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6xnw

Crystal structure of V39A mutant of human CEACAM1

Method: X-RAY DIFFRACTION Dmax: 112.2 Å Quality: REASONABLE
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Carcinoembryonic antigen-related cell adhesion molecule 1

Homo sapiens

UniProt P13688

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein homooligomer Homooligomer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain A； UniProt 35–141 Chain B； UniProt 35–141 Mutation：V39A NI NICKEL (II) ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, SITTING DROP；pH 7.5；298 K；0.005 M Cobalt(II) chloride hexahydrate, 0.005 M Nickel(II) chloride hexahydrate, 0.005 M Cadmium chloride hydrate, 0.005 M Magnesium chloride hexahydrate with 12% w/v Polyethylene glycol 3,350 in 0.1 M HEPES pH 7.5 buffer Resolution 1.90 Å R-free 0.186
2 Protein homooligomer Homooligomer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain C； UniProt 35–141 Chain D； UniProt 35–141 Mutation：V39A NI NICKEL (II) ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, SITTING DROP；pH 7.5；298 K；0.005 M Cobalt(II) chloride hexahydrate, 0.005 M Nickel(II) chloride hexahydrate, 0.005 M Cadmium chloride hydrate, 0.005 M Magnesium chloride hexahydrate with 12% w/v Polyethylene glycol 3,350 in 0.1 M HEPES pH 7.5 buffer Resolution 1.90 Å R-free 0.186

