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8efd

Human cardiac myosin II and associated essential light chain in the rigor conformation

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Beta-cardiac myosin II

Homo sapiens

UniProt P12883

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Myosin light chain 1/3, skeletal muscle isoform × 1 （P05977） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
4db1 4db1 9gz2 9gz3 9htf 9htg 9i8p

7 assemblies

Homodimer
2fxm 2fxo 2fxo 4db1

4 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3dtp 3dtp 3dtp 4p7h 4p7h 4pa0 4pa0 4xa1 4xa1 4xa3 4xa4 4xa6

45 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name MYH7_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–842； UniProt 1–842

Myosin light chain 1/3, skeletal muscle isoform

OrganismNot specified

UniProt P05977

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Beta-cardiac myosin II × 1 （P12883） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
7qio 7qio

2 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7nep 8efd 8efe 9gz1 9yop 9yp4 9yp9 9yr7 9yrg 9yrh

10 assemblies

View Construct and Data Evidence
UniProt name MYL1_MOUSE
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–188； UniProt 1–188

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8efd
Deposition date deposition_date2022-09-08
Structure title titleHuman cardiac myosin II and associated essential light chain in the rigor conformation
Keywords keywordsactin, tropomyosin, myosin, cardiac, CONTRACTILE PROTEIN; CONTRACTILE PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8efd__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8efd__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8efd__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）37.14 Å
Rg (electron density)37.38 Å
Total Rg37.67 Å
Atom count7107
Residues886
Excluded volume126910 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8efd__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

Domain ID domain_id8efdA01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily60 —
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7. Citations (1)