7rd1

The Capsid Structure of the ChAdOx1 viral vector/chimpanzee adenovirus Y25

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Pre-protein VI

Chimpanzee adenovirus Y25

UniProt G9G853

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 1920 Hexon protein × 720 (G9G854) Penton protein × 60 (G9G849) Hexon-interlacing protein × 240 (G9G843) Pre-hexon-linking protein IIIa × 60 (G9G848) Pre-hexon-linking protein VIII × 120 (G9G860) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 32 Hexon protein × 12 (G9G854) Penton protein × 1 (G9G849) Hexon-interlacing protein × 4 (G9G843) Pre-hexon-linking protein IIIa × 1 (G9G848) Pre-hexon-linking protein VIII × 2 (G9G860) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 160 Hexon protein × 60 (G9G854) Penton protein × 5 (G9G849) Hexon-interlacing protein × 20 (G9G843) Pre-hexon-linking protein IIIa × 5 (G9G848) Pre-hexon-linking protein VIII × 10 (G9G860) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 192 Hexon protein × 72 (G9G854) Penton protein × 6 (G9G849) Hexon-interlacing protein × 24 (G9G843) Pre-hexon-linking protein IIIa × 6 (G9G848) Pre-hexon-linking protein VIII × 12 (G9G860) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 32 Hexon protein × 12 (G9G854) Penton protein × 1 (G9G849) Hexon-interlacing protein × 4 (G9G843) Pre-hexon-linking protein IIIa × 1 (G9G848) Pre-hexon-linking protein VIII × 2 (G9G860) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name G9G853_9ADEN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain 0; PDBConstruct 1–243; UniProt 1–243 Author chain 1; PDBConstruct 1–243; UniProt 1–243 Author chain 2; PDBConstruct 1–243; UniProt 1–243 Author chain 3; PDBConstruct 1–243; UniProt 1–243 Author chain 4; PDBConstruct 1–243; UniProt 1–243 Author chain 8; PDBConstruct 1–243; UniProt 1–243 Author chain U; PDBConstruct 1–243; UniProt 1–243 Author chain V; PDBConstruct 1–243; UniProt 1–243 Author chain W; PDBConstruct 1–243; UniProt 1–243 Author chain X; PDBConstruct 1–243; UniProt 1–243 Author chain Y; PDBConstruct 1–243; UniProt 1–243 Author chain Z; PDBConstruct 1–243; UniProt 1–243

Hexon protein

Chimpanzee adenovirus Y25

UniProt G9G854

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 1920 Pre-protein VI × 720 (G9G853) Penton protein × 60 (G9G849) Hexon-interlacing protein × 240 (G9G843) Pre-hexon-linking protein IIIa × 60 (G9G848) Pre-hexon-linking protein VIII × 120 (G9G860) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 32 Pre-protein VI × 12 (G9G853) Penton protein × 1 (G9G849) Hexon-interlacing protein × 4 (G9G843) Pre-hexon-linking protein IIIa × 1 (G9G848) Pre-hexon-linking protein VIII × 2 (G9G860) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 160 Pre-protein VI × 60 (G9G853) Penton protein × 5 (G9G849) Hexon-interlacing protein × 20 (G9G843) Pre-hexon-linking protein IIIa × 5 (G9G848) Pre-hexon-linking protein VIII × 10 (G9G860) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 192 Pre-protein VI × 72 (G9G853) Penton protein × 6 (G9G849) Hexon-interlacing protein × 24 (G9G843) Pre-hexon-linking protein IIIa × 6 (G9G848) Pre-hexon-linking protein VIII × 12 (G9G860) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 32 Pre-protein VI × 12 (G9G853) Penton protein × 1 (G9G849) Hexon-interlacing protein × 4 (G9G843) Pre-hexon-linking protein IIIa × 1 (G9G848) Pre-hexon-linking protein VIII × 2 (G9G860) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name G9G854_9ADEN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain A; PDBConstruct 1–942; UniProt 1–942 Author chain B; PDBConstruct 1–942; UniProt 1–942 Author chain C; PDBConstruct 1–942; UniProt 1–942 Author chain D; PDBConstruct 1–942; UniProt 1–942 Author chain E; PDBConstruct 1–942; UniProt 1–942 Author chain F; PDBConstruct 1–942; UniProt 1–942 Author chain G; PDBConstruct 1–942; UniProt 1–942 Author chain H; PDBConstruct 1–942; UniProt 1–942 Author chain I; PDBConstruct 1–942; UniProt 1–942 Author chain J; PDBConstruct 1–942; UniProt 1–942 Author chain K; PDBConstruct 1–942; UniProt 1–942 Author chain L; PDBConstruct 1–942; UniProt 1–942

