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7tit

Cardiac thin filament decorated with regulatory M-domain of cardiac myosin binding protein C

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

cardiac actin

OrganismNot specified

UniProt A0A4X1UMF3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 Myosin-binding protein C, cardiac-type × 6 （Q14896） tropomyosin model × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7tij 7tit 7tj7

3 assemblies

View Construct and Data Evidence
UniProt name A0A4X1UMF3_PIG
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–375； UniProt 57–431 Author chain B； PDBConstruct 1–375； UniProt 57–431 Author chain C； PDBConstruct 1–375； UniProt 57–431 Author chain D； PDBConstruct 1–375； UniProt 57–431 Author chain E； PDBConstruct 1–375； UniProt 57–431 Author chain F； PDBConstruct 1–375； UniProt 57–431

Myosin-binding protein C, cardiac-type

Homo sapiens

UniProt Q14896

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 cardiac actin × 6 （A0A4X1UMF3） tropomyosin model × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1gxe 1pd6 2avg 2k1m 2mq0 2mq3 3cx2 5k6p

8 assemblies

Homodimer
2v6h

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6cxi 6cxj 6g2t 7lrg 7tij 7tit 7tj7 8g4l

8 assemblies

View Construct and Data Evidence
UniProt name MYPC3_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain G； PDBConstruct 1–220； UniProt 151–370 Author chain H； PDBConstruct 1–220； UniProt 151–370 Author chain I； PDBConstruct 1–220； UniProt 151–370 Author chain J； PDBConstruct 1–220； UniProt 151–370 Author chain K； PDBConstruct 1–220； UniProt 151–370 Author chain L； PDBConstruct 1–220； UniProt 151–370

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7tit
Deposition date deposition_date2022-01-14
Structure title titleCardiac thin filament decorated with regulatory M-domain of cardiac myosin binding protein C
Keywords keywordscardiac contraction regulator, muscle protein, MOTOR PROTEIN; MOTOR PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7tit__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7tit__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7tit__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）56.63 Å
Rg (electron density)56.97 Å
Total Rg56.71 Å
Atom count24141
Residues3024
Excluded volume392600 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7tit__assembly_1__model_1 hexadecameric （16） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)