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 6XNW Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
2GK2 Crystal structure of the N terminal domain of human CEACAM1 Deposited 2006-03-31 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 34–141（108 aa） Fragment：N terminal domain (residues 63-170)
Not recorded NI NICKEL (II) ION × 1 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；294 K；16% (w/v) polyethylene glycol mono methyl ether 2000, 100 mM Tris, and 5 mM nickel chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K
Resolution 2.20 Å R-free 0.258
2GK2 Crystal structure of the N terminal domain of human CEACAM1 Deposited 2006-03-31 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 34–141（108 aa） Fragment：N terminal domain (residues 63-170)
Not recorded NI NICKEL (II) ION × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；294 K；16% (w/v) polyethylene glycol mono methyl ether 2000, 100 mM Tris, and 5 mM nickel chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K
Resolution 2.20 Å R-free 0.258
2GK2 Crystal structure of the N terminal domain of human CEACAM1 Deposited 2006-03-31 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric
Chain A 34–141（108 aa） Fragment：N terminal domain (residues 63-170)
Chain B 34–141（108 aa） Fragment：N terminal domain (residues 63-170)
Not recorded NI NICKEL (II) ION × 6 GOL GLYCEROL × 9 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；294 K；16% (w/v) polyethylene glycol mono methyl ether 2000, 100 mM Tris, and 5 mM nickel chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K
Resolution 2.20 Å R-free 0.258
2GK2 Crystal structure of the N terminal domain of human CEACAM1 Deposited 2006-03-31 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric
Chain A 34–141（108 aa） Fragment：N terminal domain (residues 63-170)
Chain B 34–141（108 aa） Fragment：N terminal domain (residues 63-170)
Not recorded NI NICKEL (II) ION × 6 GOL GLYCEROL × 9 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；294 K；16% (w/v) polyethylene glycol mono methyl ether 2000, 100 mM Tris, and 5 mM nickel chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K
Resolution 2.20 Å R-free 0.258
2GK2 Crystal structure of the N terminal domain of human CEACAM1 Deposited 2006-03-31 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 34–141（108 aa） Fragment：N terminal domain (residues 63-170)
Chain B 34–141（108 aa） Fragment：N terminal domain (residues 63-170)
Not recorded NI NICKEL (II) ION × 2 GOL GLYCEROL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；294 K；16% (w/v) polyethylene glycol mono methyl ether 2000, 100 mM Tris, and 5 mM nickel chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K
Resolution 2.20 Å R-free 0.258
4QXW Crystal structure of the human CEACAM1 membrane distal amino terminal (N)-domain Deposited 2014-07-22 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 35–141（107 aa） Fragment：N terminal domain
Chain B 35–141（107 aa） Fragment：N terminal domain
Not recorded MLA MALONIC ACID × 1 BOG octyl beta-D-glucopyranoside × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；50 mM TrisHCL buffer 7.5, 60% Tascimate 8.0, 1% Beta-octyl glucoside, 12% Glycerol, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 2.04 Å R-free 0.242
4WHD Human CEACAM1 N-domain homodimer Deposited 2014-09-22 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 34–141（108 aa） Fragment：N-domain (UNP residues 34-141)
Chain B 34–141（108 aa） Fragment：N-domain (UNP residues 34-141)
Not recorded BOG octyl beta-D-glucopyranoside × 8 GOL GLYCEROL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.2；295 K；PEG 3000, NaCl, Phosphate-Citrate
Resolution 2.50 Å R-free 0.226
5DZL Crystal structure of the protein human CEACAM1 Deposited 2015-09-25 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 35–141（107 aa）
Chain B 35–141（107 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；298 K；100 mM Tris 8.0, 25% PEG 3350, 12% glycerol, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 3.40 Å R-free 0.288
5DZL Crystal structure of the protein human CEACAM1 Deposited 2015-09-25 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 35–141（107 aa）
Chain D 35–141（107 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；298 K；100 mM Tris 8.0, 25% PEG 3350, 12% glycerol, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 3.40 Å R-free 0.288
6AW2 Crystal structure of the HopQ-CEACAM1 complex Deposited 2017-09-05 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 34–141（108 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；20% PEG 6000, 0.1M HEPES , pH 7.5, 0.2M NaCl
Resolution 2.68 Å R-free 0.277
6GBG Helicobacter pylori adhesin HopQ type I bound to the N-terminal domain of human CEACAM1 Deposited 2018-04-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain D 35–142（108 aa）
Not recorded BR BROMIDE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；Condition B3 of the Morpheus HT-96 screen (Molecular Dimensions)(0.09 M Halogens mix (0.3M Sodium fluoride; 0.3M Sodium bromide; 0.3M Sodium iodide), 0.1 M Buffer System 1 (1.0M Imidazole; MES monohydrate (acid); pH 6.5), 50 % v/v Precipitant Mix 3 (40% v/v Glycerol; 20% w/v PEG 4000)
Resolution 2.80 Å R-free 0.263
6GBH Helicobacter pylori adhesin HopQ type II bound to the N-terminal domain of human CEACAM1 Deposited 2018-04-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 35–142（108 aa）
Not recorded SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；Condition A4 of the JB Screen Classic HTS II screen (Jena Bioscience) (1 M Ammonium sulfate, 100 mM Tris; pH 8.5)
Resolution 2.59 Å R-free 0.274
6GBH Helicobacter pylori adhesin HopQ type II bound to the N-terminal domain of human CEACAM1 Deposited 2018-04-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain D 35–142（108 aa）
Not recorded SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；Condition A4 of the JB Screen Classic HTS II screen (Jena Bioscience) (1 M Ammonium sulfate, 100 mM Tris; pH 8.5)
Resolution 2.59 Å R-free 0.274
6V3P The BIgI domain of beta protein from S. agalactiae bound to CEACAM1 Deposited 2019-11-26 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 34–141（108 aa）
Not recorded SO4 SULFATE ION × 4 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；1.7M Ammonium Sulfate, 0.1M Sodium Citrate, pH 5.5
Resolution 3.25 Å R-free 0.244
6V3P The BIgI domain of beta protein from S. agalactiae bound to CEACAM1 Deposited 2019-11-26 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 34–141（108 aa）
Not recorded SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；1.7M Ammonium Sulfate, 0.1M Sodium Citrate, pH 5.5
Resolution 3.25 Å R-free 0.244
6XNO Crystal structure of E99A mutant of human CEACAM1 Deposited 2020-07-03 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 35–141（107 aa）
Chain B 35–141（107 aa）
Mutation：E99A Mutation：E99A BOG octyl beta-D-glucopyranoside × 2 MLA MALONIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；41% Tascimate with 0.5 % n-Octyl-D-glucoside pH 8.0
Resolution 1.90 Å R-free 0.223
6XNT Crystal structure of I91A mutant of human CEACAM1 Deposited 2020-07-04 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 35–141（107 aa）
Chain B 35–141（107 aa）
Mutation：I91A Mutation：I91A BOG octyl beta-D-glucopyranoside × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；54% Tascimate with 0.5 % n-Octyl-D-glucoside pH 8.0
Resolution 3.10 Å R-free 0.258
6XO1 Crystal structure of N97A mutant of human CEACAM1 Deposited 2020-07-05 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 35–141（107 aa）
Mutation：N97A MLA MALONIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；298 K；6% Tascimate with 25% polyethylene glycol 400 in 0.1 M MES monohydrate pH 6.0
Resolution 1.76 Å R-free 0.240
6XO1 Crystal structure of N97A mutant of human CEACAM1 Deposited 2020-07-05 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 35–141（107 aa）
Mutation：N97A MLA MALONIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；298 K；6% Tascimate with 25% polyethylene glycol 400 in 0.1 M MES monohydrate pH 6.0
Resolution 1.76 Å R-free 0.240
7MU8 Structure of the minimally glycosylated human CEACAM1 N-terminal domain Deposited 2021-05-14 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 35–141（107 aa）
Chain B 35–141（107 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 GOL GLYCEROL × 10 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；291 K；100 mM MES, pH 6.5, 2M Ammonium sulfate
Resolution 1.70 Å R-free 0.217
7RPP Crystal structure of human CEACAM1 with GFCC' and ABED face Deposited 2021-08-04 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 35–141（107 aa）
Not recorded EDO 1,2-ETHANEDIOL × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；298 K；0.2 M Ammonium sulfate, 0.1 M HEPES pH 7.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.20 Å R-free 0.237
7RPP Crystal structure of human CEACAM1 with GFCC' and ABED face Deposited 2021-08-04 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain B 35–141（107 aa）
Chain C 35–141（107 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；298 K；0.2 M Ammonium sulfate, 0.1 M HEPES pH 7.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.20 Å R-free 0.237
8CXJ The IgI3 domain of R28 protein from S. pyogenes bound to CEACAM1 Deposited 2022-05-21 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 34–141（108 aa）
Not recorded GOL GLYCEROL × 2 SO4 SULFATE ION × 4 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；1.45 M Ammonium sulfate 0.1M Na/K Phosphate pH 5.5
Resolution 3.05 Å R-free 0.238
8CXJ The IgI3 domain of R28 protein from S. pyogenes bound to CEACAM1 Deposited 2022-05-21 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 34–141（108 aa）
Not recorded GOL GLYCEROL × 2 SO4 SULFATE ION × 4 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；1.45 M Ammonium sulfate 0.1M Na/K Phosphate pH 5.5
Resolution 3.05 Å R-free 0.238
8CXJ The IgI3 domain of R28 protein from S. pyogenes bound to CEACAM1 Deposited 2022-05-21 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 34–141（108 aa）
Not recorded GOL GLYCEROL × 1 SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；1.45 M Ammonium sulfate 0.1M Na/K Phosphate pH 5.5
Resolution 3.05 Å R-free 0.238
8CXJ The IgI3 domain of R28 protein from S. pyogenes bound to CEACAM1 Deposited 2022-05-21 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 34–141（108 aa）
Not recorded SO4 SULFATE ION × 2 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；1.45 M Ammonium sulfate 0.1M Na/K Phosphate pH 5.5
Resolution 3.05 Å R-free 0.238
9GH5 Complex of Fusobacterium nucleatum CbpF with human CEACAM1 Deposited 2024-08-15 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric
Chain D 35–428（394 aa）
Chain E 35–428（394 aa）
Chain F 35–428（394 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 18 ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.70 Å
9GH6 CEACAM1 (35-234), focused refinement in the complex with CbpF Deposited 2024-08-15 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 1–428（428 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 7 ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
9U94 Cryo-EM structure of Fusobacterium nucleatum CbpF in complex with human CEACAM1 Deposited 2025-03-27 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric
Chain D 35–141（107 aa）
Chain E 35–141（107 aa）
Chain F 35–141（107 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.11 Å

17 other PDB entries and 29 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name CEAM1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–107； UniProt 35–141 Author chain B； PDBConstruct 1–107； UniProt 35–141 Author chain C； PDBConstruct 1–107； UniProt 35–141 Author chain D； PDBConstruct 1–107； UniProt 35–141

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

SAXS profile for 6xnw

P(r) Distance Distribution P(r) Distribution

P(r) distribution for 6xnw
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2. Structure Basics 2. Structure Basics

Entry ID entry_id6xnw
Deposition date deposition_date2020-07-04
Structure title titleCrystal structure of V39A mutant of human CEACAM1
Keywords keywordsCEACAM1, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodX-RAY DIFFRACTION
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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier30.61 Å
Radius of gyration Rg (electron density) rg_electron30.88 Å
Forward intensity I(0) i037581800.00
Molecular weight molecular_weight47554.0 kDa
Excluded volume excluded_volume59219 ų
Envelope volume envelope_volume73436 ų
Hydration-shell volume shell_volume22835 ų
Envelope diameter envelope_diameter118.7 Å
Shell Rg shell_rg32.92 Å
Envelope Rg envelope_rg30.96 Å
Shape Rg shape_rg30.85 Å
Total Rg total_rg31.16 Å
Total atoms total_atoms3358
Residues n_residues428
Spherical-harmonic order n_harmonics20
q range q_range— – 0.5000 Å−1
Data points n_points101
Shell type shell_typedirectional
Solvent electron density solvent_density0.3340 e/ų
Shell contrast contrast_shell0.0300 e/ų
CRYSOL version crysol_version4.1.3
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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax112.2 Å
Rg (real space) rg_real31.17 Å
Rg uncertainty (real space) rg_real_error1.18 Å
I(0) (real space) i0_real3.7580e+07
I(0) uncertainty (real space) i0_real_error5.8850e+05
Rg (reciprocal space) rg_reciprocal30.93 Å
I(0) (reciprocal space) i0_reciprocal37570000.0000
Solution quality estimate total_estimate0.7250
Solution quality rating solution_quality REASONABLE a REASONABLE solution
P(r) peaks n_peaks2
Primary peak position r_peak_primary23.7 Å
Skewness Skewness skewness0.688
Kurtosis Kurtosis kurtosis-0.071
Angular range angular_range— – 0.2600 Å−1
Current regularization parameter α current_alpha0.0000
Highest regularization parameter α highest_alpha10210000.0000
Real-space data points n_real_points53
GNOM version gnom_version4.1.3
Quality Criteria quality_criteria AN1: 0.000; Oscil: 0.473; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.226; Smooth: 0.777
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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (3)

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8. Citations (1)

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9. Files and Curves (10)