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7eca

Crystal structure of the Keap1 complex with a peptide base on ETGE motif.

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Kelch-like ECH-associated protein 1

Mus musculus

UniProt Q9Z2X8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 LEU-ASP-GLU-GLU-THR-GLY-GLU-PHE-LEU-PRO × 1 （Q60795） SULFATE ION × 11 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1x2j 4zy3 4zy3 5cgj 5fnq 5fnr 5fns 5fnt 5fnu 5fzj 5fzn 6qmc

62 assemblies; showing the first 12

Homodimer
9ujg 9uji 9uji 9uji 9uji 9ujj 9ujj 9ujj 9ujj

9 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1x2r 2dyh 2z32 3ade 3wdz 3wn7 3wn7 7eca 8in0 8q1q 8q1r

11 assemblies

View Construct and Data Evidence
UniProt name KEAP1_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 18–333； UniProt 309–624

LEU-ASP-GLU-GLU-THR-GLY-GLU-PHE-LEU-PRO

OrganismNot specified

UniProt Q60795

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Kelch-like ECH-associated protein 1 × 1 （Q9Z2X8） SULFATE ION × 11 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1x2r 2dyh 3wn7 3wn7 7eca

5 assemblies

View Construct and Data Evidence
UniProt name NF2L2_MOUSE
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–25； UniProt 65–89

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7eca
Deposition date deposition_date2021-03-11
Structure title titleCrystal structure of the Keap1 complex with a peptide base on ETGE motif.
Keywords keywordsNrf2, Oxidative stress, cancer, CYTOSOLIC PROTEIN; CYTOSOLIC PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7eca__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7eca__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7eca__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）18.93 Å
Rg (electron density)17.71 Å
Total Rg18.63 Å
Atom count2355
Residues300
Excluded volume40796 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7eca__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)