6ybd

Structure of a human 48S translational initiation complex - eIF3

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Eukaryotic translation initiation factor 3 subunit M

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3M_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain 6； PDBConstruct 1–374； UniProt 1–374

Eukaryotic translation initiation factor 3 subunit F

OrganismNot specified

UniProt O00303

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3F_HUMAN
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain 4； PDBConstruct 1–357； UniProt 1–357

Eukaryotic translation initiation factor 3 subunit A

OrganismNot specified

UniProt Q14152

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3A_HUMAN
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain u； PDBConstruct 1–1382； UniProt 1–1382

Eukaryotic translation initiation factor 3 subunit E

OrganismNot specified

UniProt P60228

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3E_HUMAN
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain v； PDBConstruct 1–445； UniProt 1–445

Eukaryotic translation initiation factor 3 subunit C

OrganismNot specified

UniProt Q99613

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3C_HUMAN
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain y； PDBConstruct 1–913； UniProt 1–913

Eukaryotic translation initiation factor 3 subunit H

OrganismNot specified

UniProt O15372

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3H_HUMAN
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain 8； PDBConstruct 1–352； UniProt 1–352

40S ribosomal protein S7

OrganismNot specified

UniProt P62081

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS7_HUMAN
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain G； PDBConstruct 1–194； UniProt 1–194

40S ribosomal protein S27

OrganismNot specified

UniProt P42677

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS27_HUMAN
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain H； PDBConstruct 1–84； UniProt 1–84

40S ribosomal protein S21

OrganismNot specified

UniProt P63220

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS21_HUMAN
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain K； PDBConstruct 1–83； UniProt 1–83

40S ribosomal protein S17

OrganismNot specified

UniProt P08708

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS17_HUMAN
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain M； PDBConstruct 1–135； UniProt 1–135

40S ribosomal protein S2

OrganismNot specified

UniProt P15880

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS2_HUMAN
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain L； PDBConstruct 1–293； UniProt 1–293

40S ribosomal protein S3a

OrganismNot specified

UniProt P61247

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS3A_HUMAN
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain O； PDBConstruct 1–264； UniProt 1–264

40S ribosomal protein SA

OrganismNot specified

UniProt P08865

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RSSA_HUMAN
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain N； PDBConstruct 1–295； UniProt 1–295

40S ribosomal protein S26

OrganismNot specified

UniProt P62854

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS26_HUMAN
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain Q； PDBConstruct 1–115； UniProt 1–115

40S ribosomal protein S14

OrganismNot specified

UniProt P62263

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS14_HUMAN
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain P； PDBConstruct 1–151； UniProt 1–151

40S ribosomal protein S13

OrganismNot specified

UniProt P62277

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS13_HUMAN
Isoform	—
PDB entities	16
Chains and sequence ranges	Author chain I； PDBConstruct 1–151； UniProt 1–151

Eukaryotic translation initiation factor 3 subunit D

OrganismNot specified

UniProt O15371

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3D_HUMAN
Isoform	—
PDB entities	17
Chains and sequence ranges	Author chain x； PDBConstruct 1–548； UniProt 1–548

Eukaryotic translation initiation factor 3 subunit K

OrganismNot specified

UniProt Q9UBQ5

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit L × 1 （Q9Y262）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3K_HUMAN
Isoform	—
PDB entities	18
Chains and sequence ranges	Author chain 3； PDBConstruct 1–218； UniProt 1–218

Eukaryotic translation initiation factor 3 subunit L

OrganismNot specified

UniProt Q9Y262

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 19	Eukaryotic translation initiation factor 3 subunit M × 1 （Q7L2H7） Eukaryotic translation initiation factor 3 subunit F × 1 （O00303） Eukaryotic translation initiation factor 3 subunit A × 1 （Q14152） Eukaryotic translation initiation factor 3 subunit E × 1 （P60228） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） Eukaryotic translation initiation factor 3 subunit H × 1 （O15372） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit D × 1 （O15371） Eukaryotic translation initiation factor 3 subunit K × 1 （Q9UBQ5）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3L_HUMAN
Isoform	—
PDB entities	19
Chains and sequence ranges	Author chain 5； PDBConstruct 1–564； UniProt 1–564

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	6ybd
Deposition date deposition_date	2020-03-16
Structure title title	Structure of a human 48S translational initiation complex - eIF3
Keywords keywords	eIF3, ribosome, translation, initiation complex; TRANSLATION
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6ybd__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6ybd__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

6ybd__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	65.35 Å
Rg (electron density)	64.65 Å
Total Rg	64.47 Å
Atom count	30734
Residues	4421
Excluded volume	536490 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`6ybd__assembly_1__model_1`	nonadecameric （19）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (19)

