E3 ubiquitin-protein ligase TRIM21
Mus musculus
State in the Current Structure
| Assembly | Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Associated Components | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|
| 1 | Protein monomer Monomer Protein × 1 PDB declaration: monomeric（1） Consistent with protein copy count | Chain B； UniProt 291–470 | Not recorded | EDO 1,2-ETHANEDIOL × 2 WGM (3S)-1-(3-fluoropyridin-2-yl)-4,4-dimethylpyrrolidin-3-ol × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8 | Resolution 1.29 Å R-free 0.196 |
Other States of the Same Protein in the Database
Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.
| Other PDB | Difference from Current Entry 7HNA | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2VOK Murine TRIM21 Deposited 2008-02-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
291–470（180 aa）
Chain B
291–470（180 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.30 Å R-free 0.236 |
| 3ZO0 Mouse IgG2a in complex with mouse TRIM21 PRYSPRY Deposited 2013-02-19 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain B
291–470（180 aa）
Fragment：RESIDUES 291-470
|
Not recorded | MAN alpha-D-mannopyranose × 2 FUC alpha-L-fucopyranose × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.99 Å R-free 0.253 |
| 7HLA PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z111634612 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BE6 (8R)-2-methyl-5-(propan-2-yl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one × 2 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.23 Å R-free 0.190 |
| 7HLB PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z45705015 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | S9S ~{N}-[2-(4-fluorophenyl)ethyl]methanesulfonamide × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.21 Å R-free 0.197 |
| 7HLC PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1079512010 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 UWS 6-methyl-2-[(3-methyl-1,2-oxazol-5-yl)methyl]pyridazin-3(2H)-one × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.35 Å R-free 0.206 |
| 7HLD PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1401276297 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 U0S (5S)-7-(pyrazin-2-yl)-2-oxa-7-azaspiro[4.4]nonane × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.22 Å R-free 0.196 |
| 7HLE PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1696844792 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | UXG 1-(diphenylmethyl)azetidin-3-ol × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.40 Å R-free 0.209 |
| 7HLF PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z2092555279 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 A1BE7 (3R)-3-ethyl-1-(5-fluoropyridin-2-yl)pyrrolidin-3-ol × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.39 Å R-free 0.204 |
| 7HLG PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z2365130785 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 A1BE8 (1r,3r)-3-[(3-fluoropyridin-2-yl)amino]-1-methylcyclobutan-1-ol × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.50 Å R-free 0.208 |
| 7HLH PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z453319206 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 LWD ~{N}-quinolin-6-ylbenzamide × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.38 Å R-free 0.195 |
| 7HLI PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z2017861827 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BE9 1-[(1S,4S)-1,2,3,4-tetrahydro-1,4-(epiminomethano)naphthalen-10-yl]ethan-1-one × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.35 Å R-free 0.211 |
| 7HLJ PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1980894300 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 TU6 [4-methyl-6-(piperidin-1-yl)pyrimidin-2-yl]methanol × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.37 Å R-free 0.198 |
| 7HLK PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z285642082 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 UUP N-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.39 Å R-free 0.212 |
| 7HLL PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1328968520 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 J4Q 4-[(2-methylsulfonylimidazol-1-yl)methyl]-1,3-thiazole × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.188 |
| 7HLM PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z29077827 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | GTJ ~{N}-(1-propylbenzimidazol-2-yl)propanamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.192 |
| 7HLN PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z26823525 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1A4A (2S)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)oxolane-2-carboxamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.20 Å R-free 0.194 |
| 7HLO PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z90122368 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 A1BFA 4-acetylpiperazine-1-carboxamide × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.190 |
| 7HLP PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z29634868 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 A1BFB 2-oxo-4-propyl-2H-1-benzopyran-7-yl acetate × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.19 Å R-free 0.198 |
| 7HLQ PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z32327641 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 JMM [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl)methanone × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.33 Å R-free 0.200 |
| 7HLR PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1430613393 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 LKU 3-fluoro-N-(3-hydroxy-4-methylphenyl)benzamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.34 Å R-free 0.200 |