Penton protein

Chimpanzee adenovirus Y25

UniProt G9G849

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 1920 Pre-protein VI × 720 (G9G853) Hexon protein × 720 (G9G854) Hexon-interlacing protein × 240 (G9G843) Pre-hexon-linking protein IIIa × 60 (G9G848) Pre-hexon-linking protein VIII × 120 (G9G860) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 32 Pre-protein VI × 12 (G9G853) Hexon protein × 12 (G9G854) Hexon-interlacing protein × 4 (G9G843) Pre-hexon-linking protein IIIa × 1 (G9G848) Pre-hexon-linking protein VIII × 2 (G9G860) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 160 Pre-protein VI × 60 (G9G853) Hexon protein × 60 (G9G854) Hexon-interlacing protein × 20 (G9G843) Pre-hexon-linking protein IIIa × 5 (G9G848) Pre-hexon-linking protein VIII × 10 (G9G860) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 192 Pre-protein VI × 72 (G9G853) Hexon protein × 72 (G9G854) Hexon-interlacing protein × 24 (G9G843) Pre-hexon-linking protein IIIa × 6 (G9G848) Pre-hexon-linking protein VIII × 12 (G9G860) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 32 Pre-protein VI × 12 (G9G853) Hexon protein × 12 (G9G854) Hexon-interlacing protein × 4 (G9G843) Pre-hexon-linking protein IIIa × 1 (G9G848) Pre-hexon-linking protein VIII × 2 (G9G860) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name G9G849_9ADEN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain M; PDBConstruct 1–532; UniProt 1–532

Hexon-interlacing protein

Chimpanzee adenovirus Y25

UniProt G9G843

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 1920 Pre-protein VI × 720 (G9G853) Hexon protein × 720 (G9G854) Penton protein × 60 (G9G849) Pre-hexon-linking protein IIIa × 60 (G9G848) Pre-hexon-linking protein VIII × 120 (G9G860) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 32 Pre-protein VI × 12 (G9G853) Hexon protein × 12 (G9G854) Penton protein × 1 (G9G849) Pre-hexon-linking protein IIIa × 1 (G9G848) Pre-hexon-linking protein VIII × 2 (G9G860) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 160 Pre-protein VI × 60 (G9G853) Hexon protein × 60 (G9G854) Penton protein × 5 (G9G849) Pre-hexon-linking protein IIIa × 5 (G9G848) Pre-hexon-linking protein VIII × 10 (G9G860) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 192 Pre-protein VI × 72 (G9G853) Hexon protein × 72 (G9G854) Penton protein × 6 (G9G849) Pre-hexon-linking protein IIIa × 6 (G9G848) Pre-hexon-linking protein VIII × 12 (G9G860) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 32 Pre-protein VI × 12 (G9G853) Hexon protein × 12 (G9G854) Penton protein × 1 (G9G849) Pre-hexon-linking protein IIIa × 1 (G9G848) Pre-hexon-linking protein VIII × 2 (G9G860) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name G9G843_9ADEN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain N; PDBConstruct 1–142; UniProt 1–142 Author chain O; PDBConstruct 1–142; UniProt 1–142 Author chain P; PDBConstruct 1–142; UniProt 1–142 Author chain Q; PDBConstruct 1–142; UniProt 1–142

Pre-hexon-linking protein IIIa

Chimpanzee adenovirus Y25

UniProt G9G848

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 1920 Pre-protein VI × 720 (G9G853) Hexon protein × 720 (G9G854) Penton protein × 60 (G9G849) Hexon-interlacing protein × 240 (G9G843) Pre-hexon-linking protein VIII × 120 (G9G860) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 32 Pre-protein VI × 12 (G9G853) Hexon protein × 12 (G9G854) Penton protein × 1 (G9G849) Hexon-interlacing protein × 4 (G9G843) Pre-hexon-linking protein VIII × 2 (G9G860) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 160 Pre-protein VI × 60 (G9G853) Hexon protein × 60 (G9G854) Penton protein × 5 (G9G849) Hexon-interlacing protein × 20 (G9G843) Pre-hexon-linking protein VIII × 10 (G9G860) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 192 Pre-protein VI × 72 (G9G853) Hexon protein × 72 (G9G854) Penton protein × 6 (G9G849) Hexon-interlacing protein × 24 (G9G843) Pre-hexon-linking protein VIII × 12 (G9G860) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 32 Pre-protein VI × 12 (G9G853) Hexon protein × 12 (G9G854) Penton protein × 1 (G9G849) Hexon-interlacing protein × 4 (G9G843) Pre-hexon-linking protein VIII × 2 (G9G860) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name G9G848_9ADEN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain R; PDBConstruct 1–589; UniProt 1–589

Pre-hexon-linking protein VIII

Chimpanzee adenovirus Y25

UniProt G9G860

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 1920 Pre-protein VI × 720 (G9G853) Hexon protein × 720 (G9G854) Penton protein × 60 (G9G849) Hexon-interlacing protein × 240 (G9G843) Pre-hexon-linking protein IIIa × 60 (G9G848) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 32 Pre-protein VI × 12 (G9G853) Hexon protein × 12 (G9G854) Penton protein × 1 (G9G849) Hexon-interlacing protein × 4 (G9G843) Pre-hexon-linking protein IIIa × 1 (G9G848) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 160 Pre-protein VI × 60 (G9G853) Hexon protein × 60 (G9G854) Penton protein × 5 (G9G849) Hexon-interlacing protein × 20 (G9G843) Pre-hexon-linking protein IIIa × 5 (G9G848) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 192 Pre-protein VI × 72 (G9G853) Hexon protein × 72 (G9G854) Penton protein × 6 (G9G849) Hexon-interlacing protein × 24 (G9G843) Pre-hexon-linking protein IIIa × 6 (G9G848) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 32 Pre-protein VI × 12 (G9G853) Hexon protein × 12 (G9G854) Penton protein × 1 (G9G849) Hexon-interlacing protein × 4 (G9G843) Pre-hexon-linking protein IIIa × 1 (G9G848) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name G9G860_9ADEN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain S; PDBConstruct 1–227; UniProt 1–227 Author chain T; PDBConstruct 1–227; UniProt 1–227

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7rd1
Deposition date deposition_date2021-07-08
Structure title titleThe Capsid Structure of the ChAdOx1 viral vector/chimpanzee adenovirus Y25
Keywords keywords;Adenovirus, simian adenovirus, chimpanzee adenovirus, vaccine vector, DNA virus, AdV, ChAdV-Y25, adenovirus Y25, Y25, viral vector, ChAdOx1, chimp Ad, dsDNA virus, icosahedral, chimpanzee adenovirus Y25, Y-25, Y 25, ChAdV, VIRUS ;; VIRUS
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7rd1__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7rd1__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 1012 1013 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7rd1__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)0.00 Å
Rg (electron density)379.20 Å
Total Rg379.20 Å
Atom count11866920
Residues766380
Excluded volume106980000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7rd1__assembly_1__model_1 1920-meric (1920) Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7rd1__assembly_2__model_1 32-meric (32) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 7rd1__assembly_3__model_1 160-meric (160) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 7rd1__assembly_4__model_1 192-meric (192) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 7rd1__assembly_5__model_1 32-meric (32) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (2)