Entity 1 Entity 1 polymer

Description description	Eukaryotic translation initiation factor 3 subunit M
Molecular weight formula_weight	42555.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	6
Atom count atom_count	30742

MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLSLSDT

Entity 2 Entity 2 polymer

Description description	Eukaryotic translation initiation factor 3 subunit F
Molecular weight formula_weight	37593.6 kDa
EC 编号 ec_number	3.4.19.12
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	4

MATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQAPAQTPAPALPGPALPGPFPGGRVVRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAVDMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPNPIHLTVDTSLQNGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTCFSPNRVIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL

Entity 3 Entity 3 polymer

Description description	Eukaryotic translation initiation factor 3 subunit A
Molecular weight formula_weight	166903.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	u

MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLTQDEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQAPPTRIGLINDMVRFNVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR

Entity 4 Entity 4 polymer

Description description	Eukaryotic translation initiation factor 3 subunit E
Molecular weight formula_weight	52281.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	v

MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKNLYSDDIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRSEAPNWATQDSGFY

Entity 5 Entity 5 polymer

Description description	Eukaryotic translation initiation factor 3 subunit C
Molecular weight formula_weight	105503.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	y

MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMRRGGYRQQQSQTAY

Entity 6 Entity 6 polymer

Description description	Eukaryotic translation initiation factor 3 subunit H
Molecular weight formula_weight	39979.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	8

MASRKEGTGSTATSSSSTAGAAGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPEALKKANITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYNN

Entity 7 Entity 7 polymer

Description description	40S ribosomal protein S7
Molecular weight formula_weight	22168.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G

MFSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL

Entity 8 Entity 8 polymer

Description description	40S ribosomal protein S27
Molecular weight formula_weight	9480.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH

Entity 9 Entity 9 polymer

Description description	40S ribosomal protein S21
Molecular weight formula_weight	9124.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K

MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEVDKVTGRFNGQFKTYAICGAIRRMGESDDSILRLAKADGIVSKNF

Entity 10 Entity 10 polymer

Description description	40S ribosomal protein S17
Molecular weight formula_weight	15578.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	M

MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGPV

Entity 11 Entity 11 polymer

Description description	40S ribosomal protein S2
Molecular weight formula_weight	31376.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L

MADDAGAAGGPGGPGGPGMGNRGGFRGGFGSGIRGRGRGRGRGRGRGRGARGGKAEDKEWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSVQRTQAPAVATT

Entity 12 Entity 12 polymer

Description description	40S ribosomal protein S3a
Molecular weight formula_weight	30002.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	O

MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV

Entity 13 Entity 13 polymer

Description description	40S ribosomal protein SA
Molecular weight formula_weight	32883.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N

MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAAEKAVTKEEFQGEWTAPAPEFTATQPEVADWSEGVQVPSVPIQQFPTEDWSAQPATEDWSAAPTAQATEWVGATTDWS

Entity 14 Entity 14 polymer

Description description	40S ribosomal protein S26
Molecular weight formula_weight	13047.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Q

MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPRFRPAGAAPRPPPKPM

Entity 15 Entity 15 polymer

Description description	40S ribosomal protein S14
Molecular weight formula_weight	16302.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	P

MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Entity 16 Entity 16 polymer

Description description	40S ribosomal protein S13
Molecular weight formula_weight	17259.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA

Entity 17 Entity 17 polymer

Description description	Eukaryotic translation initiation factor 3 subunit D
Molecular weight formula_weight	64060.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	x

MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDESSFQLVDTARTQKTAYQRNRMRFAQRNLRRDKDRRNMLQFNLQILPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQKPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGKERYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYSLPDGTFSSDEDEEEEEEEEEEEEEEET

Entity 18 Entity 18 polymer

Description description	Eukaryotic translation initiation factor 3 subunit K
Molecular weight formula_weight	25083.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	3

MAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLSDSQLKVWMSKYGWSADESGQIFICSQEESIKPKNIVEKIDFDSVSSIMASSQ

Entity 19 Entity 19 polymer

Description description	Eukaryotic translation initiation factor 3 subunit L
Molecular weight formula_weight	66803.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	5

MSYPADDYESEAAYDPYAYPSDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	triclinic

Resolution resolution	3.30 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	11882

Structure of a human 48S translational initiation complex - eIF3

1. Protein Identity and Related Structures Protein Identity & Related Structures

Eukaryotic translation initiation factor 3 subunit M

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Eukaryotic translation initiation factor 3 subunit F

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Eukaryotic translation initiation factor 3 subunit A

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Eukaryotic translation initiation factor 3 subunit E

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Eukaryotic translation initiation factor 3 subunit C

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Eukaryotic translation initiation factor 3 subunit H

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S7

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S27

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S21

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S17

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer