6ybw

Structure of a human 48S translational initiation complex - 40S body

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

40S ribosomal protein S4, X isoform

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS4X_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain C； PDBConstruct 1–263； UniProt 1–263

40S ribosomal protein S11

OrganismNot specified

UniProt P62280

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS11_HUMAN
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 1–157； UniProt 1–157

40S ribosomal protein S23

OrganismNot specified

UniProt P62266

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS23_HUMAN
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain E； PDBConstruct 1–143； UniProt 1–143

40S ribosomal protein S9

OrganismNot specified

UniProt P46781

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS9_HUMAN
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain D； PDBConstruct 1–194； UniProt 1–194

40S ribosomal protein S7

OrganismNot specified

UniProt P62081

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS7_HUMAN
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain G； PDBConstruct 1–194； UniProt 1–194

40S ribosomal protein S30

OrganismNot specified

UniProt P62861

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS30_HUMAN
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain F； PDBConstruct 1–59； UniProt 1–59

40S ribosomal protein S27

OrganismNot specified

UniProt P42677

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS27_HUMAN
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain H； PDBConstruct 1–84； UniProt 1–84

40S ribosomal protein S21

OrganismNot specified

UniProt P63220

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS21_HUMAN
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain K； PDBConstruct 1–83； UniProt 1–83

40S ribosomal protein S15a

OrganismNot specified

UniProt P62244

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS15A_HUMAN
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain J； PDBConstruct 1–130； UniProt 1–130

40S ribosomal protein S17

OrganismNot specified

UniProt P08708

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS17_HUMAN
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain M； PDBConstruct 1–135； UniProt 1–135

40S ribosomal protein S2

OrganismNot specified

UniProt P15880

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS2_HUMAN
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain L； PDBConstruct 1–293； UniProt 1–293

40S ribosomal protein S3a

OrganismNot specified

UniProt P61247

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS3A_HUMAN
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain O； PDBConstruct 1–264； UniProt 1–264

40S ribosomal protein SA

OrganismNot specified

UniProt P08865

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RSSA_HUMAN
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain N； PDBConstruct 1–295； UniProt 1–295

40S ribosomal protein S26

OrganismNot specified

UniProt P62854

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS26_HUMAN
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain Q； PDBConstruct 1–115； UniProt 1–115

40S ribosomal protein S14

OrganismNot specified

UniProt P62263

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS14_HUMAN
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain P； PDBConstruct 1–151； UniProt 1–151

40S ribosomal protein S6

OrganismNot specified

UniProt P62753

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS6_HUMAN
Isoform	—
PDB entities	16
Chains and sequence ranges	Author chain S； PDBConstruct 1–249； UniProt 1–249

40S ribosomal protein S8

OrganismNot specified

UniProt P62241

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS8_HUMAN
Isoform	—
PDB entities	17
Chains and sequence ranges	Author chain R； PDBConstruct 1–208； UniProt 1–208

40S ribosomal protein S24

OrganismNot specified

UniProt P62847

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS24_HUMAN
Isoform	—
PDB entities	18
Chains and sequence ranges	Author chain T； PDBConstruct 1–133； UniProt 1–133

Eukaryotic translation initiation factor 1A, X-chromosomal

Homo sapiens

UniProt P47813

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	IF1AX_HUMAN
Isoform	—
PDB entities	19
Chains and sequence ranges	Author chain q； PDBConstruct 1–144； UniProt 1–144

Eukaryotic translation initiation factor 1

Homo sapiens

UniProt P41567

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF1_HUMAN
Isoform	—
PDB entities	20
Chains and sequence ranges	Author chain p； PDBConstruct 1–113； UniProt 1–113

40S ribosomal protein S13

OrganismNot specified

UniProt P62277

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS13_HUMAN
Isoform	—
PDB entities	21
Chains and sequence ranges	Author chain I； PDBConstruct 1–151； UniProt 1–151

Eukaryotic translation initiation factor 3 subunit J

Homo sapiens

UniProt O75822

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3J_HUMAN
Isoform	—
PDB entities	22
Chains and sequence ranges	Author chain z； PDBConstruct 1–258； UniProt 1–258

