyltransferase complex subunit OSTC × 1 （Q9NRP0） beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;(2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol ; × 9 (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium × 7 MAGNESIUM ION × 2 [(3~{R},6~{Z},10~{Z},14~{Z},18~{Z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate × 1 与蛋白数一致

数据库中的同蛋白其他状态

单体

暂无

同源二聚体

暂无

同源四聚体

暂无

其他同源多聚体

暂无

异源或核酸复合物
6s7o 8b6l 8pn9 9n9j 9ygy

共 5 个 assembly

查看构建体与数据证据
UniProt名称 STT3A_HUMAN
Isoform —
PDB实体 1
链与序列区间 作者链 A； PDB构建体 1–705； UniProt 1–705

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

物种未注明

UniProt P0C6T2

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 8 其他聚合物 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A × 1 （P46977） Transmembrane protein 258 × 1 （P61165） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 × 1 （P61803） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （P04843） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （P04844） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit × 1 （A0A024RAD5） Oligosaccharyltransferase complex subunit OSTC × 1 （Q9NRP0） beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;(2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol ; × 9 (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium × 7 MAGNESIUM ION × 2 [(3~{R},6~{Z},10~{Z},14~{Z},18~{Z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate × 1 与蛋白数一致

数据库中的同蛋白其他状态

单体
2lat

共 1 个 assembly

同源二聚体

暂无

同源四聚体

暂无

其他同源多聚体

暂无

异源或核酸复合物
6s7o 6s7t 8b6l 8pn9 9n9j 9ygy

共 6 个 assembly

查看构建体与数据证据
UniProt名称 OST4_HUMAN
Isoform —
PDB实体 2
链与序列区间 作者链 B； PDB构建体 1–37； UniProt 1–37

Transmembrane protein 258

物种未注明

UniProt P61165

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 8 其他聚合物 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A × 1 （P46977） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 × 1 （P0C6T2） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 × 1 （P61803） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （P04843） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （P04844） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit × 1 （A0A024RAD5） Oligosaccharyltransferase complex subunit OSTC × 1 （Q9NRP0） beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;(2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol ; × 9 (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium × 7 MAGNESIUM ION × 2 [(3~{R},6~{Z},10~{Z},14~{Z},18~{Z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate × 1 与蛋白数一致

数据库中的同蛋白其他状态

单体

暂无

同源二聚体

暂无

同源四聚体

暂无

其他同源多聚体

暂无

异源或核酸复合物
6s7o 6s7t 8b6l 8pn9 9n9j 9ygy

共 6 个 assembly

查看构建体与数据证据
UniProt名称 TM258_HUMAN
Isoform —
PDB实体 3
链与序列区间 作者链 C； PDB构建体 1–79； UniProt 1–79

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

物种未注明

UniProt P61803

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 8 其他聚合物 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A × 1 （P46977） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 × 1 （P0C6T2） Transmembrane protein 258 × 1 （P61165） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （P04843） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （P04844） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit × 1 （A0A024RAD5） Oligosaccharyltransferase complex subunit OSTC × 1 （Q9NRP0） beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;(2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol ; × 9 (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium × 7 MAGNESIUM ION × 2 [(3~{R},6~{Z},10~{Z},14~{Z},18~{Z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate × 1 与蛋白数一致

数据库中的同蛋白其他状态

单体

暂无

同源二聚体

暂无

同源四聚体

暂无

其他同源多聚体

暂无

异源或核酸复合物
6s7o 6s7t 8b6l 8pn9 9n9j 9ygy

共 6 个 assembly

查看构建体与数据证据
UniProt名称 DAD1_HUMAN
Isoform —
PDB实体 4
链与序列区间 作者链 D； PDB构建体 1–113； UniProt 1–113

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

物种未注明

UniProt P04843

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 8 其他聚合物 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A × 1 （P46977） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 × 1 （P0C6T2） Transmembrane protein 258 × 1 （P61165） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 × 1 （P61803） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （P04844） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit × 1 （A0A024RAD5） Oligosaccharyltransferase complex subunit OSTC × 1 （Q9NRP0） beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;(2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol ; × 9 (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium × 7 MAGNESIUM ION × 2 [(3~{R},6~{Z},10~{Z},14~{Z},18~{Z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate × 1 与蛋白数一致

