7a0l

Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Uricase

Aspergillus flavus

UniProt Q00511

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 4 8-AZAXANTHINE × 4 SODIUM ION × 4 water × 4 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name URIC_ASPFL
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–302; UniProt 1–302

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7a0l
Deposition date deposition_date2020-08-09
Structure title titleJoint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole
Keywords keywordsCOFACTOR-FREE OXIDASE, INHIBITOR, CATALYTIC WATER, DIOXYGEN BINDING, OXIDOREDUCTASE; OXIDOREDUCTASE
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7a0l__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7a0l__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7a0l__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)32.78 Å
Rg (electron density)30.72 Å
Total Rg32.38 Å
Atom count18780
Residues1180
Excluded volume219430 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7a0l__assembly_1__model_1 tetrameric (4) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd7a0la1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.96 — T-fold
Superfamily Superfamily superfamilyd.96.1 — Tetrahydrobiopterin biosynthesis enzymes-like
Family Family familyd.96.1.4 — Urate oxidase (uricase)
Domain ID domain_idd7a0la2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.96 — T-fold
Superfamily Superfamily superfamilyd.96.1 — Tetrahydrobiopterin biosynthesis enzymes-like
Family Family familyd.96.1.4 — Urate oxidase (uricase)
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7. Citations (1)