Eukaryotic translation initiation factor 3 subunit C

OrganismNot specified

UniProt Q99613

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） 60S ribosomal protein L41 × 1 （P62945） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	EIF3C_HUMAN
Isoform	—
PDB entities	23
Chains and sequence ranges	Author chain y； PDBConstruct 1–913； UniProt 1–913

60S ribosomal protein L41

OrganismNot specified

UniProt P62945

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 24 RNA 2	40S ribosomal protein S4, X isoform × 1 （P62701） 40S ribosomal protein S11 × 1 （P62280） 40S ribosomal protein S23 × 1 （P62266） 40S ribosomal protein S9 × 1 （P46781） 40S ribosomal protein S7 × 1 （P62081） 40S ribosomal protein S30 × 1 （P62861） 40S ribosomal protein S27 × 1 （P42677） 40S ribosomal protein S21 × 1 （P63220） 40S ribosomal protein S15a × 1 （P62244） 40S ribosomal protein S17 × 1 （P08708） 40S ribosomal protein S2 × 1 （P15880） 40S ribosomal protein S3a × 1 （P61247） 40S ribosomal protein SA × 1 （P08865） 40S ribosomal protein S26 × 1 （P62854） 40S ribosomal protein S14 × 1 （P62263） 40S ribosomal protein S6 × 1 （P62753） 40S ribosomal protein S8 × 1 （P62241） 40S ribosomal protein S24 × 1 （P62847） Eukaryotic translation initiation factor 1A, X-chromosomal × 1 （P47813） Eukaryotic translation initiation factor 1 × 1 （P41567） 40S ribosomal protein S13 × 1 （P62277） Eukaryotic translation initiation factor 3 subunit J × 1 （O75822） Eukaryotic translation initiation factor 3 subunit C × 1 （Q99613） 18S rRNA × 1 mRNA × 1 MAGNESIUM ION × 60 ZINC ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL41_HUMAN
Isoform	—
PDB entities	24
Chains and sequence ranges	Author chain 9； PDBConstruct 1–25； UniProt 1–25

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	6ybw
Deposition date deposition_date	2020-03-18
Structure title title	Structure of a human 48S translational initiation complex - 40S body
Keywords keywords	eIF3, ribosome, translation, initiation complex; TRANSLATION
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6ybw__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6ybw__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

6ybw__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	61.42 Å
Rg (electron density)	62.25 Å
Total Rg	62.24 Å
Atom count	52840
Residues	4598
Excluded volume	847650 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`6ybw__assembly_1__model_1`	26-meric （26）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (28)

Entity 1 Entity 1 polymer

Description description	40S ribosomal protein S4, X isoform
Molecular weight formula_weight	29654.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C
Atom count atom_count	52840

MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG

Entity 2 Entity 2 polymer

Description description	40S ribosomal protein S11
Molecular weight formula_weight	18321.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

MADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKKQFQK

Entity 3 Entity 3 polymer

Description description	40S ribosomal protein S23
Molecular weight formula_weight	15844.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

MGKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS

Entity 4 Entity 4 polymer

Description description	40S ribosomal protein S9
Molecular weight formula_weight	22641.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D

MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED

Entity 5 Entity 5 polymer

Description description	40S ribosomal protein S7
Molecular weight formula_weight	22168.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G

MFSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL

Entity 6 Entity 6 polymer

Description description	40S ribosomal protein S30
Molecular weight formula_weight	6668.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F

KVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPNANS

Entity 7 Entity 7 polymer

Description description	40S ribosomal protein S27
Molecular weight formula_weight	9480.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH

Entity 8 Entity 8 polymer

Description description	40S ribosomal protein S21
Molecular weight formula_weight	9124.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K

MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEVDKVTGRFNGQFKTYAICGAIRRMGESDDSILRLAKADGIVSKNF

Entity 9 Entity 9 polymer

Description description	40S ribosomal protein S15a
Molecular weight formula_weight	14865.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J

MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF

Entity 10 Entity 10 polymer

Description description	40S ribosomal protein S17
Molecular weight formula_weight	15578.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	M

MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGPV

Entity 11 Entity 11 polymer

Description description	40S ribosomal protein S2
Molecular weight formula_weight	31376.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L

MADDAGAAGGPGGPGGPGMGNRGGFRGGFGSGIRGRGRGRGRGRGRGRGARGGKAEDKEWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSVQRTQAPAVATT

Entity 12 Entity 12 polymer

Description description	40S ribosomal protein S3a
Molecular weight formula_weight	30002.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	O

MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV

Entity 13 Entity 13 polymer

Description description	40S ribosomal protein SA
Molecular weight formula_weight	32883.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N

MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAAEKAVTKEEFQGEWTAPAPEFTATQPEVADWSEGVQVPSVPIQQFPTEDWSAQPATEDWSAAPTAQATEWVGATTDWS

Entity 14 Entity 14 polymer

Description description	40S ribosomal protein S26
Molecular weight formula_weight	13047.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Q

MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPRFRPAGAAPRPPPKPM

Entity 15 Entity 15 polymer

Description description	40S ribosomal protein S14
Molecular weight formula_weight	16302.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	P

MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Entity 16 Entity 16 polymer

Description description	40S ribosomal protein S6
Molecular weight formula_weight	28751.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	S

MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK

Entity 17 Entity 17 polymer

Description description	40S ribosomal protein S8
Molecular weight formula_weight	24263.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	R

MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKGK

Entity 18 Entity 18 polymer

Description description	40S ribosomal protein S24
Molecular weight formula_weight	15463.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	T

MNDTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAGKKPKE

Entity 19 Entity 19 polymer

Description description	Eukaryotic translation initiation factor 1A, X-chromosomal
Molecular weight formula_weight	16488.4 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	q

MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDDI

Source Source

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Entity 20 Entity 20 polymer

Description description	Eukaryotic translation initiation factor 1
Molecular weight formula_weight	12752.5 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	p

MSAIQNLHSFDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLVEIGLAKDDQLKVHGF

Source Source

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Entity 21 Entity 21 polymer

Description description	40S ribosomal protein S13
Molecular weight formula_weight	17259.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA

Entity 22 Entity 22 polymer

Description description	Eukaryotic translation initiation factor 3 subunit J
Molecular weight formula_weight	29108.5 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	z

MAAAAAAAGDSDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYDGGYVQDYEDFM

Source Source

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Entity 23 Entity 23 polymer

Description description	Eukaryotic translation initiation factor 3 subunit C
Molecular weight formula_weight	105503.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	y

MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMRRGGYRQQQSQTAY

Entity 24 Entity 24 polymer

Description description	60S ribosomal protein L41
Molecular weight formula_weight	3473.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	9

MRAKWRKKRMRRLKRKRRKMRQRSK

Entity 25 Entity 25 polymer

Description description	18S rRNA
Molecular weight formula_weight	603130.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	A

