SAXSdb — 8g4l

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Myosin-7

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 123	Myosin light chain 3 × 18 （P08590） Myosin regulatory light chain 2, ventricular/cardiac muscle isoform × 18 （P10916） Titin × 6 （Q8WZ42） Myosin-binding protein C, cardiac-type × 3 （Q14896）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MYH7_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–1935； UniProt 1–1935 Author chain AA； PDBConstruct 1–1935； UniProt 1–1935 Author chain AB； PDBConstruct 1–1935； UniProt 1–1935 Author chain AG； PDBConstruct 1–1935； UniProt 1–1935 Author chain AH； PDBConstruct 1–1935； UniProt 1–1935 Author chain AI； PDBConstruct 1–1935； UniProt 1–1935 Author chain AJ； PDBConstruct 1–1935； UniProt 1–1935 Author chain AK； PDBConstruct 1–1935； UniProt 1–1935 Author chain AL； PDBConstruct 1–1935； UniProt 1–1935 Author chain AM； PDBConstruct 1–1935； UniProt 1–1935 Author chain AN； PDBConstruct 1–1935； UniProt 1–1935 Author chain AO； PDBConstruct 1–1935； UniProt 1–1935 Author chain AP； PDBConstruct 1–1935； UniProt 1–1935 Author chain AQ； PDBConstruct 1–1935； UniProt 1–1935 Author chain AR； PDBConstruct 1–1935； UniProt 1–1935 Author chain AS； PDBConstruct 1–1935； UniProt 1–1935 Author chain AT； PDBConstruct 1–1935； UniProt 1–1935 Author chain AU； PDBConstruct 1–1935； UniProt 1–1935 Author chain AV； PDBConstruct 1–1935； UniProt 1–1935 Author chain AW； PDBConstruct 1–1935； UniProt 1–1935 Author chain AX； PDBConstruct 1–1935； UniProt 1–1935 Author chain AY； PDBConstruct 1–1935； UniProt 1–1935 Author chain AZ； PDBConstruct 1–1935； UniProt 1–1935 Author chain B； PDBConstruct 1–1935； UniProt 1–1935 Author chain BA； PDBConstruct 1–1935； UniProt 1–1935 Author chain BB； PDBConstruct 1–1935； UniProt 1–1935 Author chain BG； PDBConstruct 1–1935； UniProt 1–1935 Author chain BH； PDBConstruct 1–1935； UniProt 1–1935 Author chain BI； PDBConstruct 1–1935； UniProt 1–1935 Author chain BJ； PDBConstruct 1–1935； UniProt 1–1935 Author chain BK； PDBConstruct 1–1935； UniProt 1–1935 Author chain BL； PDBConstruct 1–1935； UniProt 1–1935 Author chain BM； PDBConstruct 1–1935； UniProt 1–1935 Author chain BN； PDBConstruct 1–1935； UniProt 1–1935 Author chain BO； PDBConstruct 1–1935； UniProt 1–1935 Author chain BP； PDBConstruct 1–1935； UniProt 1–1935 Author chain BQ； PDBConstruct 1–1935； UniProt 1–1935 Author chain BR； PDBConstruct 1–1935； UniProt 1–1935 Author chain BS； PDBConstruct 1–1935； UniProt 1–1935 Author chain BT； PDBConstruct 1–1935； UniProt 1–1935 Author chain BU； PDBConstruct 1–1935； UniProt 1–1935 Author chain BV； PDBConstruct 1–1935； UniProt 1–1935 Author chain BW； PDBConstruct 1–1935； UniProt 1–1935 Author chain BX； PDBConstruct 1–1935； UniProt 1–1935 Author chain BY； PDBConstruct 1–1935； UniProt 1–1935 Author chain BZ； PDBConstruct 1–1935； UniProt 1–1935 Author chain G； PDBConstruct 1–1935； UniProt 1–1935 Author chain H； PDBConstruct 1–1935； UniProt 1–1935 Author chain I； PDBConstruct 1–1935； UniProt 1–1935 Author chain J； PDBConstruct 1–1935； UniProt 1–1935 Author chain K； PDBConstruct 1–1935； UniProt 1–1935 Author chain L； PDBConstruct 1–1935； UniProt 1–1935 Author chain M； PDBConstruct 1–1935； UniProt 1–1935 Author chain N； PDBConstruct 1–1935； UniProt 1–1935 Author chain O； PDBConstruct 1–1935； UniProt 1–1935 Author chain P； PDBConstruct 1–1935； UniProt 1–1935 Author chain Q； PDBConstruct 1–1935； UniProt 1–1935 Author chain R； PDBConstruct 1–1935； UniProt 1–1935 Author chain S； PDBConstruct 1–1935； UniProt 1–1935 Author chain T； PDBConstruct 1–1935； UniProt 1–1935 Author chain U； PDBConstruct 1–1935； UniProt 1–1935 Author chain V； PDBConstruct 1–1935； UniProt 1–1935 Author chain W； PDBConstruct 1–1935； UniProt 1–1935 Author chain X； PDBConstruct 1–1935； UniProt 1–1935 Author chain Y； PDBConstruct 1–1935； UniProt 1–1935 Author chain Z； PDBConstruct 1–1935； UniProt 1–1935 Author chain ae； PDBConstruct 1–1935； UniProt 1–1935 Author chain af； PDBConstruct 1–1935； UniProt 1–1935 Author chain ak； PDBConstruct 1–1935； UniProt 1–1935 Author chain al； PDBConstruct 1–1935； UniProt 1–1935 Author chain be； PDBConstruct 1–1935； UniProt 1–1935 Author chain bf； PDBConstruct 1–1935； UniProt 1–1935 Author chain bk； PDBConstruct 1–1935； UniProt 1–1935 Author chain bl； PDBConstruct 1–1935； UniProt 1–1935 Author chain e； PDBConstruct 1–1935； UniProt 1–1935 Author chain f； PDBConstruct 1–1935； UniProt 1–1935 Author chain k； PDBConstruct 1–1935； UniProt 1–1935 Author chain l； PDBConstruct 1–1935； UniProt 1–1935

