← Back to search
6wav

Crystal structure of PHF1 in complex with H3K36me3 substitution

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

PHD finger protein 1

Homo sapiens

UniProt O43189

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Histone H3.1 × 1 （P68431） SULFATE ION × 1 UNKNOWN ATOM OR ION × 17 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Histone H3.1 × 1 （P68431） UNKNOWN ATOM OR ION × 11 water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 2 Histone H3.1 × 1 （P68431） UNKNOWN ATOM OR ION × 8 water × 2 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 2 Histone H3.1 × 1 （P68431） UNKNOWN ATOM OR ION × 8 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2e5p 5xfn 5xfo 5xfp 5xfp

5 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2m0o 4hcz 4hcz 5xfp 6wat 6wat 6wat 6wat 6wat 6wat 6wat 6wat

31 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PHF1_HUMAN
Isoform O43189-2
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–61； UniProt 28–87 Author chain B； PDBConstruct 2–61； UniProt 28–87 Author chain C； PDBConstruct 2–61； UniProt 28–87 Author chain D； PDBConstruct 2–61； UniProt 28–87

Histone H3.1

OrganismNot specified

UniProt P68431

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 PHD finger protein 1 × 1 （O43189） SULFATE ION × 1 UNKNOWN ATOM OR ION × 17 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 PHD finger protein 1 × 1 （O43189） UNKNOWN ATOM OR ION × 11 water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 2 PHD finger protein 1 × 1 （O43189） UNKNOWN ATOM OR ION × 8 water × 2 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 2 PHD finger protein 1 × 1 （O43189） UNKNOWN ATOM OR ION × 8 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2b2t 2b2u 2b2v 2b2w 2cv5 2l75 2ri7 2uxn 3a1b 3afa 3ayw 3aze

476 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name H31_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain E； PDBConstruct 1–12； UniProt 32–43 Author chain F； PDBConstruct 1–12； UniProt 32–43 Author chain G； PDBConstruct 1–12； UniProt 32–43 Author chain H； PDBConstruct 1–12； UniProt 32–43

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id6wav
Deposition date deposition_date2020-03-26
Structure title titleCrystal structure of PHF1 in complex with H3K36me3 substitution
Keywords keywordsPHF1, Tudor, H3K36me3-H39V, complex, Structural Genomics, Structural Genomics Consortium, SGC, GENE REGULATION; GENE REGULATION
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6wav__assembly_1__model_1 dimeric （2） Excluded — —
Exclusion reason： The source record does not identify the atom or ion element unambiguously, so a reliable calculation is not possible.
2 1 6wav__assembly_2__model_1 dimeric （2） Excluded — —
Exclusion reason： The source record does not identify the atom or ion element unambiguously, so a reliable calculation is not possible.
3 1 6wav__assembly_3__model_1 dimeric （2） Excluded — —
Exclusion reason： The source record does not identify the atom or ion element unambiguously, so a reliable calculation is not possible.
4 1 6wav__assembly_4__model_1 dimeric （2） Excluded — —
Exclusion reason： The source record does not identify the atom or ion element unambiguously, so a reliable calculation is not possible.
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (5)

▶

7. Citations (1)