7tb3

cryo-EM structure of MBP-KIX-apoferritin

Method: ELECTRON MICROSCOPY
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed

Homo sapiens

UniProt P09528

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 同源多聚体 蛋白 24 无其他共同聚合物 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 FRIH_MOUSE
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 85–260; UniProt 7–182 作者链 B; PDB构建体 85–260; UniProt 7–182 作者链 C; PDB构建体 85–260; UniProt 7–182 作者链 D; PDB构建体 85–260; UniProt 7–182 作者链 E; PDB构建体 85–260; UniProt 7–182 作者链 F; PDB构建体 85–260; UniProt 7–182 作者链 G; PDB构建体 85–260; UniProt 7–182 作者链 H; PDB构建体 85–260; UniProt 7–182 作者链 I; PDB构建体 85–260; UniProt 7–182 作者链 J; PDB构建体 85–260; UniProt 7–182 作者链 K; PDB构建体 85–260; UniProt 7–182 作者链 L; PDB构建体 85–260; UniProt 7–182 作者链 M; PDB构建体 85–260; UniProt 7–182 作者链 N; PDB构建体 85–260; UniProt 7–182 作者链 O; PDB构建体 85–260; UniProt 7–182 作者链 P; PDB构建体 85–260; UniProt 7–182 作者链 Q; PDB构建体 85–260; UniProt 7–182 作者链 R; PDB构建体 85–260; UniProt 7–182 作者链 S; PDB构建体 85–260; UniProt 7–182 作者链 T; PDB构建体 85–260; UniProt 7–182 作者链 U; PDB构建体 85–260; UniProt 7–182 作者链 V; PDB构建体 85–260; UniProt 7–182 作者链 W; PDB构建体 85–260; UniProt 7–182 作者链 X; PDB构建体 85–260; UniProt 7–182

Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed

Homo sapiens

UniProt Q92793

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 同源多聚体 蛋白 24 无其他共同聚合物 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 CBP_HUMAN
Isoform Q92793-2
PDB实体 1
链与序列区间 作者链 A; PDB构建体 3–84; UniProt 549–630 作者链 B; PDB构建体 3–84; UniProt 549–630 作者链 C; PDB构建体 3–84; UniProt 549–630 作者链 D; PDB构建体 3–84; UniProt 549–630 作者链 E; PDB构建体 3–84; UniProt 549–630 作者链 F; PDB构建体 3–84; UniProt 549–630 作者链 G; PDB构建体 3–84; UniProt 549–630 作者链 H; PDB构建体 3–84; UniProt 549–630 作者链 I; PDB构建体 3–84; UniProt 549–630 作者链 J; PDB构建体 3–84; UniProt 549–630 作者链 K; PDB构建体 3–84; UniProt 549–630 作者链 L; PDB构建体 3–84; UniProt 549–630 作者链 M; PDB构建体 3–84; UniProt 549–630 作者链 N; PDB构建体 3–84; UniProt 549–630 作者链 O; PDB构建体 3–84; UniProt 549–630 作者链 P; PDB构建体 3–84; UniProt 549–630 作者链 Q; PDB构建体 3–84; UniProt 549–630 作者链 R; PDB构建体 3–84; UniProt 549–630 作者链 S; PDB构建体 3–84; UniProt 549–630 作者链 T; PDB构建体 3–84; UniProt 549–630 作者链 U; PDB构建体 3–84; UniProt 549–630 作者链 V; PDB构建体 3–84; UniProt 549–630 作者链 W; PDB构建体 3–84; UniProt 549–630 作者链 X; PDB构建体 3–84; UniProt 549–630

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id7tb3
沉积日期 deposition_date2021-12-21
结构标题 titlecryo-EM structure of MBP-KIX-apoferritin
关键词 keywordsProtein Engineering, Simulation, Peptide Therapeutics, Acute Myeloid Leukemia, STRUCTURAL PROTEIN; STRUCTURAL PROTEIN
实验方法 methodELECTRON MICROSCOPY
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

7tb3__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

7tb3__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

7tb3__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)61.39 Å
Rg(电子密度)60.49 Å
总 Rg60.81 Å
原子数47808
残基数5832
排除体积845070 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 7tb3__assembly_1__model_1 24-meric (24) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (1)

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6. 折叠分类 (SCOP + CATH) 32 domains

CATH v4.4 (32 domains)

结构域编号 domain_id7tb3A01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology246 — Serum Albumin; Chain A, Domain 1
同源超家族 H-superfamily homologous superfamily20 — Coactivator CBP, KIX domain
结构域编号 domain_id7tb3A02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3B01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3C01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3D01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3E01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3F01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3G01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology246 — Serum Albumin; Chain A, Domain 1
同源超家族 H-superfamily homologous superfamily20 — Coactivator CBP, KIX domain
结构域编号 domain_id7tb3G02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3H01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3I01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology246 — Serum Albumin; Chain A, Domain 1
同源超家族 H-superfamily homologous superfamily20 — Coactivator CBP, KIX domain
结构域编号 domain_id7tb3I02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3J01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology246 — Serum Albumin; Chain A, Domain 1
同源超家族 H-superfamily homologous superfamily20 — Coactivator CBP, KIX domain
结构域编号 domain_id7tb3J02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3K01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3L01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology246 — Serum Albumin; Chain A, Domain 1
同源超家族 H-superfamily homologous superfamily20 — Coactivator CBP, KIX domain
结构域编号 domain_id7tb3L02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3M01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3N01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology246 — Serum Albumin; Chain A, Domain 1
同源超家族 H-superfamily homologous superfamily20 — Coactivator CBP, KIX domain
结构域编号 domain_id7tb3N02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3O01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology246 — Serum Albumin; Chain A, Domain 1
同源超家族 H-superfamily homologous superfamily20 — Coactivator CBP, KIX domain
结构域编号 domain_id7tb3O02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3P01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3Q01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology246 — Serum Albumin; Chain A, Domain 1
同源超家族 H-superfamily homologous superfamily20 — Coactivator CBP, KIX domain
结构域编号 domain_id7tb3Q02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3R01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3S01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3T01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3U01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3V01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3W01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
结构域编号 domain_id7tb3X01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1260 — Ferritin
同源超家族 H-superfamily homologous superfamily10 — Ferritin, core subunit, four-helix bundle
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