Myosin light chain 3

OrganismNot specified

UniProt P08590

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 123	Myosin-7 × 78 （P12883） Myosin regulatory light chain 2, ventricular/cardiac muscle isoform × 18 （P10916） Titin × 6 （Q8WZ42） Myosin-binding protein C, cardiac-type × 3 （Q14896）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MYL3_HUMAN
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain AE； PDBConstruct 1–195； UniProt 1–195 Author chain AF； PDBConstruct 1–195； UniProt 1–195 Author chain BE； PDBConstruct 1–195； UniProt 1–195 Author chain BF； PDBConstruct 1–195； UniProt 1–195 Author chain E； PDBConstruct 1–195； UniProt 1–195 Author chain F； PDBConstruct 1–195； UniProt 1–195 Author chain a； PDBConstruct 1–195； UniProt 1–195 Author chain aa； PDBConstruct 1–195； UniProt 1–195 Author chain ab； PDBConstruct 1–195； UniProt 1–195 Author chain ag； PDBConstruct 1–195； UniProt 1–195 Author chain ah； PDBConstruct 1–195； UniProt 1–195 Author chain b； PDBConstruct 1–195； UniProt 1–195 Author chain ba； PDBConstruct 1–195； UniProt 1–195 Author chain bb； PDBConstruct 1–195； UniProt 1–195 Author chain bg； PDBConstruct 1–195； UniProt 1–195 Author chain bh； PDBConstruct 1–195； UniProt 1–195 Author chain g； PDBConstruct 1–195； UniProt 1–195 Author chain h； PDBConstruct 1–195； UniProt 1–195

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

OrganismNot specified

UniProt P10916

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 123	Myosin-7 × 78 （P12883） Myosin light chain 3 × 18 （P08590） Titin × 6 （Q8WZ42） Myosin-binding protein C, cardiac-type × 3 （Q14896）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MLRV_HUMAN
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain ac； PDBConstruct 1–166； UniProt 1–166 Author chain ad； PDBConstruct 1–166； UniProt 1–166 Author chain ai； PDBConstruct 1–166； UniProt 1–166 Author chain aj； PDBConstruct 1–166； UniProt 1–166 Author chain aq； PDBConstruct 1–166； UniProt 1–166 Author chain ar； PDBConstruct 1–166； UniProt 1–166 Author chain bc； PDBConstruct 1–166； UniProt 1–166 Author chain bd； PDBConstruct 1–166； UniProt 1–166 Author chain bi； PDBConstruct 1–166； UniProt 1–166 Author chain bj； PDBConstruct 1–166； UniProt 1–166 Author chain bq； PDBConstruct 1–166； UniProt 1–166 Author chain br； PDBConstruct 1–166； UniProt 1–166 Author chain c； PDBConstruct 1–166； UniProt 1–166 Author chain d； PDBConstruct 1–166； UniProt 1–166 Author chain i； PDBConstruct 1–166； UniProt 1–166 Author chain j； PDBConstruct 1–166； UniProt 1–166 Author chain q； PDBConstruct 1–166； UniProt 1–166 Author chain r； PDBConstruct 1–166； UniProt 1–166

Titin

OrganismNot specified

UniProt Q8WZ42

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 123	Myosin-7 × 78 （P12883） Myosin light chain 3 × 18 （P08590） Myosin regulatory light chain 2, ventricular/cardiac muscle isoform × 18 （P10916） Myosin-binding protein C, cardiac-type × 3 （Q14896）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TITIN_HUMAN
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain am； PDBConstruct 1–1084； UniProt 22784–23867 Author chain an； PDBConstruct 1–1084； UniProt 22784–23867 Author chain bm； PDBConstruct 1–1084； UniProt 22784–23867 Author chain bn； PDBConstruct 1–1084； UniProt 22784–23867 Author chain m； PDBConstruct 1–1084； UniProt 22784–23867 Author chain n； PDBConstruct 1–1084； UniProt 22784–23867