数据库中的同蛋白其他状态

单体

暂无

同源二聚体

暂无

同源四聚体

暂无

其他同源多聚体

暂无

异源或核酸复合物
6s7o 6s7t 8b6l 8pn9 9n9j 9ygy

共 6 个 assembly

查看构建体与数据证据
UniProt名称 RPN1_HUMAN
Isoform —
PDB实体 5
链与序列区间 作者链 E； PDB构建体 1–607； UniProt 1–607

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

物种未注明

UniProt P04844

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 8 其他聚合物 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A × 1 （P46977） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 × 1 （P0C6T2） Transmembrane protein 258 × 1 （P61165） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 × 1 （P61803） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （P04843） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit × 1 （A0A024RAD5） Oligosaccharyltransferase complex subunit OSTC × 1 （Q9NRP0） beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;(2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol ; × 9 (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium × 7 MAGNESIUM ION × 2 [(3~{R},6~{Z},10~{Z},14~{Z},18~{Z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate × 1 与蛋白数一致

数据库中的同蛋白其他状态

单体

暂无

同源二聚体

暂无

同源四聚体

暂无

其他同源多聚体

暂无

异源或核酸复合物
6s7o 6s7t 8b6l 8pn9 9n9j 9ygy

共 6 个 assembly

查看构建体与数据证据
UniProt名称 RPN2_HUMAN
Isoform —
PDB实体 6
链与序列区间 作者链 F； PDB构建体 1–631； UniProt 1–631

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

物种未注明

UniProt A0A024RAD5

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 8 其他聚合物 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A × 1 （P46977） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 × 1 （P0C6T2） Transmembrane protein 258 × 1 （P61165） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 × 1 （P61803） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （P04843） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （P04844） Oligosaccharyltransferase complex subunit OSTC × 1 （Q9NRP0） beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;(2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol ; × 9 (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium × 7 MAGNESIUM ION × 2 [(3~{R},6~{Z},10~{Z},14~{Z},18~{Z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate × 1 与蛋白数一致

数据库中的同蛋白其他状态

单体

暂无

同源二聚体

暂无

同源四聚体

暂无

其他同源多聚体

暂无

异源或核酸复合物
6s7o 6s7t

共 2 个 assembly

查看构建体与数据证据
UniProt名称 A0A024RAD5_HUMAN
Isoform —
PDB实体 7
链与序列区间 作者链 G； PDB构建体 1–456； UniProt 1–456

Oligosaccharyltransferase complex subunit OSTC

Homo sapiens

UniProt Q9NRP0

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 8 其他聚合物 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A × 1 （P46977） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 × 1 （P0C6T2） Transmembrane protein 258 × 1 （P61165） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 × 1 （P61803） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （P04843） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （P04844） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit × 1 （A0A024RAD5） beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;(2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol ; × 9 (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium × 7 MAGNESIUM ION × 2 [(3~{R},6~{Z},10~{Z},14~{Z},18~{Z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate × 1 与蛋白数一致

数据库中的同蛋白其他状态

单体

暂无

同源二聚体

暂无

同源四聚体

暂无

其他同源多聚体

暂无

异源或核酸复合物
6s7o 8b6l 8pn9 9n9j 9ygy

共 5 个 assembly

查看构建体与数据证据
UniProt名称 OSTC_HUMAN
Isoform —
PDB实体 8
链与序列区间 作者链 H； PDB构建体 1–149； UniProt 1–149

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id6s7o
沉积日期 deposition_date2019-07-05
结构标题 titleCryo-EM structure of human oligosaccharyltransferase complex OST-A
关键词 keywordsN-glycosylation, Oligosaccharyltransferase, OSTA, TRANSFERASE; TRANSFERASE
实验方法 methodELECTRON MICROSCOPY
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

6s7o__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

6s7o__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点；横轴和纵轴均采用对数尺度。

6s7o__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置，不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg（Guinier）49.04 Å
Rg（电子密度）48.52 Å
总 Rg48.51 Å
原子数18118
残基数2197
排除体积328810 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 6s7o__assembly_1__model_1 octameric （8） 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (15)

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7. 引用文献 (1)