UACCUGGUUGAUCCUGCCAGUAGCAUAUGCUUGUCUCAAAGAUUAAGCCAUGCAUGUCUGAGUACGCACGGCCGGUACAGUGAAACUGCGAAUGGCUCAUUAAAUCAGUUAUGGUUCCUUUGGUCGCUCGCUCCUCUCCUACUUGGAUAACUGUGGUAAUUCUAGAGCUAAUACAUGCCGACGGGCGCUGACCCCCUUCGCGGGGGGGAUGCGUGCAUUUAUCAGAUCAAAACCAACCCGGUCAGCCCCUCUCCGGCCCCGGCCGGGGGGCGGGCGCCGGCGGCUUUGGUGACUCUAGAUAACCUCGGGCCGAUCGCACGCCCCCCGUGGCGGCGACGACCCAUUCGAACGUCUGCCCUAUCAACUUUCGAUGGUAGUCGCCGUGCCUACCAUGGUGACCACGGGUGACGGGGAAUCAGGGUUCGAUUCCGGAGAGGGAGCCUGAGAAACGGCUACCACAUCCAAGGAAGGCAGCAGGCGCGCAAAUUACCCACUCCCGACCCGGGGAGGUAGUGACGAAAAAUAACAAUACAGGACUCUUUCGAGGCCCUGUAAUUGGAAUGAGUCCACUUUAAAUCCUUUAACGAGGAUCCAUUGGAGGGCAAGUCUGGUGCCAGCAGCCGCGGUAAUUCCAGCUCCAAUAGCGUAUAUUAAAGUUGCUGCAGUUAAAAAGCUCGUAGUUGGAUCUUGGGAGCGGGCGGGCGGUCCGCCGCGAGGCGAGCCACCGCCCGUCCCCGCCCCUUGCCUCUCGGCGCCCCCUCGAUGCUCUUAGCUGAGUGUCCCGCGGGGCCCGAAGCGUUUACUUUGAAAAAAUUAGAGUGUUCAAAGCAGGCCCGAGCCGCCUGGAUACCGCAGCUAGGAAUAAUGGAAUAGGACCGCGGUUCUAUUUUGUUGGUUUUCGGAACUGAGGCCAUGAUUAAGAGGGACGGCCGGGGGCAUUCGUAUUGCGCCGCUAGAGGUGAAAUUCUUGGACCGGCGCAAGACGGACCAGAGCGAAAGCAUUUGCCAAGAAUGUUUUCAUUAAUCAAGAACGAAAGUCGGAGGUUCGAAGACGAUCAGAUACCGUCGUAGUUCCGACCAUAAACGAUGCCGACCGGCGAUGCGGCGGCGUUAUUCCCAUGACCCGCCGGGCAGCUUCCGGGAAACCAAAGUCUUUGGGUUCCGGGGGGAGUAUGGUUGCAAAGCUGAAACUUAAAGGAAUUGACGGAAGGGCACCACCAGGAGUGGAGCCUGCGGCUUAAUUUGACUCAACACGGGAAACCUCACCCGGCCCGGACACGGACAGGAUUGACAGAUUGAUAGCUCUUUCUCGAUUCCGUGGGUGGUGGUGCAUGGCCGUUCUUAGUUGGUGGAGCGAUUUGUCUGGUUAAUUCCGAUAACGAACGAGACUCUGGCAUGCUAACUAGUUACGCGACCCCCGAGCGGUCGGCGUCCCCCAACUUCUUAGAGGGACAAGUGGCGUUCAGCCACCCGAGAUUGAGCAAUAACAGGUCUGUGAUGCCCUUAGAUGUCCGGGGCUGCACGCGCGCUACACUGACUGGCUCAGCGUGUGCCUACCCUACGCCGGCAGGCGCGGGUAACCCGUUGAACCCCAUUCGUGAUGGGGAUCGGGGAUUGCAAUUAUUCCCCAUGAACGAGGAAUUCCCAGUAAGUGCGGGUCAUAAGCUUGCGUUGAUUAAGUCCCUGCCCUUUGUACACACCGCCCGUCGCUACUACCGAUUGGAUGGUUUAGUGAGGCCCUCGGAUCGGCCCCGCCGGGGUCGGCCCACGGCCCUGGCGGAGCGCUGAGAAGACGGUCGAACUUGACUAUCUAGAGGAAGUAAAAGUCGUAACAAGGUUUCCGUAGGUGAACCUGCGGAAGGAUCAUUA

Entity 26 Entity 26 polymer

Description description	mRNA
Molecular weight formula_weight	9172.8 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	7

AAAAAAAAAAAAAAAAAAAAAAAAAAAA

Entity 27 Entity 27 non-polymer

Description description	MAGNESIUM ION
Molecular weight formula_weight	24.3 kDa
Source method src_method	syn
Copy count entity_count	60

Entity 28 Entity 28 non-polymer

Description description	ZINC ION
Molecular weight formula_weight	65.4 kDa
Source method src_method	syn
Copy count entity_count	1

▶

Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	triclinic

Resolution resolution	3.10 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	144882

Structure of a human 48S translational initiation complex - 40S body

1. Protein Identity and Related Structures Protein Identity & Related Structures

40S ribosomal protein S4, X isoform

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S11

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S23

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S9

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S7

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S30

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S27

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S21

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S15a

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

40S ribosomal protein S17

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer