6zk9

Peripheral domain of open complex I during turnover

Method: ELECTRON MICROSCOPY
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

物种未注明

UniProt W5PUX0

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5PUX0_SHEEP
Isoform —
PDB实体 1
链与序列区间 作者链 1; PDB构建体 1–464; UniProt 1–464

Mitochondrial complex I, 24 kDa subunit

物种未注明

UniProt W5NRY1

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5NRY1_SHEEP
Isoform —
PDB实体 2
链与序列区间 作者链 2; PDB构建体 1–246; UniProt 1–246

NADH:ubiquinone oxidoreductase core subunit S1

物种未注明

UniProt W5QB34

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5QB34_SHEEP
Isoform —
PDB实体 3
链与序列区间 作者链 3; PDB构建体 1–727; UniProt 1–727

NADH:ubiquinone oxidoreductase core subunit S3

物种未注明

UniProt W5PB27

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5PB27_SHEEP
Isoform —
PDB实体 5
链与序列区间 作者链 5; PDB构建体 1–266; UniProt 1–266

NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

物种未注明

UniProt W5PE07

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5PE07_SHEEP
Isoform —
PDB实体 10
链与序列区间 作者链 c; PDB构建体 1–170; UniProt 1–170

NADH:ubiquinone oxidoreductase subunit A9

物种未注明

UniProt W5PI58

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5PI58_SHEEP
Isoform —
PDB实体 11
链与序列区间 作者链 d; PDB构建体 1–380; UniProt 1–380

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

物种未注明

UniProt W5QAH8

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5QAH8_SHEEP
Isoform —
PDB实体 12
链与序列区间 作者链 e; PDB构建体 1–99; UniProt 1–99

Mitochondrial complex I, B13 subunit

物种未注明

UniProt W5PNX7

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5PNX7_SHEEP
Isoform —
PDB实体 13
链与序列区间 作者链 f; PDB构建体 1–116; UniProt 1–116

NADH:ubiquinone oxidoreductase subunit A6

物种未注明

UniProt W5QC06

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5QC06_SHEEP
Isoform —
PDB实体 14
链与序列区间 作者链 g; PDB构建体 1–140; UniProt 1–140

Mitochondrial complex I, B14.5a subunit

物种未注明

UniProt W5P0I2

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5P0I2_SHEEP
Isoform —
PDB实体 15
链与序列区间 作者链 h; PDB构建体 1–114; UniProt 1–114

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

物种未注明

UniProt B9VGZ9

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) Acyl carrier protein × 1 (W5NQT7) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 B9VGZ9_SHEEP
Isoform —
PDB实体 16
链与序列区间 作者链 i; PDB构建体 1–145; UniProt 1–145

Acyl carrier protein

物种未注明

UniProt W5NQT7

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 18 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial × 1 (W5PUX0) Mitochondrial complex I, 24 kDa subunit × 1 (W5NRY1) NADH:ubiquinone oxidoreductase core subunit S1 × 1 (W5QB34) Mitochondrial complex I, 49 kDa subunit × 1 NADH:ubiquinone oxidoreductase core subunit S3 × 1 (W5PB27) Mitochondrial complex I, PSST subunit × 1 Mitochondrial complex I, TYKY subunit × 1 Mitochondrial complex I, 10 kDa subunit × 1 Mitochondrial complex I, 13 kDa subunit × 1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial × 1 (W5PE07) NADH:ubiquinone oxidoreductase subunit A9 × 1 (W5PI58) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 × 1 (W5QAH8) Mitochondrial complex I, B13 subunit × 1 (W5PNX7) NADH:ubiquinone oxidoreductase subunit A6 × 1 (W5QC06) Mitochondrial complex I, B14.5a subunit × 1 (W5P0I2) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 × 1 (B9VGZ9) Mitochondrial complex I, B16.6 subunit × 1 IRON/SULFUR CLUSTER × 6 FLAVIN MONONUCLEOTIDE × 1 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 FE2/S2 (INORGANIC) CLUSTER × 2 POTASSIUM ION × 1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 ZINC ION × 1 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate × 1 CARDIOLIPIN × 1 water × 17 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 W5NQT7_SHEEP
Isoform —
PDB实体 17
链与序列区间 作者链 j; PDB构建体 1–157; UniProt 1–157

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id6zk9
沉积日期 deposition_date2020-06-30
结构标题 titlePeripheral domain of open complex I during turnover
关键词 keywordscomplex, respiration, NADH, proton pump, mitochondria, iron-sulphur cluster, oxidoreductase, membrane protein, ELECTRON TRANSPORT; ELECTRON TRANSPORT
实验方法 methodELECTRON MICROSCOPY
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

6zk9__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

6zk9__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

6zk9__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)48.15 Å
Rg(电子密度)48.30 Å
总 Rg48.30 Å
原子数28115
残基数3478
排除体积502300 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 6zk9__assembly_1__model_1 octadecameric (18) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (30)

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6. 折叠分类 (SCOP + CATH) 6 domains

SCOP 2.08 (6 domains)

结构域编号 domain_idd6zk911
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.142 — Nqo1 FMN-binding domain-like
超家族 Superfamily superfamilyc.142.1 — Nqo1 FMN-binding domain-like
家族 Family familyc.142.1.0 — automated matches
结构域编号 domain_idd6zk912
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.15 — beta-Grasp (ubiquitin-like)
超家族 Superfamily superfamilyd.15.13 — Nqo1 middle domain-like
家族 Family familyd.15.13.0 — automated matches
结构域编号 domain_idd6zk913
类 Class classa — All alpha proteins
折叠类型 Fold folda.29 — Bromodomain-like
超家族 Superfamily superfamilya.29.12 — Nqo1C-terminal domain-like
家族 Family familya.29.12.0 — automated matches
结构域编号 domain_idd6zk94_
类 Class classe — Multi-domain proteins (alpha and beta)
折叠类型 Fold folde.18 — HydB/Nqo4-like
超家族 Superfamily superfamilye.18.1 — HydB/Nqo4-like
家族 Family familye.18.1.0 — automated matches
结构域编号 domain_idd6zk9g_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.71 — LYR proteins from mammalian respiratory complex I
超家族 Superfamily superfamilyf.71.1 — LYR protein-like
家族 Family familyf.71.1.1 — LYR proteins
结构域编号 domain_idd6zk9j_
类 Class classa — All alpha proteins
折叠类型 Fold folda.28 — Acyl carrier protein-like
超家族 Superfamily superfamilya.28.1 — ACP-like
家族 Family familya.28.1.0 — automated matches
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7. 引用文献 (1)