Myosin-binding protein C, cardiac-type

OrganismNot specified

UniProt Q14896

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 123	Myosin-7 × 78 （P12883） Myosin light chain 3 × 18 （P08590） Myosin regulatory light chain 2, ventricular/cardiac muscle isoform × 18 （P10916） Titin × 6 （Q8WZ42）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MYPC3_HUMAN
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain ao； PDBConstruct 1–1274； UniProt 1–1274 Author chain bo； PDBConstruct 1–1274； UniProt 1–1274 Author chain o； PDBConstruct 1–1274； UniProt 1–1274

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	8g4l
Deposition date deposition_date	2023-02-10
Structure title title	Cryo-EM structure of the human cardiac myosin filament
Keywords keywords	cardiac, myosin, filament, complex, CONTRACTILE PROTEIN; CONTRACTILE PROTEIN
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8g4l__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8g4l__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

8g4l__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	0.00 Å
Rg (electron density)	167.90 Å
Total Rg	167.90 Å
Atom count	828952
Residues	51438
Excluded volume	7344000 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`8g4l__assembly_1__model_1`	123-meric （123）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

Entity 1 Entity 1 polymer

Description description	Myosin-7
Molecular weight formula_weight	223446.0 kDa
Source method src_method	nat
Copy count entity_count	78

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	;BB,BA,BG,BH,BI,BJ,BK,BL,BM,BN,BO,BP,BQ,BR,BS,BT,BU,BV,BW,BX,BY,BZ,be,bf,bk,bl,AA,AB,AG,AH,AI,AJ,AK,AL,AM,AN,AO,AP,AQ,AR,AS,AT,AU,AV,AW,AX,AY,AZ,ae,af,ak,al,A,B,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,e,f,k,l ;
Atom count atom_count	828952

MGDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGLNEE

Entity 2 Entity 2 polymer

Description description	Myosin light chain 3
Molecular weight formula_weight	21962.1 kDa
Source method src_method	nat
Copy count entity_count	18

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	BE,BF,ba,bb,bg,bh,AE,AF,aa,ab,ag,ah,E,F,a,b,g,h

MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS

Entity 3 Entity 3 polymer

Description description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
Molecular weight formula_weight	18813.3 kDa
Source method src_method	nat
Copy count entity_count	18

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	bc,bd,bi,bj,bq,br,ac,ad,ai,aj,aq,ar,c,d,i,j,q,r

MAPKKAKKRAGGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD

Entity 4 Entity 4 polymer

Description description	Titin
Molecular weight formula_weight	119772.0 kDa
EC 编号 ec_number	2.7.11.1
Source method src_method	nat
Copy count entity_count	6

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	bm,bn,am,an,m,n

PPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAP

Entity 5 Entity 5 polymer

Description description	Myosin-binding protein C, cardiac-type
Molecular weight formula_weight	140947.2 kDa
Source method src_method	nat
Copy count entity_count	3

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	bo,ao,o

MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	triclinic

Resolution resolution	6.40 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	102581

Cryo-EM structure of the human cardiac myosin filament

1. Protein Identity and Related Structures Protein Identity & Related Structures

Myosin-7

State in the Current Structure

Other States of the Same Protein in the Database

Myosin light chain 3

State in the Current Structure

Other States of the Same Protein in the Database

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

State in the Current Structure

Other States of the Same Protein in the Database

Titin

State in the Current Structure

Other States of the Same Protein in the Database

Myosin-binding protein C, cardiac-type

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

8g4l__assembly_1__model_1

8g4l__assembly_1__model_1 | I(q)

8g4l__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (5)

Entity 1 Entity 1 polymer

Polymer Polymer

Entity 2 Entity 2 polymer

Polymer Polymer

Entity 3 Entity 3 polymer

Polymer Polymer

Entity 4 Entity 4 polymer

Polymer Polymer

Entity 5 Entity 5 polymer

Polymer Polymer

7. Citations (1)

Cryo-EM structure of the human cardiac myosin filament

1. Protein Identity and Related Structures Protein Identity & Related Structures

Myosin-7

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Myosin light chain 3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Titin

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Myosin-binding protein C, cardiac-type

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

8g4l__assembly_1__model_1

8g4l__assembly_1__model_1 | I(q)

8g4l__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (5)

Entity 1 Entity 1 polymer

Polymer Polymer

Entity 2 Entity 2 polymer

Polymer Polymer

Entity 3 Entity 3 polymer

Polymer Polymer

Entity 4 Entity 4 polymer

Polymer Polymer

Entity 5 Entity 5 polymer

Polymer Polymer

7. Citations (1)