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7u0f

HIV-1 Rev in complex with tubulin

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Tubulin alpha-1A chain

OrganismNot specified

UniProt P02550

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 150 Tubulin beta chain × 30 （P02554） Protein Rev × 90 （P04616） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 10 Tubulin beta chain × 2 （P02554） Protein Rev × 6 （P04616） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 10 Tubulin beta chain × 2 （P02554） Protein Rev × 6 （P04616） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2wbe

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1ffx 1ia0 1sa0 1sa1 1tub 1tvk 2hxf 2hxh 3edl 3edl 3edl 3j6e

46 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TBA1A_PIG
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–451； UniProt 1–451 Author chain C； PDBConstruct 1–451； UniProt 1–451

Tubulin beta chain

OrganismNot specified

UniProt P02554

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 150 Tubulin alpha-1A chain × 30 （P02550） Protein Rev × 90 （P04616） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 10 Tubulin alpha-1A chain × 2 （P02550） Protein Rev × 6 （P04616） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 10 Tubulin alpha-1A chain × 2 （P02550） Protein Rev × 6 （P04616） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2wbe

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1ffx 1ia0 1sa0 1sa1 1tub 1tvk 2hxf 2hxh 3edl 3edl 3edl 3j6e

159 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TBB_PIG
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–445； UniProt 1–445 Author chain D； PDBConstruct 1–445； UniProt 1–445

Protein Rev

Human immunodeficiency virus 1

UniProt P04616

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 150 Tubulin alpha-1A chain × 30 （P02550） Tubulin beta chain × 30 （P02554） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 10 Tubulin alpha-1A chain × 2 （P02550） Tubulin beta chain × 2 （P02554） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 10 Tubulin alpha-1A chain × 2 （P02550） Tubulin beta chain × 2 （P02554） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2x7l 2x7l 2x7l 2x7l 2x7l 2x7l 7u0f 7u0f 7u0f

9 assemblies

View Construct and Data Evidence
UniProt name REV_HV1B1
Isoform —
PDB entities 3
Chains and sequence ranges Author chain E； PDBConstruct 1–116； UniProt 1–116 Author chain F； PDBConstruct 1–116； UniProt 1–116 Author chain G； PDBConstruct 1–116； UniProt 1–116 Author chain H； PDBConstruct 1–116； UniProt 1–116 Author chain I； PDBConstruct 1–116； UniProt 1–116 Author chain J； PDBConstruct 1–116； UniProt 1–116

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7u0f
Deposition date deposition_date2022-02-18
Structure title titleHIV-1 Rev in complex with tubulin
Keywords keywordsRev, tubulin, HIV-1, VIRAL PROTEIN; VIRAL PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7u0f__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7u0f__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7u0f__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)205.90 Å
Total Rg206.00 Å
Atom count248535
Residues31305
Excluded volume4380900 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7u0f__assembly_1__model_1 150-meric （150） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7u0f__assembly_2__model_1 decameric （10） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 7u0f__assembly_3__model_1 decameric （10） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 6 domains

CATH v4.4 (6 domains)

Domain ID domain_id7u0fA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1440 — Tubulin/FtsZ, GTPase domain
Domain ID domain_id7u0fB01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1440 — Tubulin/FtsZ, GTPase domain
Domain ID domain_id7u0fB02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily600 — Helix hairpin bin
Domain ID domain_id7u0fC01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1440 — Tubulin/FtsZ, GTPase domain
Domain ID domain_id7u0fD01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1440 — Tubulin/FtsZ, GTPase domain
Domain ID domain_id7u0fD02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1330 — 60s Ribosomal Protein L30; Chain: A;
Homologous superfamily homologous superfamily20 — Tubulin/FtsZ, C-terminal domain
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7. Citations (1)