| 7HLS PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z29177127 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BFC 3-(2-methylpropanamido)benzamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.195 |
| 7HLT PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z328695024 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 K1G N,1-dimethyl-N-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine × 2 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.187 |
| 7HLU PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z741055844 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | S0V morpholin-4-yl(1,2,3-thiadiazol-4-yl)methanone × 2 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.187 |
| 7HLV PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z79432418 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BFD 2-(2-oxopyrrolidin-1-yl)-N-(1,3-thiazol-2-yl)acetamide × 2 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.19 Å R-free 0.197 |
| 7HLW PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z438096750 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFF N-{[(3S)-1-acetylpiperidin-3-yl]methyl}methanesulfonamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.40 Å R-free 0.216 |
| 7HLX PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z32367954 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 UXA ~{N}-cyclopropyl-1,3-benzodioxole-5-carboxamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.28 Å R-free 0.195 |
| 7HLY PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z235449082 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 JFS [4-(1H-benzimidazol-1-yl)phenyl]methanol × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.32 Å R-free 0.199 |
| 7HLZ PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z256709358 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 BP4 biphenyl-4-ylacetic acid × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.29 Å R-free 0.195 |
| 7HM0 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z374427992 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFG N-{[2-(dimethylamino)pyridin-4-yl]methyl}acetamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.43 Å R-free 0.214 |
| 7HM1 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z793778804 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | VWV ethyl (1,1-dioxo-1lambda~6~,4-thiazinan-4-yl)acetate × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.34 Å R-free 0.212 |
| 7HM2 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z32400357 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | NZJ 1-(3-methylbenzene-1-carbonyl)piperidine-4-carboxamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.200 |
| 7HM3 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1359419878 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 K6U (2M)-2-(2-methoxyphenyl)-1,3,4-oxadiazole × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.23 Å R-free 0.198 |
| 7HM4 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1407673036 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | VW4 (2S)-2-phenylpropane-1-sulfonamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.42 Å R-free 0.213 |
| 7HM5 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z192955056 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 Q4L methyl 4-(4-fluorophenyl)piperazine-1-carboxylate × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.38 Å R-free 0.202 |
| 7HM6 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1172243962 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BDJ 5-fluoro-N-(oxan-4-yl)pyridin-2-amine × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.33 Å R-free 0.197 |
| 7HM7 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1635496816 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BFH N-(6-methyl-2H-1,3-benzodioxol-5-yl)acetamide × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.34 Å R-free 0.193 |
| 7HM8 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z285782452 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 UVA N-methyl-2-(methylsulfonyl)aniline × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.33 Å R-free 0.199 |
| 7HM9 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1222331430 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFI N,N-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.25 Å R-free 0.200 |
| 7HMA PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z291279160 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 LV4 1-[2-(trifluoromethyloxy)phenyl]thiourea × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.189 |
| 7HMB PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1374778753 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | B1J [1-(4-chlorophenyl)-1,2,3-triazol-4-yl]methanol × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.36 Å R-free 0.207 |
| 7HMC PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1954800564 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 NZ1 5-methoxy-1,3-benzothiazol-2-amine × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.32 Å R-free 0.205 |
| 7HMD PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z425387594 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 H04 1-(2-ethoxyphenyl)piperazine × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.29 Å R-free 0.191 |
| 7HME PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z319545618 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 RXS 3-[(2-methyl-1H-imidazol-1-yl)methyl]benzonitrile × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.51 Å R-free 0.204 |
| 7HMF PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1367324110 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 RZJ 1-methyl-3,4-dihydro-2~{H}-quinoline-7-sulfonamide × 2 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.20 Å R-free 0.195 |
| 7HMG PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z274575916 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 WKS 2,4-dimethyl-6-(piperazin-1-yl)pyrimidine × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.32 Å R-free 0.184 |
| 7HMH PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1636723439 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BFJ (2R)-N-methylmorpholine-2-carboxamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.50 Å R-free 0.213 |
| 7HMI PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1742054999 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFK N,N-dimethyl-5-(piperidin-4-yl)-1,2,4-oxadiazol-3-amine × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.42 Å R-free 0.215 |
| 7HMJ PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1578665941 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | K1P 1-(3-methyl-1,2,4-thiadiazol-5-yl)-1,4-diazepane × 1 EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.50 Å R-free 0.214 |
| 7HMK PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z271004858 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SFY 4-amino-N-(pyridin-2-yl)benzenesulfonamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.35 Å R-free 0.209 |
| 7HML PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1354416068 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | X1J 1-(5-amino-1,3-dihydro-2H-isoindol-2-yl)ethan-1-one × 1 EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.26 Å R-free 0.201 |
| 7HMM PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z165170770 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | W0Y N-methyl-4-sulfamoylbenzamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.28 Å R-free 0.199 |
| 7HMN PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z57478994 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 UVS 5-(methoxymethyl)-1,3,4-thiadiazol-2-amine × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.33 Å R-free 0.202 |
| 7HMO PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z198194394 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 O1M 4-(4-fluorophenyl)piperazine-1-carboxamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.30 Å R-free 0.201 |
| 7HMP PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1530301542 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 ZQA 4-ethyl-2-(1H-imidazol-5-yl)-1,3-thiazole × 2 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.192 |
| 7HMQ PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1267773633 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1A36 1-(2-ethyl-1,3-thiazol-5-yl)-N-methylmethanamine × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.43 Å R-free 0.203 |
| 7HMR PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1267882044 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFL N-{[(2R)-oxolan-2-yl]methyl}pyridin-4-amine × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.192 |
| 7HMS PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z126932614 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | T6J 2-[(methylsulfonyl)methyl]-1H-benzimidazole × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.194 |
| 7HMT PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z2004563941 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFM (1R)-1-(1-cyclopentyl-1H-pyrazol-4-yl)ethan-1-ol × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.28 Å R-free 0.206 |
| 7HMU PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1741966151 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | W1A N-[(piperidin-4-yl)methyl]methanesulfonamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.189 |
| 7HMV PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z56978034 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | U2R (4-fluorophenoxy)acetic acid × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.194 |
| 7HMW PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1492796719 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | S7G ~{N}-[(3~{R})-1,2,3,4-tetrahydroquinolin-3-yl]ethanamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.34 Å R-free 0.207 |
| 7HMX PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z763030030 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 WJA N-methyl-1-(5-methyl-1,2-oxazol-3-yl)methanesulfonamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.57 Å R-free 0.239 |
| 7HMY PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z111782404 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 ZTQ (2S)-2-[([1,1'-biphenyl]-4-yl)oxy]propanoic acid × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.188 |
| 7HMZ PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z85893853 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BFN (3S)-1-[(4-fluorophenyl)acetyl]piperidine-3-carboxylic acid × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.28 Å R-free 0.199 |
| 7HN0 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1217960891 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | Q49 (3S)-3-(3-fluorophenoxy)-1-methylpyrrolidin-2-one × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.33 Å R-free 0.204 |
| 7HN1 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z2065616520 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BFO N-ethyl-1-(pyridin-4-yl)piperidin-4-amine × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.47 Å R-free 0.229 |
| 7HN2 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1002247062 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BFP N-{[(2R)-4-methylmorpholin-2-yl]methyl}-1,3-thiazol-2-amine × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.23 Å R-free 0.198 |
| 7HN3 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z2301438417 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BFQ 1,3-dimethyl-1H-pyrazolo[3,4-d]pyridazin-7-ol × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.28 Å R-free 0.198 |
| 7HN4 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z56827661 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 VZY N-(3-methylbenzene-1-carbonyl)glycine × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.19 Å R-free 0.195 |
| 7HN5 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z45617795 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | JFM N-(2-phenylethyl)methanesulfonamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.32 Å R-free 0.194 |
| 7HN6 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1998104358 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFR (5S)-N,N-dimethyl-2,9-dioxa-6-azaspiro[4.5]decane-6-carboxamide × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.40 Å R-free 0.212 |
| 7HN7 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z198194396 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 K2M 4-(furan-2-carbonyl)piperazine-1-carboxamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.31 Å R-free 0.203 |
| 7HN8 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1318110042 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFS 4-[(but-2-yn-1-yl)(methyl)amino]-1lambda~6~-thiane-1,1-dione × 2 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.23 Å R-free 0.197 |
| 7HN9 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1787761777 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFT (3S,4S)-3-methoxy-4-methyl-1-[(1,3-thiazol-5-yl)methyl]piperidine × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.22 Å R-free 0.195 |
| 7HNB PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z31478538 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | T9Q N-Benzyl-2-methoxyacetamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.52 Å R-free 0.208 |
| 7HNC PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z220996120 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | TV9 N-[(1S)-1-(pyridin-3-yl)ethyl]cyclopropanecarboxamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.203 |
| 7HND PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z52314092 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | U78 ~{N}-[2-(2-methylphenyl)ethyl]ethanamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.34 Å R-free 0.204 |
| 7HNE PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1343518214 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFU 1-(3-methoxyazetidine-1-sulfonyl)pyrrolidine × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.33 Å R-free 0.198 |
| 7HNF PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1689442171 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFV (5-fluoro-3,6-dihydropyridin-1(2H)-yl)(morpholin-4-yl)methanone × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.32 Å R-free 0.202 |
| 7HNG PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1568344634 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | O3D 4-[(furan-2-yl)methyl]-1lambda~6~,4-thiazinane-1,1-dione × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.34 Å R-free 0.202 |
| 7HNH PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z2643472210 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BFW 1-methyl-N-{[(2S)-oxolan-2-yl]methyl}-1H-pyrazole-3-carboxamide × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.34 Å R-free 0.194 |
| 7HNI PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z373768900 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 NUA N-(1-ethyl-1H-pyrazol-4-yl)cyclobutanecarboxamide × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.27 Å R-free 0.190 |
| 7HNJ PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1162778919 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1AP3 1-[(5-ethyl-1,2,4-oxadiazol-3-yl)methyl]pyridin-2(1H)-one × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.43 Å R-free 0.196 |
| 7HNK PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1275599911 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | WKG 1-(2-azaspiro[5.6]dodecan-2-yl)ethan-1-one × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.39 Å R-free 0.205 |
| 7HNL PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1251207602 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 RWS 1-(5-methyl-1,3,4-thiadiazol-2-yl)piperidine × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.44 Å R-free 0.216 |
| 7HNM PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z768399682 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFX [(2R,5S)-2,5-dimethylmorpholin-4-yl](1,2,5-thiadiazol-3-yl)methanone × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.49 Å R-free 0.209 |
| 7HNN PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z31432226 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | JGP (azepan-1-yl)(2H-1,3-benzodioxol-5-yl)methanone × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.31 Å R-free 0.202 |
| 7HNO PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z57450788 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 RV4 N-{4-[(morpholin-4-yl)methyl]phenyl}acetamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.33 Å R-free 0.189 |
| 7HNP PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z106579662 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 NUY [4-(propan-2-yl)piperazin-1-yl](thiophen-2-yl)methanone × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.30 Å R-free 0.199 |
| 7HNQ PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z30620520 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 GX4 cyclopropyl-[4-(4-fluorophenyl)piperazin-1-yl]methanone × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.37 Å R-free 0.196 |
| 7HNR PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1545312521 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | NTV (2S)-N-(3-chloro-2-methylphenyl)oxolane-2-carboxamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.30 Å R-free 0.202 |
| 7HNS PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z2072621991 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 LQP 2-(difluoromethoxy)-1-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]ethan-1-one × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.29 Å R-free 0.201 |
| 7HNT PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z383202616 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 LHR N-(1H-indazol-6-yl)acetamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.17 Å R-free 0.197 |
| 7HNU PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1614545742 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 GQJ methyl (2~{S},4~{R})-1-(furan-2-ylcarbonyl)-4-oxidanyl-pyrrolidine-2-carboxylate × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.202 |
| 7HNV PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z404993336 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 UUM 5-methyl-N-(1-methyl-1H-pyrazol-4-yl)-1,2-oxazole-3-carboxamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.34 Å R-free 0.191 |
| 7HNW PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1446981563 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BFY N-[(9S)-6-oxaspiro[4.5]decan-9-yl]methanesulfonamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.21 Å R-free 0.191 |
| 7HNX PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z133729708 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | WHP N-[(1R)-1-(2-chlorophenyl)ethyl]methanesulfonamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.27 Å R-free 0.196 |
| 7HNY PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z44592329 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 K0G N-phenyl-N'-pyridin-3-ylurea × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.28 Å R-free 0.193 |
| 7HNZ PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1245793018 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 JGD N,N-dimethylpyridin-4-amine × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.189 |
| 7HO0 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z363071686 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1A3S N-methyl-N-[2-oxo-2-(piperidin-1-yl)ethyl]methanesulfonamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.196 |
| 7HO1 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z369263636 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 A1BFZ N-[(1R)-1-(1,5-dimethyl-1H-pyrazol-4-yl)ethyl]methanesulfonamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.17 Å R-free 0.193 |
| 7HO2 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z730649594 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 NUM N-[2-(4-hydroxyphenyl)ethyl]pyridine-2-carboxamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.192 |
| 7HO3 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z405825414 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BF0 N-[(3S)-1-propanoylpiperidin-3-yl]methanesulfonamide × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.45 Å R-free 0.185 |
| 7HO4 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1003146540 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 LL0 2-(difluoromethoxy)benzene-1-sulfonamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.21 Å R-free 0.194 |
| 7HO5 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1266933824 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 UXD (1H-pyrazol-4-yl)(pyrrolidin-1-yl)methanone × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.18 Å R-free 0.196 |
| 7HO6 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z3220108246 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1BF1 4-benzylpiperazine-2,6-dione × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.24 Å R-free 0.192 |
| 7HO7 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z30820160 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 JFP N-(4-methyl-1,3-thiazol-2-yl)propanamide × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.30 Å R-free 0.204 |
| 7HO8 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z993967070 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | O1J (benzyloxy)acetic acid × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.39 Å R-free 0.197 |
| 7HO9 PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z1250132788 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | A1A3W (1R)-N-methyl-1-(pyridin-4-yl)propan-1-amine × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.26 Å R-free 0.199 |
| 7HOA PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z275165822 Deposited 2024-11-04 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 WNY 1-[4-(4-chlorophenyl)piperazin-1-yl]ethan-1-one × 1 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.35 Å R-free 0.201 |
| 7HOB PanDDA analysis group deposition -- Crystal Structure of TRIM21, ground state Deposited 2024-11-05 | Different ligand/ion Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；4 % PEG 400, 2 M AmmSO4, 0.1 M HEPES pH 8
|
Resolution 1.15 Å R-free 0.185 |
| 9GTE Crystal structure of TRIM21 PRY-SPRY domain bound to Suramin Deposited 2024-09-17 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
291–470（180 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 6 SVR 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；293 K；20% PEG 6.000
10% ethylene glycol
0.2 ammonium Chlorid
|
Resolution 1.30 Å R-free 0.179 |
112 other PDB entries and 112 assemblies. Open the comparison page and filter oligomeric states
View Construct and Data Evidence
| UniProt name | RO52_MOUSE |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain B； PDBConstruct 9–188； UniProt 291–470 |
